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Publications

Our lab’s research focuses on three key topics – Health Services, Etiology, and the Environment. Key articles within each category are listed below.

Please visit my Google Scholar page for a complete list of publications that I have led and coauthored.

Health Services  

United States

  • Iyer HS, Kensler KH, Roscoe C, Opara C, He M, Kovac E, Garraway IP, Dien-Trinh Q, Rebbeck TR. Multidimensional Healthcare Access Barriers to Prostate-Specific Antigen Testing: A Nation-Wide Panel Study in the United States From 2006 to 2020. Cancer Med. 2024 Nov;13(21):e70358. doi: 10.1002/cam4.70358. PMID: 39503193; PMCID: PMC11538963.
  • Iyer HS, Stone BV, Roscoe C, Hsieh MC, Stroup AM, Wiggins CL, Schumacher FR, Gomez SL, Rebbeck TR, Trinh QD. Access to Prostate-Specific Antigen Testing and Mortality Among Men With Prostate Cancer. JAMA Netw Open. 2024 Jun 3;7(6):e2414582. doi: 10.1001/jamanetworkopen.2024.14582. PMID: 38833252; PMCID: PMC11151156.
  • Wadhwa A, Roscoe C, Duran EA, Kwan L, Haroldsen CL, Shelton JB, Cullen J, Knudsen BS, Rettig MB, Pyarajan S, Nickols NG, Maxwell KN, Yamoah K, Rose BS, Rebbeck TR, Iyer HS*, Garraway IP*. Neighborhood Deprivation, Race and Ethnicity, and Prostate Cancer Outcomes Across California Health Care Systems. JAMA Netw Open. 2024 Mar 4;7(3):e242852. doi: 10.1001/jamanetworkopen.2024.2852. PMID: 38502125; PMCID: PMC10951732. *Indicates equal contributions.
  • Kensler KH, Johnson R, Morley F, Albrair M, Dickerman BA, Gulati R, Holt SK, Iyer HS, Kibel AS, Lee JR, Preston MA, Vassy JL, Wolff EM, Nyame YA, Etzioni R, Rebbeck TR. Prostate Cancer Screening in African American Men: A Review of the Evidence. J Natl Cancer Inst. 2023 Sep 15:djad193. doi: 10.1093/jnci/djad193. Epub ahead of print. PMID: 37713266.
  • Stone BV, Labban M, Beatrici E, Filipas DK, D’Amico AV, Lipsitz SR, Choueiri TK, Kibel AS, Cole AP, Iyer HS, Trinh QD. The Association of County-level Prostate-specific Antigen Screening with Metastatic Prostate Cancer and Prostate Cancer Mortality. Eur Urol Oncol. 2023 Dec 27:S2588-9311(23)00286-9. doi: 10.1016/j.euo.2023.11.020. Epub ahead of print. PMID: 38155059.
  • Labban M, Chen CR, Frego N, Nguyen DD, Lipsitz SR, Reich AJ, Rebbeck TR, Choueiri TK, Kibel AS, Iyer HS, Trinh QD. Disparities in Travel-Related Barriers to Accessing Health Care From the 2017 National Household Travel Survey. JAMA Netw Open. 2023 Jul 3;6(7):e2325291. doi: 10.1001/jamanetworkopen.2023.25291. PMID: 37498602; PMCID: PMC10375305.
  • Iyer HS, Gomez SL, Chen JT, Trinh QD, Rebbeck TR. Trends in mortality among Black and White men with prostate cancer in Massachusetts and Pennsylvania: Race and neighborhood socioeconomic position. Cancer. 2021 Jul 15;127(14):2525-2534. doi: 10.1002/cncr.33506. Epub 2021 Apr 2. PMID: 33798264; PMCID: PMC8249310.

