{"id":593,"date":"2021-01-29T18:08:02","date_gmt":"2021-01-29T18:08:02","guid":{"rendered":"http:\/\/sites.rutgers.edu\/driscoll-lab\/?page_id=593"},"modified":"2023-05-04T21:32:08","modified_gmt":"2023-05-04T21:32:08","slug":"publication","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/driscoll-lab\/publication\/","title":{"rendered":"Publications"},"content":{"rendered":"

 <\/p>\n

The most cited:<\/strong><\/h5>\n

Herndon, L.A., Schmeissner, P., Dudaronek, J, Listner, K.M., Brown, P.A., Sakano, Y., Paupard, M., Hall, D. and Driscoll, M. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. 2002. Nature 419: 808-14.<\/a><\/p>\n

<\/h5>\n

 <\/p>\n

Selected recent publications:<\/strong><\/h5>\n

Arnold, M.L., Cooper, J.F., Androwski, R., Ardeshna, S., Melentijevic, I., Smart, A.J., Guasp, R.J., Nguyen, K.C., Bai, G., Hall, D.H., Grant, B.D., and Driscoll, M. (2023) Intermediate filaments associate with aggresome-like structures and influence rate of cellular expulsion of neuronal disease aggregates. BioRxiv 501714 [Preprint]. Available from: https:\/\/doi.org\/10.1101\/2022.08.03.501714\u00a0 under revision Nature Communications<\/em><\/a><\/p>\n

Yang,\u00a0Y., Arnold,\u00a0M.L., Choy,\u00a0E. H., Lange,\u00a0C. M., Poon,\u00a0K., Broussalian,\u00a0M., Sun,\u00a0L.-H., Moreno,\u00a0T.M., Singh,\u00a0A., Driscoll, M., Kumsta,\u00a0C., Hansen, M. (2023) Inhibition of early-acting autophagy genes in\u00a0C. elegans<\/em>\u00a0neurons improves protein homeostasis, promotes exopher production, and extends lifespan via the ATG-16.2 WD40 domain <\/a>BioRxiv\u00a02022.12.12.520171;\u00a0 doi:\u00a0https:\/\/doi.org\/10.1101\/2022.12.12.520171<\/a>. Nature Aging<\/em><\/strong>, under review.<\/p>\n

Wang, Y.,\u00a0Arnold, ML.,\u00a0Smart, A.J.,\u00a0Wang, G.,\u00a0Morera, A.,\u00a0Nguyen, K.C.,\u00a0\u00a0Schweinsberg, P.J.,\u00a0Bai, G.,\u00a0Cooper, J.,\u00a0Hall, D.H.,\u00a0Driscoll, M.,\u00a0Grant, B.D.\u00a02023. Large vesicle extrusions from\u00a0<\/span>C. elegans<\/span>\u00a0neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell<\/span>. <\/span>Elife <\/span>Mar 2;12:e82227. doi: 10.7554\/eLife.82227. PMID <\/span>36861960<\/span><\/a><\/p>\n

Onken, B., Sedore, C.A., Coleman-Hulbert, A.L.,\u00a0 Hall, D. Johnson, E., Jones, E.G., Banse, S.A., Huynh, P., Guo, S.,\u00a0 Xue, J., Chen, E., Harinath, G., Foulger, A.C., Chao, E.A., Hope, J., Dipa Bhaumik, D., Plummer, W.T., Inman, D., Morshead, M., Guo, M., Lithgow, G.J., Phillips, P.C., and Driscoll, M. 2021. Metformin treatment of\u00a0diverse Caenorhabditis\u00a0<\/span>species reveals the importance of genetic background in longevity and healthspan extension outcomes. <\/span>Aging Cell <\/span><\/a>e13488. doi: 10.1111\/acel.13488. PMID:\u00a034837316\u00a0 <\/span>Science<\/span> Editors Choice highlighted <\/span>in \u201cIn Others Journals\u201d section<\/span> https:\/\/www.science.org\/doi\/10.1126\/science.acz9984<\/span><\/p>\n

Cooper, J., Guasp, R., Arnold,\u00a0 M., Grant, B, and Driscoll, M. 2021. Stress-induced increases in neuronal\u00a0exopher extrusion requires lipid biosynthesis, FGF and EGF RAS\/ERK signaling, PNAS<\/span>, <\/span>18:e2101410118\u00a0 PMID:\u00a0<\/span>34475208<\/span><\/a><\/p>\n

Laranjeiro, R.; Harinath, G, Pollard, A.K., Gaffney, C.J., Deane, C.S., Vanapalli, S.A., Etheridge, T. Szewczyk, N.J., and Driscoll, M. 2021. Spaceflight affects neuronal morphology and alters transcellular degradation of neuronal debris in adult <\/span>Caenorhabditis elegans<\/span>. <\/span>iScience<\/span>. 24(2):102105. PMID:\u00a033659873<\/span><\/a><\/p>\n

