{"id":363,"date":"2020-07-09T16:51:59","date_gmt":"2020-07-09T16:51:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/dignon-lab\/?page_id=363"},"modified":"2025-09-08T21:16:45","modified_gmt":"2025-09-08T21:16:45","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/dignon-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<ol>\n<li>Favetta B, Wang H, Cubuk J, Singh A, Barai M, Ramirez C, Zheng H, Gormley AJ, Murthy NS, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Soranno A, \u201cPhosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two membrane-associated condensate states\u201d, Nature Communications, 16(1):7970 (2025).<\/li>\n<li>Alberti S, Arosio P, Best RB, Boeynaems S, Cai D, Collepardo-Guevara R, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Dimova R, Elbaum-Garfinkle S, Fawzi NL, Fuxreiter M, \u201cCurrent practices in the study of biomolecular condensates: a community comment\u201d, nature communications, 16(1):7730 (2025).<\/li>\n<li>Kelley FM, Ani A, Pinlac EG, Linders B, Favetta B, Barai M, Ma Y, Singh A, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Gu Y, Schuster BS, \u201cControlled and orthogonal partitioning of large particles into biomolecular condensates\u201d, Nature communications, 16(1):3521 (2025).<\/li>\n<li><span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Dill KA, \u201cComputational procedure for predicting excipient effects on protein\u2013protein affinities\u201d, Journal of Chemical Theory and Computation, 20(3), 1479-88 (2024).<\/li>\n<li>Nassar R, Brini E, Parui S, Liu C, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Dill KA, \u201dAccelerating protein molecular dynamics with machine learning\u201d, Journal of Chemical Theory and Computation, 18, 1929-1935 (2022).<\/li>\n<li>Nassar R*, <strong><span style=\"color: #cc0033\">Dignon GL*<\/span><\/strong>, Razban RM*, Dill KA, \u201cThe protein folding problem: The role of theory\u201d, Journal of Molecular Biology, 433, 167126 (2021).<\/li>\n<li>Perdikari TM, Jovic N, <strong><span style=\"color: #cc0033\">Dignon GL<\/span><\/strong>, Kim YC, Fawzi NL, Mittal J, \u201cA predictive coarsegrained model for position-specific effects of post-translational modifications\u201d, Biophysical Journal, 120, 1187-1197 (2021).<\/li>\n<li>Ryan VH, Perdikari TM, Naik MT, Saueressig CF, Lins J, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Mittal J, Hart AC, Fawzi NL, \u201cTyrosine phosphorylation regulates hnRNPA2 granule protein partitioning &amp; reduces neurodegeneration\u201d, EMBO Journal, 40, e105001 (2021).<\/li>\n<li><span style=\"font-size: 1rem\">Zheng W*, <span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Xu X, Regy RM, Best RB, Zheng W, Mittal J, \u201cMolecular <\/span>details of protein condensates probed by microsecond-long atomistic simulations\u201d, Journal of Physical Chemistry B, 124, 11671-11679 (2020).<\/li>\n<li><span style=\"font-size: 1rem\">Regy RM, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Zheng W, Kim YC, Mittal J, \u201cSequence dependent phase separation <\/span>of protein-polynucleotide mixtures elucidated using molecular simulations\u201d, Nucleic Acids Research, 48, 12593-12603 (2020).<\/li>\n<li>Schuster BS*, <span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Jahnke CN, Simpkins AG, Hammer DA, Good MC, Mittal J, \u201cIdentifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine its Phase Separation Behavior\u201d, Proceedings of the National Academy of Sciences, 117, 11421-11431 (2020).<\/li>\n<li><span style=\"font-size: 1rem\">Zheng W, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Brown M, Kim YC, Mittal J, \u201cHydropathy patterning complements <\/span>charge patterning to describe conformational preferences of disordered proteins\u201d, Journal of Physical Chemistry Letters, 11, 3408-3415 (2020).<\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Best, RB, Mittal J, \u201cBiomolecular Phase Separation: From Molecular Driving <\/span>Forces to Macroscopic Properties\u201d, Annual Review of Physical Chemistry, 71, 53-75, (2020).