Sub-Saharan Africa

  • Fleming KA, Horton S, Wilson ML, Atun R, DeStigter K, Flanigan J, Sayed S, Adam P, Aguilar B, Andronikou S, Boehme C, Cherniak W, Cheung AN, Dahn B, Donoso-Bach L, Douglas T, Garcia P, Hussain S, Iyer HS, Kohli M, Labrique AB, Looi LM, Meara JG, Nkengasong J, Pai M, Pool KL, Ramaiya K, Schroeder L, Shah D, Sullivan R, Tan BS, Walia K. The Lancet Commission on diagnostics: transforming access to diagnostics. Lancet. 2021 Oct 5:S0140-6736(21)00673-5. doi: 10.1016/S0140-6736(21)00673-5. Epub ahead of print. PMID: 34626542; PMCID: PMC8494468.
  • Iyer HS, Flanigan J, Wolf NG, Schroeder LF, Horton S, Castro MC, Rebbeck TR. Geospatial evaluation of trade-offs between equity in physical access to healthcare and health systems efficiency. BMJ Glob Health. 2020 Oct;5(10):e003493. doi: 10.1136/bmjgh-2020-003493. PMID: 33087394; PMCID: PMC7580044.
  • Iyer HS, Chukwuma A, Mugunga JC, Manzi A, Ndayizigiye M, Anand S. A Comparison of Health Achievements in Rwanda and Burundi. Health Human Rights. 2018 Jun;20(1):199-211. PMID: 30008563; PMCID: PMC6039746.
  • Iyer HS, Hirschhorn LR, Nisingizwe MP, Kamanzi E, Drobac PC, Rwabukwisi FC, et al. (2017) Impact of a district-wide health center strengthening intervention on healthcare utilization in rural Rwanda: Use of interrupted time series analysis. PLoS ONE 12(8): e0182418

Etiology

Genetic ancestry (similarity), neighborhood context, and racial disparities

  • Iyer HS, Zeinomar N, Omilian AR, Perlstein M, Davis MB, Omene CO, Pawlish K, Demissie K, Hong CC, Yao S, Ambrosone CB, Bandera EV, Qin B. Neighborhood Disadvantage, African Genetic Ancestry, Cancer Subtype, and Mortality Among Breast Cancer Survivors. JAMA Netw Open. 2023 Aug 1;6(8):e2331295. doi: 10.1001/jamanetworkopen.2023.31295. PMID: 37647068; PMCID: PMC10469269.
  • Iyer HS, Gomez SL, Cheng I, Rebbeck TR(2022) Relative impact of genetic ancestry and neighborhood socioeconomic status on all-cause mortality in self-identified African Americans. PLoS ONE 17(8): e0273735

Neighborhood context, environmental exposures, and cardiometabolic risk

  • Fiffer MR, Li H, Iyer HS, Nethery RC, Sun Q, James P, Yanosky JD, Kaufman JD, Hart JE, Laden F. Associations between air pollution, residential greenness, and glycated hemoglobin (HbA1c) in three prospective cohorts of U.S. adults. Environ Res. 2023 Oct 13:117371. doi: 10.1016/j.envres.2023.117371. Epub ahead of print. PMID: 37839528.
  • Iyer HS, Kensler KH, Vaselkiv JB, Stopsack KH, Roscoe C, Bandera EV, Qin B, Jang TL, Lotan TL, James P, Hart JE, Mucci LA, Laden F, Rebbeck TR. Associations between Etiologic or Prognostic Tumor Tissue Markers and Neighborhood Contextual Factors in Male Health Professionals Diagnosed with Prostate Cancer. Cancer Epidemiol Biomarkers Prev. 2023 Aug 1;32(8):1120-1123. doi: 10.1158/1055-9965.EPI-23-0217. PMID: 37249585; PMCID: PMC10527012.
  • Iyer HS, Vaselkiv JB, Stopsack KH, Roscoe C, DeVille NV, Zhang Y, Penney KL, Balk SP, Fiorentino M, Hart JE, James P, De Vivo I, Mucci LA, Laden F, Rebbeck TR. Influence of Neighborhood Social and Natural Environment on Prostate Tumor Histology in a Cohort of Male Health Professionals. Am J Epidemiol. 2023 Sep 1;192(9):1485-1498. doi: 10.1093/aje/kwad112. PMID: 37139568.
  • Iyer HS, Hart JE, Fiffer MR, Elliott EG, Yanosky JD, Kaufman JD, Puett RC, Laden F. Impacts of long-term ambient particulate matter and gaseous pollutants on circulating biomarkers of inflammation in male and female health professionals. Environ Res. 2022 Nov;214(Pt 1):113810. doi: 10.1016/j.envres.2022.113810. Epub 2022 Jul 4. PMID: 35798268.
  • Iyer HS, Hart JE, James P, Elliott EG, DeVille NV, Holmes MD, De Vivo I, Mucci LA, Laden F, Rebbeck TR. Impact of neighborhood socioeconomic status, income segregation, and greenness on blood biomarkers of inflammation. Environ Int. 2022 Apr;162:107164. doi: 10.1016/j.envint.2022.107164. Epub 2022 Mar 5. PMID: 35255255; PMCID: PMC8985077.
  • Iyer HS, James P, Valeri L, Bajunirwe F, Nankya-Mutyoba J, Njelekela M, Chiwanga F, Sewram V, Ajayi I, Adebamowo C, Dalal S, Reid TG, Rebbeck TR, Adami HO, Holmes MD. Neighborhood greenness and burden of non-communicable diseases in Sub-Saharan Africa: A multi-country cross-sectional study. Environ Res. 2021 May;196:110397. doi: 10.1016/j.envres.2020.110397. Epub 2020 Oct 31. PMID: 33130166; PMCID: PMC8085185.

