{"id":160,"date":"2017-12-22T18:11:13","date_gmt":"2017-12-22T18:11:13","guid":{"rendered":"http:\/\/sites.rutgers.edu\/professor-example\/?page_id=160"},"modified":"2025-08-22T15:50:34","modified_gmt":"2025-08-22T15:50:34","slug":"courses","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/charles-roth\/courses\/","title":{"rendered":"Courses Taught"},"content":{"rendered":"

Fall 2025<\/h3>\n

16:125:590\/16:155:544: Drug Delivery Fundamentals and Applications<\/strong><\/p>\n

Wednesdays, 5:40 – 8:40 pm, BME-116<\/p>\n

Syllabus<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Week<\/em><\/td>\nClass date<\/em><\/td>\nTopic<\/em><\/td>\n<\/tr>\n
\u00a0<\/strong><\/td>\n\u00a0<\/strong><\/td>\nDrug Delivery Barriers and Formulations<\/strong><\/td>\n<\/tr>\n
1<\/td>\nSept. 3<\/td>\nIntroduction and Overview<\/td>\n<\/tr>\n
2<\/td>\nSept. 10<\/td>\nPharmacokinetics<\/td>\n<\/tr>\n
3<\/td>\nSept. 17<\/td>\nDrug Conjugates and Nanoparticles<\/td>\n<\/tr>\n
4<\/td>\nSept. 24<\/td>\nCellular and Intracellular Transport of Drugs<\/td>\n<\/tr>\n
5<\/td>\nOct. 1<\/td>\nTransport in Tissues<\/td>\n<\/tr>\n
6<\/td>\nOct. 8<\/td>\nPharmaceutical Dosage Forms<\/td>\n<\/tr>\n
 <\/td>\n\u00a0<\/strong><\/td>\nEngineered Drug Delivery Systems<\/strong><\/td>\n<\/tr>\n
7<\/td>\nOct. 15<\/td>\nControlled Release Drug Delivery Systems<\/td>\n<\/tr>\n
8<\/td>\nOct. 22<\/td>\nPhysiologically Targeted Drug Delivery<\/td>\n<\/tr>\n
9<\/td>\nOct. 29<\/td>\nMidterm Exam (covers Modules 1-7)<\/em><\/td>\n<\/tr>\n
10<\/td>\nNov. 5<\/td>\nPrecision Targeted Drug Delivery<\/td>\n<\/tr>\n
 <\/td>\n\u00a0<\/strong><\/td>\nApplications<\/strong><\/td>\n<\/tr>\n
11<\/td>\nNov. 12<\/td>\nTransdermal Drug Delivery<\/td>\n<\/tr>\n
12<\/td>\nNov. 19<\/td>\nGI and Pulmonary Delivery<\/td>\n<\/tr>\n
 <\/td>\nNov. 26<\/td>\nNo class \u2013 Happy Thanksgiving!<\/em><\/td>\n<\/tr>\n
13<\/td>\nDec. 3<\/td>\nGene and Oligonucleotide Delivery \u2013 part I<\/td>\n<\/tr>\n
14<\/td>\nDec. 10<\/td>\nGene and Oligonucleotide Delivery \u2013 part II<\/td>\n<\/tr>\n
15<\/td>\n <\/td>\nTerm Project Submission <\/em><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/h3>\n

