{"id":363,"date":"2020-07-09T16:51:59","date_gmt":"2020-07-09T16:51:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/ann-stock-lab\/?page_id=363"},"modified":"2025-06-11T17:59:55","modified_gmt":"2025-06-11T17:59:55","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Complete List of Publications<\/a><\/h2>\n

Selected Reviews<\/h3>\n

Stock, A.M., Robinson, V.L. and Goudreau, P.N. (2000) Two-component signal transduction.<\/a> Annu. Rev. Biochem.<\/em> 69:183-215.<\/p>\n

Gao, R., Bouillet, S. and Stock, A.M. (2019) Structural basis of response regulator function.<\/a> Annu. Rev. Microbiol.<\/em> 73:175-197.<\/p>\n

Selected Publications<\/h3>\n

Agbekudzi, A., Arapov, T.D., Stock, A.M., and Scharf, B.E. (2024) The dual role of a novel Sinorhizobium meliloti<\/em> chemotaxis protein CheT in signal termination and adaptation.<\/a> Mol. Microbiol.<\/em> 122:429-446.<\/p>\n

Gao, R., Wu, T., and Stock, A.M. (2024) A conserved inhibitory interdomain interaction regulates DNA-binding activities of hybrid two-component systems in Bacteroides<\/em>.<\/a> mBio<\/em> 15:e0122024.<\/p>\n

Gao, R., Brokaw, S.E., Li, Z., Helfant, L.J., Wu, T., Malik, M., and Stock, A.M. (2022) Exploring the mono-\/bistability range of positively autoregulated signaling systems in the presence of competing transcription factor binding sites.<\/a> PLoS Comput. Biol. <\/em>18:e1010738.<\/p>\n

Zhou, Y., Pu, Q., Chen, J., Hao, G., Gao, R., Ali, A., Hsiao, A., Stock, A.M., Goulian, M., and Zhu, J. (2021) Thiol-based functional mimicry of phosphorylation of the two-component system response regulator ArcA promotes pathogenesis in enteric pathogens.<\/a> Cell Rep.<\/em> 37:110147.<\/p>\n

Gao, R., Helfant, L.J., Wu, T., Li, Z., Brokaw, S.E., and Stock, A.M. (2021) A balancing act in transcription regulation by response regulators: titration of transcription factor activity by decoy DNA binding sites.<\/a> Nucleic Acids Res.<\/em> 49:11537-11549.<\/p>\n

Bouillet, S., Wu, T., Chen, S., Stock, A.M., Gao, R. (2020) Structural asymmetry does not indicate hemi-phosphorylation in the bacterial histidine kinase CpxA.<\/a> J. Biol. Chem.<\/em> 295:8106-8117. Editor’s Pick<\/strong> with Highlight<\/a><\/p>\n

Bezar, I.F., Mashruwala, A.A., Boyd, J.M. and Stock, A.M. (2019) Drug-like fragments inhibit agr<\/em>-mediated virulence expression in Staphylococcus aureus<\/em>.<\/a> Sci. Rep.<\/em> 9:6786.<\/p>\n

Gao, R. and Stock, A.M. (2018) Overcoming the cost of positive autoregulation by accelerating the response with a coupled negative feedback.<\/a> Cell Rep.<\/em> 24:3061-3071.<\/p>\n

Gao, R. and Stock, A.M. (2018) Quantitative analysis of intracellular response regulator phosphatase activity of histidine kinases.<\/a> Methods Enzymol.<\/em> 607:301-319.<\/p>\n

Gao, R., Godfrey, K.A., Sufian, M.A. and Stock, A.M. (2017) Counterbalancing regulation in response memory of a positively autoregulated two-component system.<\/a> J. Bacteriol.<\/em> 199:e00390-17. Featured<\/strong> with Commentary<\/a><\/p>\n

Gao, R. and Stock, A.M. (2017) Quantitative kinetic analyses of shutting off a two-component system.<\/a>\u00a0 mBio<\/em> 8:e00412-17.<\/p>\n

Gao, R. and Stock, A.M. (2015) Temporal hierarchy of gene expression mediated by transcription factor binding affinity and activation dynamics.<\/a>\u00a0 mBio<\/em> 6:e00686-15.<\/p>\n

Gao, R. and Stock, A.M. (2013) Evolutionary tuning of protein expression levels of a positively autoregulated two-component system.<\/a> PLOS Genetics<\/em> 9:e1003927.<\/p>\n

