{"id":363,"date":"2020-07-09T16:51:59","date_gmt":"2020-07-09T16:51:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/glytsou-lab\/?page_id=363"},"modified":"2025-11-03T21:39:38","modified_gmt":"2025-11-03T21:39:38","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/glytsou-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Doshi, S. and Glytsou, C. (2025) <\/span>Mitochondrial Dynamics in Blood Cancer Development and Progression.<\/strong><\/a> Current Pharmacology Reports <\/span><\/em>https:\/\/doi.org\/10.1007\/s40495-025-00431-0<\/span><\/span><\/p>\n

La Vecchia, S., Doshi, S., Antonoglou, P., Kundu, T., Al Santli, W., Avrampou, K., Witkowski, M., Pellattiero, A., Magrin, F., Ames, K., Verma, A., Gritsman, K., Su, X., Mattarei, A., Aifantis, I., Scorrano, L., Glytsou, C. (2025) Small molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia.<\/strong><\/span><\/a> Science Advances <\/em>\u00a0https:\/\/www.science.org\/doi\/10.1126\/sciadv.adx8662<\/p>\n

Glaviano, A., Weisberg, E., Lam, H.Y.\u00a0et al.<\/i> (2025) Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia.<\/strong><\/span><\/a>\u00a0Nat Rev Clin Oncol<\/i>\u00a0https:\/\/doi.org\/10.1038\/s41571-025-01068-0<\/p>\n

Glytsou C. (2025) Electron Microscopy to Visualize and Quantify Mitochondrial Structure and Organellar Interactions in Cultured Cells During Senescence.<\/a><\/strong><\/span> Methods Mol Biol. 2025;2906:229-242. doi: 10.1007\/978-1-0716-4426-3_13. PMID: 40082359.<\/p>\n

Rigoni, G.*, Calvo, E.*, Glytsou, C.*, Carro-Alvarellos, M., Noguchi, M., Semenzato, M., Quirin, C., Caicci, F., Meneghetti, N., Sturlese, M., Ishihara, T., Moro, S., Rampazzo, C., Ishihara, N., Bezzo, F., Salviati, L., Vazquez, J., Sales, G., Romualdi, C., Enriquez, J. A., Scorrano, L., & Soriano, M. E. (2025). MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling.<\/a><\/strong> <\/span>Cell Metabolism doi.org\/10.1016\/j.cmet.2025.01.017<\/p>\n

Glytsou,\u00a0C.#,<\/sup> *<\/strong>, Chen, X.*<\/strong>, Zacharioudakis, E.*<\/strong>, Al-Santli, W., Zhou, H., Sun, Z., Zal, T., Zal, M.A., Ishizawa, J., Tibes, R., Tsirigos, A., Andreeff. M., Gavathiotis, E.#<\/sup>, Aifantis, I#<\/sup>. (2023). Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia.<\/strong><\/a><\/span> Cancer Discovery doi:10.1158\/2159-8290.CD-22-0601.<\/p>\n

Chen, X.*, Glytsou, C.*, Zhou, H., Narang, S., Reyna, D.E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y.S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R., and Aifantis, I. (2019). Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.<\/strong><\/a><\/span> Cancer Discov 9<\/em>, 890-909. doi: 10.1158\/2159-8290.CD-19-0117. PMC ID: PPMC6606342<\/p>\n

Commentary – Savona MR, Rathmell JC. (2019). Mitochondrial Homeostasis in AML and Gasping for Response in Resistance to BCL2 Blockade.<\/strong><\/a><\/span> Cancer Discov 9, <\/em>831-33. doi:10.1158\/2159-8290.CD-19-0510.<\/p>\n

Thandapani, P., Kloetgen, A.*, Witkowski, M.T.*, Glytsou, C.*, Lee, A.K., Wang, E., Wang, J., LeBoeuf, S.E., Avrampou, K., Papagiannakopoulos, T., Tsirigos, A., and Aifantis, I. (2021). Valine tRNA levels and availability regulate complex I assembly in leukaemia.<\/strong><\/a><\/span> Nature. doi: 10.1038\/s41586-021-04244-1<\/p>\n

DiNardo, C.D., Tiong, I.S., Quaglieri, A., MacRaild, S., Loghavi, S., Brown, F.C., Thijssen, R., Pomilio, G., Ivey, A., Salmon, J.M., Glytsou, C., Fleming, S.A., Zhang, Q., Ma, H., Patel, K.P., Kornblau, S.M., Xu, Z., Chua, C.C., Chen, X., Blombery, P., Flensburg, C., Cummings, N., Aifantis, I., Kantarjian, H., Huang, D.C.S., Roberts, A.W., Majewski, I.J., Konopleva, M., and Wei, A.H. (2020). Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.<\/strong><\/a> <\/span>Blood 135<\/em>, 791-803. doi: 10.1182\/blood.2019003988. PMC ID: PPMC7068032<\/p>\n

Giacomello, M., Pyakurel, A., Glytsou, C., and Scorrano, L. (2020). The cell biology of mitochondrial membrane dynamics.<\/strong><\/a><\/span> Nat Rev Mol Cell Biol 21<\/em>, 204-224. doi: 10.1038\/s41580-020-0210-7<\/p>\n

Glytsou, C., Calvo, E., Cogliati, S., Mehrotra, A., Anastasia, I., Rigoni, G., Raimondi, A., Shintani, N., Loureiro, M., Vazquez, J., Pellegrini, L., Enriquez, J.A., Scorrano, L., and Soriano, M.E. (2016). Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control.<\/strong><\/a><\/span> Cell Rep 17<\/em>, 3024-3034. doi: 10.1016\/j.celrep.2016.11.049. PMC ID: PPMC5186903<\/p>\n

Quintana-Cabrera, R., Quirin, C., Glytsou, C., Corrado, M., Urbani, A., Pellattiero, A., Calvo, E., Vazquez, J., Enriquez, J.A., Gerle, C., Soriano, M.E., Bernardi, P., and Scorrano, L. (2018). The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function.<\/strong><\/a> <\/span>Nat Commun 9<\/em>, 3399. doi: 10.1038\/s41467-018-05655-x. PMC ID: PPMC6109181<\/p>\n

Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L., Georgakilas, A.G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sorensen, C.S., Bartek, J., and Gorgoulis, V.G. (2018). Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.<\/strong><\/a> <\/span>Genome Biol 19<\/em>, 37. doi: 10.1186\/s13059-018-1401-9. PMC ID: PPMC5857109<\/p>\n

Aivaliotis, I.L., Pateras, I.S., Papaioannou, M., Glytsou, C., Kontzoglou, K., Johnson, E.O., and Zoumpourlis, V. (2012). How do cytokines trigger genomic instability?<\/strong><\/a><\/span> J Biomed Biotechnol 2012<\/em>, 536761. doi: 10.1155\/2012\/536761. PMC ID: PPMC3382994<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Doshi, S. and Glytsou, C. (2025) Mitochondrial Dynamics in Blood Cancer Development and Progression. Current Pharmacology Reports https:\/\/doi.org\/10.1007\/s40495-025-00431-0 La Vecchia, S., Doshi, S., Antonoglou, P., Kundu, T., Al Santli, W., … Read More<\/a><\/p>\n","protected":false},"author":21,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublications - Glytsou Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/glytsou-lab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Glytsou Lab\" \/>\n<meta property=\"og:description\" content=\"Doshi, S. and Glytsou, C. 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