Recent Publications
This is an overview of the work from the Aleksunes lab. For a full list of our publications, please check us out on Pubmed.
Machine Learning Modeling for ABC Transporter Efflux and Inhibition
Daood NJ, Carey SR, Chung E, Wang T, Kreutz A, Girireddy M, Chakravarti S, Kleinstreuer NC, Tiley JB, Aleksunes LM, Zhu H. 2025, Mol Pharmaceutics
Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes
Rivera-Núñez Z, Kinkade C, Brinker A, Zhang R, Buckley B, Brunner J, Ohman-Strickland P, Qiu X, Qasem RJ, Fallon JK, Smith PC, Miller RK, Salafia CS, O’Connor TG, Aleksunes LM, Barrett ES, 2025, Environ Health Persp
Pathological Findings of Immunotherapy-Induced Nephrotoxicity in a Humanized Immune System Mouse Model
Asby SC, Thompson LE, Goedken M, Lucia SM, Dominguez AT, Kar A, Pitts TM, Kiseljak-Vassiliades K, Lang J, Aleksunes LM, Joy MS, 2025, Kidney International
Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter
Danielle Kozlosky, Cathleen Doherty, Brian Buckley, Michael Goedken, Richard Miller, Dan Dongeun Huh, Emily Barrett, Lauren Aleksunes, 2024, Toxicological Sciences
Placental BCRP Transporter Reduces Cadmium Accumulation and Toxicity in Immortalized Human Trophoblasts
Ranran Zhang, Lauren Walker, Xia Wen, Cathleen Doherty, Ludwik Gorczyca, Brian Buckley, Emily Barrett, Lauren Aleksunes, 2023, Reproductive Toxicology
Integrating Concentration-Dependent Toxicity Data and Toxicokinetics To Inform Hepatotoxicity Response Pathways
Daniel Russo, Lauren Aleksunes, Katy Goyak, Hua Qian, Hao Zhu, 2023, Environmental Science Technology
Prenatal Cadmium Exposure and Maternal Sex Steroid Hormone Concentrations Across Pregnancy
Zorimar Rivera-Núñez, Megan Hansel, Camila Capurro, Danielle Kozlosky, Christina Wang, Cathleen Doherty, Brian Buckley, Pam Ohman-Strickland, Rich Miller, Tom O’Connor, Lauren Aleksunes, Emily Barrett, 2023, Toxics
Cadmium Reduces Growth of Male Fetuses by Impairing Development of the Placental Vasculature and Reducing Expression of Nutrient Transporters
Danielle Kozlosky, Alexander Lu, Cathleen Doherty, Brian Buckley, Michael Goedken, Rich Miller, Emily Barrett, Lauren Aleksunes, 2023, Toxicology and Applied Pharmacology
Optimized Extraction and Analysis Methods Using Liquid Chromatography-Tandem Mass Spectrometry for Zearalenone and Metabolites in Human Placental Tissue
Abigail Lazofsky, Anita Brinker, Ruby Gupta, Emily Barrett, Lauren Aleksunes, Zorimar Rivera-Núñez, Brian Buckley, 2023, Heliyon
Gadolinium During Human Pregnancy Following Administration of Gadolinium Chelate Before Pregnancy
Rachel Coyte, Thomas Darrah, John Olesik, Emily Barrett, Thomas O’Connor, Jessica Brunner, Tanzy Love, Rogelio Perez-D’Gregorio, Henry Wang, Lauren Aleksunes, Brian Buckley, Cathleen Doherty, Richard Miller, 2023, Birth Defects Research
Data-Driven Quantitative Structure-Activity Relationship Modeling for Human Carcinogenicity by Chronic Oral Exposure
Elena Chung, Daniel Russo, Heather Ciallella , Yu-Tang Wang, Min Wu, Lauren Aleksunes, Hao Zhu, 2023, Environmental Science Technology
Protective Role of the Placental Efflux Transporter BCRP/ABCG2 in the Relationship Between Prenatal Cadmium Exposure, Placenta Weight, and Size at Birth
Emily Barrett, Zorimar Rivera-Núñez , Kylie Getz, Pamela Ohman-Strickland, Ranran Zhang, Danielle Kozlosky, Cathleen Doherty, Brian Buckley, Jessica Brunner, Richard Miller, Thomas O’Connor, Lauren Aleksunes, 2023, Environmental Research
High-Throughput Screening of Toxicants that Modulate Extravillous Trophoblast Migration
Cassandra Meakin, Christine Kim, Thomas Lampert, Lauren Aleksunes, 2023, Toxicology Letters