Spring 2025<\/h3>\n

14:125:306: Biomedical Kinetics and Thermodynamics<\/strong><\/p>\n

Mondays and Wednesdays, 3:50 – 5:10 pm, BME-102<\/p>\n

Syllabus\u00a0<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Week<\/strong><\/td>\nDate<\/strong><\/td>\nTopic<\/strong><\/td>\nReading (Tinoco)<\/strong><\/td>\nTo Do<\/strong><\/td>\n<\/tr>\n
1<\/td>\nJan. 22<\/td>\nIntroduction; forms of energy<\/td>\nChapter 1<\/td>\n <\/td>\n<\/tr>\n
2<\/td>\nJan. 27<\/td>\nFirst law of thermodynamics<\/td>\nChapter 2<\/td>\n <\/td>\n<\/tr>\n
Jan. 29<\/td>\nCalculation of thermodynamic properties<\/td>\n\u2193<\/td>\n <\/td>\n<\/tr>\n
3<\/td>\nFeb. 3<\/td>\nEntropy and the second law of thermodynamics<\/td>\nChapter 3<\/td>\nPS1<\/td>\n<\/tr>\n
Feb. 5<\/td>\nThermodynamic relationships from multivariable calculus<\/td>\n\u2193<\/td>\nQuiz 1<\/td>\n<\/tr>\n
4<\/td>\nFeb. 10<\/td>\nCalculations with entropy and free energy<\/td>\n\u2193<\/td>\nPS2<\/td>\n<\/tr>\n
Feb. 12<\/td>\nFree energy and chemical potential<\/td>\nChapter 4<\/td>\nQuiz 2<\/td>\n<\/tr>\n
5<\/td>\nFeb. 17<\/td>\nThermodynamic activity<\/td>\n\u2193<\/td>\n <\/td>\n<\/tr>\n
Feb. 19<\/td>\nProtein biochemistry<\/td>\n <\/td>\n <\/td>\n<\/tr>\n
6<\/td>\nFeb. 24<\/td>\nProtein titration<\/td>\nChapter 4<\/td>\nPS3<\/td>\n<\/tr>\n
Feb. 26<\/td>\nNucleic acid structure and hybridization<\/td>\nChapter 5<\/td>\nQuiz 3<\/td>\n<\/tr>\n
7<\/td>\nMar. 3<\/td>\nDesign of primers for polymerase chain reaction<\/td>\nChapter 4<\/td>\nPS4<\/td>\n<\/tr>\n
Mar. 5<\/td>\nReview for Midterm Exam<\/td>\n <\/td>\nQuiz 4<\/td>\n<\/tr>\n
8<\/td>\nMar. 10<\/td>\nMidterm Exam<\/em><\/td>\n <\/td>\nExam 1<\/td>\n<\/tr>\n
Mar. 12<\/td>\nPhysical equilibria: solubility, dialysis<\/td>\nChapter 6<\/td>\n <\/td>\n<\/tr>\n
 <\/td>\nMar. 15-23<\/td>\nNo class \u2013 Enjoy Spring Break!!!<\/em><\/td>\n <\/td>\n <\/td>\n<\/tr>\n
9<\/td>\nMar. 24<\/td>\nLigand-receptor binding: Langmuir adsorption<\/td>\nChapter 5<\/td>\n <\/td>\n<\/tr>\n
Mar. 26<\/td>\nLigand-receptor binding: Scatchard and Hill analyses<\/td>\nChapter 6<\/td>\nPS5<\/td>\n<\/tr>\n
10<\/td>\nMar. 31<\/td>\nOsmotic pressure<\/td>\nChapter 6<\/td>\nPS6<\/td>\n<\/tr>\n
Apr. 2<\/td>\nElectrochemistry<\/td>\nChapter 7<\/td>\n <\/td>\n<\/tr>\n
11<\/td>\nApr. 7<\/td>\nActive transport<\/td>\n\u2193<\/td>\n <\/td>\n<\/tr>\n
Apr. 9<\/td>\nAbsorbance and Fluorescence<\/td>\nChapter 13<\/td>\n <\/td>\n<\/tr>\n
12<\/td>\nApr. 14<\/td>\nKinetic analysis I<\/td>\nChapter 9<\/td>\nPS7<\/td>\n<\/tr>\n
Apr. 16<\/td>\nKinetic analysis II<\/td>\n\u2193<\/td>\nQuiz 6<\/td>\n<\/tr>\n
13<\/td>\nApr. 21<\/td>\nEnzyme kinetics I<\/td>\nChapter 10<\/td>\nPS8<\/td>\n<\/tr>\n
Apr. 23<\/td>\nEnzyme kinetics II<\/td>\n\u2193<\/td>\nQuiz 7<\/td>\n<\/tr>\n
14<\/td>\nApr. 28<\/td>\nPharmacokinetics I<\/td>\nNotes<\/td>\nPS9<\/td>\n<\/tr>\n
Apr. 30<\/td>\nPharmacokinetics II<\/td>\n\u2193<\/td>\nQuiz 8<\/td>\n<\/tr>\n
15<\/td>\nMay.5<\/td>\nBiosensors<\/td>\n <\/td>\nPS10?<\/td>\n<\/tr>\n
16<\/td>\nMay 14<\/td>\nFinal Exam 12:00-3:00 pm<\/em><\/td>\n <\/td>\nExam 2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n