<\/li>\n<li><span style=\"font-size: 1rem\">Conicella AE*, <span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Schmidt HB, Zerze GH, D\u2019Ordine AM, Kim YC, Rohatgi <\/span><span style=\"font-size: 1rem\">R,Ayala YM, Mittal J, Fawzi NL, \u201cTDP-43 \u2000-helical structure tunes liquid-liquid phase <\/span><span style=\"font-size: 1rem\">separation and function\u201d, Proceeding of the National Academy of Sciences, 117, 5883-5894 (2020).<\/span><\/li>\n<li><span style=\"font-size: 1rem\">Murthy A, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Kan Y, Zerze GH, Parekh S, Mittal J, Fawzi NL, \u201cMolecular interactions underlying liquid phase separation of the FUS low-complexity domain\u201d, Nature Structural and Molecular Biology, 26, 637-648 (2019).<\/span><\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Zheng W*, Kim YC, Mittal J, \u201cTemperature controlled liquid-liquid <\/span><span style=\"font-size: 1rem\">phase separation of disordered proteins\u201d, ACS Central Science, 5, 821-830 (2019).<\/span><\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Zheng W, Mittal J, \u201cSimulation methods for liquid-liquid phase separation of disordered proteins\u201d, Current Opinion in Chemical Engineering, 23, 92-98 (2019).<\/span><\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Zheng W*, Best RB, Kim YC, Mittal J, \u201cRelation between single-molecule <\/span><span style=\"font-size: 1rem\">properties and phase behavior of intrinsically disordered proteins\u201d, Proceedings of the <\/span><span style=\"font-size: 1rem\">National Academy of Sciences, 115, 9929-9934 (2018).<\/span><\/li>\n<li>Ryan VH, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Zerze GH, Chabata CV, Silva R, Conicella AE, Amaya J, <span style=\"font-size: 1rem\">Burke KA, Mittal J, Fawzi NL, \u201cMechanistic View of hnRNPA2 Low-Complexity Domain <\/span><span style=\"font-size: 1rem\">Structure, Interactions, and Phase Separation Altered by Mutation and Arginine <\/span><span style=\"font-size: 1rem\">Methylation\u201d, Molecular Cell, 69, 465-479 (2018).<\/span><\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL*<\/strong><\/span>, Zheng W*, Kim YC, Best RB, Mittal J, \u201cSequence determinants of protein <\/span><span style=\"font-size: 1rem\">phase behavior from a coarse-grained model\u201d, PLOS Computational Biology, 14, <\/span><span style=\"font-size: 1rem\">e1005941 (2018).<\/span><\/li>\n<li><span style=\"font-size: 1rem\"><span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Zerze GH, Mittal J, \u201cInterplay Between Membrane Composition and <\/span><span style=\"font-size: 1rem\">Structural Stability of Membrane-Bound IAPP\u201d, The Journal of Physical Chemistry B, <\/span><span style=\"font-size: 1rem\">121, 8661-8668 (2017).<\/span><\/li>\n<li>Monahan Z, Ryan VH, Janke AM, Burke KA, Zerze GH, O\u2019Meally R, <span style=\"color: #cc0033\"><strong>Dignon GL<\/strong><\/span>, Conicella <span style=\"font-size: 1rem\">AE, Zheng W, Best RB, Cole RN, Mittal J, Shewmaker F, Fawzi NL, \u201cPhosphorylation <\/span><span style=\"font-size: 1rem\">of the FUS low-complexity domain disrupts phase separation, aggregation, <\/span><span style=\"font-size: 1rem\">and toxicity\u201d, The EMBO Journal, 36, 2951-2967, (2017).<\/span><\/li>\n<\/ol>\n<p><a class=\"btn btn-primary\" href=\"https:\/\/scholar.google.com\/citations?user=NaqTJeAAAAAJ&amp;hl=en\" target=\"_self\" rel=\"noopener\">Google Scholar<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Favetta B, Wang H, Cubuk J, Singh A, Barai M, Ramirez C, Zheng H, Gormley AJ, Murthy NS, Dignon GL, Soranno A, \u201cPhosphorylation toggles the SARS-CoV-2 nucleocapsid protein between two &hellip; <a href=\"https:\/\/sites.rutgers.edu\/dignon-lab\/publications\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":21,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Publications - Dignon Lab<\/title>\n<meta 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