Environment

  • Roscoe C, Grady ST, Hart JE, Iyer HS, Manson JE, Rexrode KM, Rimm EB, Laden F, James P. Association between Noise and Cardiovascular Disease in a Nationwide U.S. Prospective Cohort Study of Women Followed from 1988 to 2018. Environ Health Perspect. 2023 Dec;131(12):127005. doi: 10.1289/EHP12906. Epub 2023 Dec 4. PMID: 38048103; PMCID: PMC10695265.
  • Chowdhury-Paulino IM, Hart JE, James P, Iyer HS, Wilt GE, Booker BD, Nethery RC, Laden F, Mucci LA, Markt SC. Association between Outdoor Light at Night and Prostate Cancer in the Health Professionals Follow-up Study. Cancer Epidemiol Biomarkers Prev. 2023 Oct 2;32(10):1444-1450. doi: 10.1158/1055-9965.EPI-23-0208. PMID: 37462694; PMCID: PMC10592318.
  • Leung M, Modest AM, Hacker MR, Wylie BJ, Wei Y, Schwartz J, Iyer HS, Hart JE, Coull BA, Laden F, Weisskopf MG, Papatheodorou S. Traffic-Related Air Pollution and Ultrasound Parameters of Fetal Growth in Eastern Massachusetts. Am J Epidemiol. 2023 Jul 7;192(7):1105-1115. doi: 10.1093/aje/kwad072. PMID: 36963378.
  • DeVille NV, Iyer HS, Holland I, Bhupathiraju SN, Chai B, James P, Kawachi I, Laden F, Hart JE. Neighborhood socioeconomic status and mortality in the nurses’ health study (NHS) and the nurses’ health study II (NHSII). Environ Epidemiol. 2023 Feb;7(1):e235. doi: 10.1097/EE9.0000000000000235. eCollection 2023 Feb. PubMed PMID: 36777531; PubMed Central PMCID: PMC9916023.
  • Leung M, Laden F, Coull BA, Modest AM, Hacker MR, Wylie BJ, Iyer HS, Hart JE, Wei Y, Schwartz J, Weisskopf MG, Papatheodorou S. Ambient temperature during pregnancy and fetal growth in Eastern Massachusetts, USA. Int J Epidemiol. 2023 Jun 6;52(3):749-760. doi: 10.1093/ije/dyac228. PMID: 36495569; PMCID: PMC10244050.
  • Iyer HS, DeVille NV, Stoddard O, Cole J, Myers SS, Li H, Elliott EG, Jimenez MP, James P, Golden CD. Sustaining planetary health through systems thinking: Public health’s critical role. SSM Popul Health. 2021 Jun 11;15:100844. doi: 10.1016/j.ssmph.2021.100844. PMID: 34179331; PMCID: PMC8213960.
  • Iyer HS, James P, Valeri L, Hart JE, Pernar CH, Mucci LA, Holmes MD, Laden F, Rebbeck TR. The association between neighborhood greenness and incidence of lethal prostate cancer: A prospective cohort study. Environ Epidemiology. 2020 Apr 9;4(2):e091. doi: 10.1097/EE9.0000000000000091. PMID: 32656487; PMCID: PMC7319229.
  • Iyer HS, Valeri L, James P, Chen JT, Hart JE, Laden F, Holmes MD, Rebbeck TR. The contribution of residential greenness to mortality among men with prostate cancer: a registry-based cohort study of Black and White men. Environ Epidemiol. 2020 Apr 9;4(2):e087. doi: 10.1097/EE9.0000000000000087. PMID: 32337472; PMCID: PMC7147390.