\nFall 2022<\/span><\/p>\n

16:155:531: Biochemical Engineering<\/strong><\/p>\n

Wednesdays, 5:40 – 8:40 pm, SEC-205<\/p>\n

Syllabus\u00a0<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Module<\/em><\/td>\nDate<\/em><\/td>\nTopic<\/em><\/td>\nChapter<\/em><\/td>\nGuest\/discussion<\/em><\/td>\n<\/tr>\n
1<\/td>\nSept. 7<\/td>\nIntroduction<\/td>\n1<\/td>\n<\/td>\n<\/tr>\n
2<\/td>\nSept. 14<\/td>\nProtein structure and stability<\/td>\n2.2.1<\/td>\nProf. Schuster<\/td>\n<\/tr>\n
3<\/td>\nSept. 21<\/td>\nEnzymes<\/td>\n3<\/td>\nProf. Chundawat<\/td>\n<\/tr>\n
4<\/td>\nSept. 28 Oct. 5<\/td>\nCell growth kinetics<\/td>\n6, 7<\/td>\n<\/td>\n<\/tr>\n
<\/td>\nOct. 19<\/td>\nQuiz 1 (Modules 1-4)<\/em><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
5<\/td>\nOct. 12<\/td>\nBioreactors<\/td>\n9<\/td>\n<\/td>\n<\/tr>\n
6<\/td>\nOct. 26<\/td>\nAeration and Scale-up<\/td>\n10<\/td>\nDr. Brieva (Resilience)<\/td>\n<\/tr>\n
<\/td>\n\u00a0<\/em><\/td>\nDesign Study (Modules 5-6)<\/em><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
7<\/td>\nNov. 2<\/td>\nGenetic engineering and cell line development<\/td>\n8,14<\/td>\n<\/td>\n<\/tr>\n
8<\/td>\nNov. 9<\/td>\nMetabolic engineering<\/td>\n5, 14<\/td>\nProf. Zhang<\/td>\n<\/tr>\n
9<\/td>\nNov. 16<\/td>\nBioseparations<\/td>\n11<\/td>\n<\/td>\n<\/tr>\n
<\/td>\nNov. 30<\/td>\nQuiz 2 (Modules 7-9)<\/em><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
10<\/td>\nDec. 7<\/td>\nMonoclonal antibodies<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
11<\/td>\nDec. 14<\/td>\nCell and gene therapies<\/td>\n15<\/td>\n<\/td>\n<\/tr>\n
<\/td>\n\u00a0<\/em><\/td>\nIntegrative Study (emphasizing Modules 10-11)<\/em><\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/h3>\n

Previous Courses Taught<\/h3>\n

2001 Instructor, \u201cEnzyme Engineering\u201d (155:534)
\nEnrollment: 5 students<\/p>\n

2001-2004, 2022-2025 (8x) Instructor, \u201cBiomedical Kinetics and Thermodynamics\u201d (125:314; 125:306)
\nCumulative enrollment: 471 students<\/p>\n

2001-2002 (2x) Instructor, \u201cChemical Engineering Analysis I\u201d (155:201)
\nCumulative enrollment: 80 students<\/p>\n

2002 Co-instructor, \u201cIntroduction to Biomedical Engineering\u201d (125:201), 8 lectures
\nEnrollment: 85 students<\/p>\n

2003-2008 (6x) Co-instructor, \u201cBME Measurements and Analysis Laboratory\u201d (125:314), 2 lectures + laboratories
\nCumulative enrollment: ~400 students<\/p>\n

2004-2007 (4x) Instructor, \u201cAdvanced Chemical Engineering Thermodynamics\u201d (155:511)
\nCumulative enrollment: 55 students<\/p>\n

2005-2010 (4x) Instructor, \u201cIntegrative Molecular and Cellular Bioengineering\u201d (125:584)
\nCumulative enrollment: 39 students<\/p>\n

2008 Lead Instructor, \u201cBME Measurements and Analysis Laboratory\u201d (125:315)
\nEnrollment: 72 students<\/p>\n

2008 Instructor, \u201cPreparing Future Faculty II\u201d (125:632)
\nEnrollment: 11 students<\/p>\n

2010 Instructor, \u201cPreparing Future Faculty I\u201d (125:631)
\nEnrollment: 9 students<\/p>\n

2009, 2011 (2x) Instructor, \u201cPharmaceutical Organic Nanotechnology (Drug Delivery)\u201d (155:544)
\nCumulative enrollment: 29 students<\/p>\n

2009, 2011 (2x) Instructor, \u201cNanotechnology in Cancer\u201d (01:090:101)
\nCumulative enrollment: 40 students<\/p>\n

2009-2011 (3x) Instructor, \u201cChemical Engineering Kinetics\u201d (155:411)
\nCumulative enrollment: 183 students<\/p>\n

2012-21 (8x) Instructor, \u201cDrug Delivery Principles and Applications\u201d (125:590\/155:544)
\nCumulative enrollment: 230 students<\/p>\n

2012-14 (3x) Instructor, \u201cIntroduction to Biochemical Engineering\u201d (155:411)
\nCumulative enrollment: 269 students<\/p>\n

2013-18 (6x) Instructor, \u201cTeaching in the Engineering Curriculum\u201d (155:605)
\nCumulative enrollment: 60 students<\/p>\n

2016-17 (2x) Instructor, \u201cBiological Foundations of Chemical Engineering\u201d (155:210)
\nCumulative enrollment: 234 students<\/p>\n

2018-20 (2x) Instructor, \u201cOpportunities and Challenges in Nanomedicine\u201d (090:101)
\nCumulative enrollment: 36 students<\/p>\n

2019-22 (3x) Instructor, \u201cBiochemical Engineering\u201d (155:531)
\nCumulative enrollment: 50 students<\/p>\n

2021 Instructor, \u201cClinical Practicum\u201d (125:628)
\nEnrollment: 36 students<\/p>\n

2021 Co-Instructor, \u201cIntegrative Molecular and Cellular Bioengineering\u201d (125:584)
\nEnrollment: 33 students<\/p>\n","protected":false},"excerpt":{"rendered":"

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