{"id":567,"date":"2021-01-27T16:45:26","date_gmt":"2021-01-27T16:45:26","guid":{"rendered":"http:\/\/sites.rutgers.edu\/cndr\/?page_id=567"},"modified":"2025-12-19T16:01:41","modified_gmt":"2025-12-19T16:01:41","slug":"research","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/cndr\/research\/","title":{"rendered":"Research"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-586 aligncenter\" src=\"http:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-300x200.jpg 300w, https:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-1024x684.jpg 1024w, https:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-768x513.jpg 768w, https:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-1536x1025.jpg 1536w, https:\/\/sites.rutgers.edu\/cndr\/wp-content\/uploads\/sites\/603\/2021\/06\/Dr_Hu_2-2400-2048x1367.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<div>Our research focuses on:<\/div>\n<ul>\n<li>Validating diagnostic tools for Alzheimer&#8217;s disease in diverse populations<\/li>\n<li>Discovering new tests and theories related to frontotemporal degeneration and Lewy body disease<\/li>\n<li>Understanding why some people respond to anti-amyloid therapy but others don&#8217;t<\/li>\n<li>Role of inflammation in the aging brain<\/li>\n<li>Benefits of life long learning and social engagement on brain health<\/li>\n<li>Vascular damage in the sclera (white of the eye) as a window into the brain<\/li>\n<li>Developing deep scientific understanding of long COVID through genes, proteins, and organoids (brain in a dish)<\/li>\n<\/ul>\n<p>We are currently recruiting for the following studies.\u00a0 Please contact the specific coordinator listed or our central research email at <a href=\"mailto:memory411@rutgers.edu\">memory411@rutgers.edu<\/a><\/p>\n<h2>CSF, MRI, and PET biomarker of inflammation in Alzheimer&#8217;s disease<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>The goal of the study is to better understand how inflammatory changes in the brain can be detected in the spinal fluid, MRI, and PET scan<\/li>\n<li>We are looking for people with mild cognitive impairment (MCI) or mild dementia due to Alzheimer&#8217;s disease<\/li>\n<li>Contact: <a href=\"mailto:Memory411@rutgers.edu\">Memory411@rutgers.edu<\/a> or <a href=\"mailto:vsotelo@rutgers.edu\">Victor Sotelo<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Beyond haploinsufficiency: Biomarkers in frontotemporal lobar degeneration (FTLD) due to progranulin (<em>GRN<\/em>) mutations<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>The goal of the study is to determine if some people with mutated <em>GRN<\/em> genes create abnormal proteins in their spinal fluid and blood<\/li>\n<li>We are looking for people from families with known GRN mutations or inherited forms of frontotemporal dementia\/primary progressive aphasia<\/li>\n<li>Contact: <a href=\"mailto:Memory411@rutgers.edu\">Memory411@rutgers.edu<\/a> or <a href=\"mailto:vsotelo@rutgers.edu\">Victor Sotelo<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Brain fog in long COVID<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>The goal of <a href=\"https:\/\/sites.rutgers.edu\/cndr\/brain-fog-in-long-covid\/\">this study<\/a> is to describe inflammatory changes in the spinal fluid and blood of people who develop thinking and memory issues (&#8220;brain fog&#8221;) after recovering from COVID-19<\/li>\n<li>We are looking for people who had mild to moderate COVID-19 (never intubated) who feel their memory and thinking is worse than before the infection<\/li>\n<li>Contact: <a href=\"mailto:Memory411@rutgers.edu\">Memory411@rutgers.edu<\/a> or <a href=\"mailto:keb257@rwjms.rutgers.edu\">Kristen Briney<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Rutgers-Stanford Chinese Older Adult Study (COAST)<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>The goal of <a href=\"https:\/\/sites.rutgers.edu\/cndr\/coast\/\">this study<\/a> is to compare performance on Mandarin- and English cognitive tests among bilingual older adults, correlate performance on Mandarin testing with brain structure\/function, and determine diagnostic thresholds for cognitive impairment among Mandarin speakers<\/li>\n<li>Contact: <a href=\"mailto:lime@rwjms.rutgers.edu\">Mei-ling Li<\/a> or <a href=\"gsu@ifh.rutgers.edu\">Guibin Su<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Memory and Aging in South Asian Americans<\/h2>\n<ul>\n<li style=\"list-style-type: none\">\n<ul>\n<li>There are two on-going studies focusing on the aging brain in older South Asians\n<ul>\n<li>South Asian Aging Brain (SAAB)<\/li>\n<li>Studying Attitudes towards MRI Research in Older South Asians (SAMOSA)<\/li>\n<\/ul>\n<\/li>\n<li>Contact: <a href=\"mailto:memory411@rutgers.edu\">memory411@rutgers.edu<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<div class=\"row\">\n<div class=\"col-12\">\n<div class=\"page-header\"><\/div>\n<\/div>\n<\/div>\n<ul>\n<li style=\"list-style-type: none\"><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Our research focuses on: Validating diagnostic tools for Alzheimer&#8217;s disease in diverse populations Discovering new tests and theories related to frontotemporal degeneration and Lewy body disease Understanding why some people &hellip; <a href=\"https:\/\/sites.rutgers.edu\/cndr\/research\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":1456,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-567","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research - Cognitive Neurology and Dementia Research<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/cndr\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research - Cognitive Neurology and Dementia Research\" \/>\n<meta property=\"og:description\" content=\"Our research focuses on: Validating diagnostic tools for 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