Leonard, P.G., Golemi-Kotra, D. and Stock, A.M. (2013) Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus<\/em> VraR activation.<\/a> Proc. Natl. Acad. Sci. USA<\/em> 110:8525-8530.<\/p>\n

Barbieri, C.M., Wu, T. and Stock, A.M. (2013) Comprehensive analysis of OmpR phosphorylation, dimerization and DNA binding supports a canonical model for activation.<\/a> J. Mol. Biol.<\/em> 425:1612-1626.<\/p>\n

Gao, R. and Stock, A.M. (2013) Probing kinase and phosphatase activities of two-component systems in vivo<\/em> with concentration-dependent phosphorylation profiling.<\/a> Proc. Natl. Acad. Sci. USA<\/em> 110:672-677.<\/p>\n

Leonard, P.G., Bezar, I., Sidote, D.J. and Stock, A.M. (2012) Identification of a hydrophobic cleft in the LytTR domain of AgrA as a locus for small molecule interactions that inhibit DNA binding.<\/a> Biochemistry<\/em> 51:10035-10043.<\/p>\n

Tang, Y.T., Gao, R., Havranek, J.J., Groisman, E.A., Stock, A.M. and Marshall, G.R. (2012) Inhibition of bacterial virulence:drug-like molecules targeting the Salmonella enterica<\/em> PhoP response regulator.<\/a> Chem. Biol. Drug Des.<\/em> 79:1007-1017.<\/p>\n

Barbieri, C.M., Mack, T.R., Robinson, V.L., Miller, M.T. and Stock, A.M. (2010) Regulation of response regulator autophosphorylation through interdomain contacts.<\/a> J. Biol. Chem.<\/em> 285:32325-32335. Paper of the Week<\/strong> with Commentary<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Complete List of Publications Selected Reviews Stock, A.M., Robinson, V.L. and Goudreau, P.N. (2000) Two-component signal transduction. Annu. Rev. Biochem. 69:183-215. Gao, R., Bouillet, S. and Stock, A.M. (2019) Structural … Read More<\/a><\/p>\n","protected":false},"author":21,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublications - Ann Stock Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Ann Stock Laboratory\" \/>\n<meta property=\"og:description\" content=\"Complete List of Publications Selected Reviews Stock, A.M., Robinson, V.L. and Goudreau, P.N. (2000) Two-component signal transduction. Annu. Rev. Biochem. 69:183-215. Gao, R., Bouillet, S. and Stock, A.M. (2019) Structural … Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Ann Stock Laboratory\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-11T17:59:55+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/\",\"url\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/\",\"name\":\"Publications - Ann Stock Laboratory\",\"isPartOf\":{\"@id\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/#website\"},\"datePublished\":\"2020-07-09T16:51:59+00:00\",\"dateModified\":\"2025-06-11T17:59:55+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/#website\",\"url\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/\",\"name\":\"Ann Stock Laboratory\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/sites.rutgers.edu\/ann-stock-lab\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Publications - Ann Stock Laboratory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/","og_locale":"en_US","og_type":"article","og_title":"Publications - Ann Stock Laboratory","og_description":"Complete List of Publications Selected Reviews Stock, A.M., Robinson, V.L. and Goudreau, P.N. (2000) Two-component signal transduction. Annu. Rev. Biochem. 69:183-215. Gao, R., Bouillet, S. and Stock, A.M. (2019) Structural … Read More","og_url":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/","og_site_name":"Ann Stock Laboratory","article_modified_time":"2025-06-11T17:59:55+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/","url":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/","name":"Publications - Ann Stock Laboratory","isPartOf":{"@id":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/#website"},"datePublished":"2020-07-09T16:51:59+00:00","dateModified":"2025-06-11T17:59:55+00:00","breadcrumb":{"@id":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/"},{"@type":"ListItem","position":2,"name":"Publications"}]},{"@type":"WebSite","@id":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/#website","url":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/","name":"Ann Stock Laboratory","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/pages\/363"}],"collection":[{"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/comments?post=363"}],"version-history":[{"count":33,"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/pages\/363\/revisions"}],"predecessor-version":[{"id":734,"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/pages\/363\/revisions\/734"}],"wp:attachment":[{"href":"https:\/\/sites.rutgers.edu\/ann-stock-lab\/wp-json\/wp\/v2\/media?parent=363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}