Rahman, M., Edwards, H., Birze, N., Gabrilska, R., Rumbaugh, K. P., Blawzdziewicz, J., Szewczyk, N. J., Driscoll, M., and Vanapalli, S.A. 2020.\u00a0NemaLife Chip: A micropillar-based microfluidic culture device optimized for aging studies on crawling\u00a0C. elegans.\u00a0Sci. Rep\u00a0\u00a0Oct 1;10(1):16190. doi: 10.1038\/s41598-020-73002-6\u00a0 PMID:\u00a033004810<\/a><\/p>\n

Onken, B., Kalinava, N., and Driscoll, M. 2020.\u00a0Gluoconeogenesis and PEPCK are criticalcomponents of healthy aging and Dietary restriction life extension.\u00a0PLoS Genetics,\u00a016(8):e1008982. doi: 10.1371\/journal.pgen.1008982.\u00a0PMID:\u00a032841230<\/a><\/p>\n

*Arnold, M.L., *Cooper, J., Grant, B.D., Driscoll,\u00a0Quantitative approaches for scoring\u00a0in vivo\u00a0neuronal aggregate and organelle extrusion in large exopher vesicles in\u00a0C. elegans.\u00a02020.\u00a0J Vis Exp.\u00a0Sep 18;(163). doi: 10.3791\/61368.\u00a0 PMID:\u00a033016946<\/a><\/p>\n

Abbott M, Banse SA, Melentijevic I, Jarrett CM, Ange JS, Sedore CA, Falkowski R, Blue BW, Coleman-Hulbert AL, Johnson E, Guo M, Lithgow GJ, Phillips PC, Driscoll M. A simplified design for the C. elegans<\/em> lifespan machine. <\/span>J Biol Methods. 2020 Oct 26;7(4):e137. doi: 10.14440\/jbm.2020.332. eCollection 2020. PMID: 33204740<\/span><\/span><\/a><\/p>\n

Wang, G., Sun, L., Reina, C.P., Song, I., Gabel, C.V., Driscoll, M. 2019.\u00a0Residues in the CED-4 CARD domain can modulate non-apoptotic neuronal regeneration functions independently from apoptosis,\u00a0Sci. Reports\u00a0Sep 16;9(1):13315. doi: 10.1038\/s41598-019-49633-9. PMID:31527664<\/a><\/p>\n

Laranjeiro, R., Harinath, G., Hewitt, J.E., Hartman, J.H., Royal, M.A., Meyer, J.N., Vanapalli, S.A., Driscoll, M. 2019.\u00a0Swim exercise in\u00a0C. elegans\u00a0extends neuromuscular and intestinal healthspan, enhances learning ability and protects against neurodegeneration.\u00a0Proc Natl Acad Sci USA. 2019 Nov 19;116(47):23829-23839. PMID:31685639.\u00a0F1000 recommended.<\/a><\/p>\n

Arnold, M.L., Smart, A.J., Melentijevic, I., Driscoll, M. 2018.\u00a0\u00a0Trash talk: disposal and remote degradation of neuronal garbage.\u00a0\u00a0BMC Biology\u00a0doi: 10.1186\/s12915-018-0487-6. PMID: 29382333<\/a><\/p>\n

Plummer, T.W., Harke, J., Lucanic, M. Chen, E., Bhaumik, D., Harinath, G., Coleman-Hulbert, A.L., Dumas, K.J., Onken, B., Johnson, E., Foulger, A.C., Guo, S., Crist, A.B., Presley, M.P., Xue, J., Sedore, C.A., Chamoli, M., Chang, C., Chen, M.K., Angeli, S., Royal, M., Willis, J.H., Edgar, D., Patel, S., Chao, E.A., Kamat, S., Hope, J., Ibanez-Ventoso, C., Kish, J.L., Guo, M.,\u00a0 Phillips, P., Lithgow, G.J., Driscoll, M.\u00a0\u00a02017. Standardized Protocols from the\u00a0Caenorhabditis\u00a0Intervention Testing Program 2013-2016: Conditions and Assays used for Quantifying the Development, Fertility and Lifespan of Hermaphroditic\u00a0Caenorhabditis\u00a0Strains\u00a0Nature Protocols Exchangedoi:10.1038\/protex.2016.086<\/a><\/p>\n

Lucanic, M., Plummer, WT, Chen, E., Harke, J., Foulger JC, Onken, B, \u00a0Coleman-Hulbert, AL, Dumas, KJ, Guo, S., Johnson, E.,\u00a0Bhaumik, D., Xue, J., Crist, AB, Presley, MP, Harinath, G.,\u00a0Sedore, CA, Chamoli, M., Kamat, S., Chen, MK,\u00a0Angeli, S., Chang, C., Willis, JH, Edgar, D, Royal, MA, Chao, EA, Patel, S., Garrett, T., Ibanez-Ventoso, C., Hope, J., Kish, JL, Guo, M,\u00a0Lithgow, GJ, Driscoll, M., Phillips, P.C., Lithgow, G. 2017.\u00a0\u00a0Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects\u00a0Nature Communications,\u00a08:14256\u00a0doi 10.1038\/ncomms1426.\u00a0PMID: 28220799<\/a><\/p>\n

Laranjeiro, R., Harinath, G., Braekman, B.P., Driscoll, M. 2017.\u00a0Single\u00a0<\/span>C. elegans<\/span>\u00a0swim sessions induce key features of mammalian exercise.<\/span>\u00a0\u00a0<\/span>BMC Biol.<\/span>\u00a015:30. doi: 10.1186\/s12915-017-0368-4. PMID: 28395669<\/span><\/a><\/p>\n

Melentijevic, I., Toth, M.L., Arnold, M.L., Guasp, R., Harinath, G. Nguyen, K.C., Taub, D., Parker, A., Neri, C., Gabel, C.V., Hall, D.H., and Driscoll, M. 2017.\u00a0C. elegans\u00a0neurons jettison protein aggregates and mitochondria under neurotoxic stress.\u00a0\u00a0Nature\u00a0542:367-371. PMID: 2817824.\u00a0\u00a0 Selected by F1000 as of exceptional significance in its field.\u00a0 (6 F1000 citations).\u00a0<\/a><\/p>\n

Ib\u00e1\u00f1ez-Ventoso, C., Herrera, C., Chen, E., Motto, D.,\u00a0and Driscoll\u00a0M.\u00a0Automated analysis of C. elegans swim behavior using CeleST software.\u00a02016. J Vis Exp.\u00a02016 Dec 7;(118). doi: 10.3791\/54359. PMID: 28060275<\/a><\/p>\n

Restif, C., Ibanez-Ventoso, C., Vora, M., Guo, S., Metaxas, D. and Driscoll, M. 2014. CeleST:\u00a0Computer vision software for quantitative analysis of\u00a0C. elegans\u00a0swim behavior reveals novel features of locomotion.\u00a0PLoS Computational Biology, 0(7):e1003702PMID: 25033081<\/a><\/p>\n

Vora, M., Shah, M., Ostafi, S., Onken, B., Xue, J., Ni, JZ, Gu, S., and Driscoll, M. 2013.\u00a0Deletion of microRNA-80 activates dietary restriction to extend\u00a0C. elegans\u00a0healthspan and lifespan.\u00a0PLoS Genetics\u00a0e1003737 PMID: 24009527<\/a><\/p>\n

Reina, C.P., Driscoll, M., and Gabel, C.V. 2013.\u00a0Neuronal repair: Apoptotic proteins make good.\u00a0Worm\u00a02(2):1-6. PMID: 24058867<\/a><\/p>\n

Toth, M. Melentijevic, I. Shah, L., Bhatia, A., Lu, K., Talwar, A., Naji, H., Ibanez-Ventoso, C., Ghose, P., Jevince, A., Herndon L., Bhanot, G., Rongo, C., Hall, D.H., and Driscoll, M. 2012.\u00a0Neurite sprouting and synapse deterioration in the aging\u00a0C. elegans\u00a0nervous system.\u00a0\u00a0J. Neurosci.\u00a032: 8778-90. PMID 22745480<\/a><\/p>\n

Pinan-Lucarre, B., Gabel, C., Reina, C., Hulme, S.E., Shevkoplyas, S.S., Slone, R.D., Xue, J., Weisberg, S., Whitesides, G., Samuel, A. and Driscoll, M. 2012.\u00a0The core apoptotic executioner proteins CED-3 and CED-4 promote neuronal regeneration in\u00a0C. elegans.\u00a0PLoS Biology,\u00a010(5):e1001331. PMID 22629231<\/a><\/p>\n

Yu, S. and Driscoll, M. 2011.\u00a0\u00a0EGF signaling comes of age: promotion of healthy aging in\u00a0C. elegans.\u00a0Exptl. Gerontol.46:129-134.<\/a><\/p>\n

Iwasa, H., Yu, S., Xue, J. and Driscoll, M. 2010.\u00a0Novel EGF pathway regulators modulate\u00a0C. elegans\u00a0healthspan and lifespan via EGF receptor, PLC-\u03b3 and IP3R activation.\u00a0Aging Cell\u00a04:490-505.<\/a><\/p>\n

Onken, B and Driscoll, M. 2010.\u00a0Metformin induces both a dietary restriction-like state and the oxidative stress response to extend\u00a0C. elegans\u00a0healthspan via an AMPK, LKB1, and SKN-1-dependent mechanism.\u00a0PLoS One\u00a05:e8758, pp. 1-12.<\/a><\/p>\n

 <\/p>\n

Monica’s webpage<\/a> for the full list of publications<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

  The most cited: Herndon, L.A., Schmeissner, P., Dudaronek, J, Listner, K.M., Brown, P.A., Sakano, Y., Paupard, M., Hall, D. and Driscoll, M. Stochastic and genetic factors influence tissue-specific decline … Read More<\/a><\/p>\n","protected":false},"author":1282,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-593","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublications - Driscoll C. elegans Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/driscoll-lab\/publication\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Driscoll C. elegans Lab\" \/>\n<meta property=\"og:description\" content=\"  The most cited: Herndon, L.A., Schmeissner, P., Dudaronek, J, Listner, K.M., Brown, P.A., Sakano, Y., Paupard, M., Hall, D. and Driscoll, M. 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