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Christopher Okunji

Publications

  1. Christopher Okunji, Slavko Komarnytsky, Georgie Fear, Alexander Poulev, David M. Ribnicky, Peter I. Awachie, Yoichiro Ito, and Ilya Raskin. (2007) Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography. J. of Chromatography A, Vol. 1151, Nos. 1-2, pp. 45-50, 2007.

  2. Apollinaire Tsopmo, Pierre Kamnaing, Dieudonn&#233 Ngamga, Pierre Tane, Donna Rattendi, Cyrus Bacchi, Christopher Okunji, Maurice M. Iwu, Brian Schuster, and Olov Sterner. Anti-trypanosomal alkaloids from Xymalos monospora. Nat. Prod. Communications, Vol. 1, No. 8, pp. 619-622, 2006.

  3. Tatsimo, S. J. N., Tane, P., Melissa, J., Sondengam, B. L., Okunji, C. O., Schuster, B. M., Iwu, M. M., and Ikhlas A. Khan. Antimicrobial principle from Aframomum longifolius. Planta Medica, Vol. 72, No. 2, pp. 132-135, 2006.

  4. Chris O. Okunji, Johnson F. Ayafor, Joan E. Jackson, John D. Tally, Cyrus Bacchi, Brian G. Schuster and Maurice M. Iwu. In vitro Antiprotozoal Activity of Quinolone Alkaloids from Araliopsis tabouensis Aubrev & Pellegr. (Rutaceae). Planta Medica, in press.

  5. Chah K. F., Oyeanusi Chika, Dasimaka Deborah, Anaele E. Ngozi, Okunji, C. O., Akubue, P. I., and Iwu, M. M. Antibacterial Activity and Brine Lethality of Some Medicinal Plants of Eastern Nigeria Used as Traditional Remedies for Bacterial Diseases. Journal of Ethnopharmacology, in press.

  6. Wabo, H. K., Tane, P., Connolly, J. D., Okunji, C. O., Schuster, B. M., Iwu, M. M. (2005) Tabouensinium chloride, a novel quaternary pyranoquinoline alkaloid from Araliopsis tabouensis. Nat Prod Res. Sep. 19(6):591-5

  7. Pierre Tane, Christopher O. Okunji, Michel Tchimene, Maurice Iwu and Brian M. Schuster (2005) Antimalarial Natural Products from Some Cameroonian Medicinal Plants. Journal of Cameroon Academy of Sciences Volume 5, 65-76

  8. Okunji, C. O., Akubue, P., Tane, P., Efange, S., Ononiwu, I., Awachie, P., Kyle, D., Milhous, W., Schuster, B., Iwu M., (2005) In vitro Antimalarial Activity of Plants Used in Traditional Medicine in West And Central Africa [MIMCO-512765], ACTA TROPICA, Volume 95, Supplement 1, Page 194

  9. Mbah, J., Tane, P., Ngadjui, B., Connolly, J., Okunji, C., Iwu, M. and Schuster, B. (2005) Antiplasmodial agents from the leaves of Glossocalyx brevipes [MIM-JM-268015], ACTA TROPICA; Volume 95, Supplement 1, Page 193

  10. Tane, P., Wabo, H., Tchimene, M., Okunji, C., Iwu, M., Schuster, B. and Connolly, J. (2005) Lead Antiplasmodial Substances from Some Cameroonian Medicinal Plants [MIM-PT-34914], ACTA TROPICA, Volume 95, Supplement 1, Page 195

  11. Chris O. Okunji, Maurice M. Iwu, Yoichiro Ito, Philip L. Smith (2005) Preparative Separation of Indole Alkaloids from the Rind of Picralima nitida (Stapf) T. Durand & H. Durand by pH-Zone-Refining Countercurrent Chromatography. Journal of Liquid Chromatography & Related Technologies :Volume 28 (5) 775 – 783

  12. Jiang, S., Zeng, Q., Gettayacamin, M., Tungtaeng, A., Wannaying, S., Lim, A., Hansukjariya, P., Okunji, C. O., Zhu, S., Fang, D. (2005) Antimalarial activities and therapeutic properties of febrifugine analogs. Antimicrobial Agents Chemotherapy. Mar; 49(3):1169-76.

  13. C. O. Ezugwu, B. Erdal, D. Chuck, I. A. Khan, C. O. Okunji, B. M. Schuster and M. M. Iwu (2004) Indoloquinazoline alkaloids from Araliopsis tabouensis. Nigerian Journal of Pharmaceutical Research Vol. 3(1) 42-48.

  14. Mbah, J. A., Tane, P., Ngadjui, B. T., Connolly, J. D., Okunji, C. O., Iwu, M. M., Schuster, B. G. (2004) Antiplasmodial Agents from the Leaves of Glossocalyx brevipes. Planta Medica 70(5):437-40.

  15. Christopher, E., Bedir, E., Dunbar, C., Khan, I. A., Okunji, C. O., Schuster, B. M., Iwu, M. M. (2003) Indoloquinazoline alkaloids from Araliopsis tabouensis Helvetica Chimica Acta, 86/8 (2914-2918).

  16. Ngwendson, J. N., Bedir, E., Efange, S. M., Okunji, C. O., Iwu, M. M., Schuster, B. G., Khan, I. A.(2003) Constituents of Peucedanum zenkeri seeds and their antimicrobial effects. Pharmazie 58(8): 587-9.

  17. Okunji, Chris O., Tantalia A. Ware, Rickey P. Hicks, Maurice M. Iwu, David J. Skanchy (2002) Capillary Electrophoresis Determination of Biflavanones from Garcinia kola in Three Traditional African Medicinal Formulations. Planta Medica, May, Vol. 68(5): 440-4.

  18. Okunji, Chris O., Jackson, Joan E., Ayafor, Johnson F., Skanchy, David J., Roth Nancy, Schuster, Brian G., and Iwu, Maurice M. (2000) Antimalarial Potentials of Some Members of the Plant Family Annonaceae, Supplement to the American Journal of Tropical Medicine and Hygiene, Vol. 62(3), 428.

  19. Okunji, Christopher O., Joan E. Jackson, John D. Tally, Nancy Roth, Maurice M. Iwu, Schuster, Brian G. (2000) In vitro antileishmanial and antimalarial activities of 4′,5-Dihydroxy-7-methoxyflavanone from Eupatorium odoratum. Supplement to the American Journal of Tropical Medicine and Hygiene, Vol. 62(3), 396.

  20. Schuster, B. G., Jackson, J. E., Obijiofor, C. N., Okunji, C. O., Milhous, W., Losos, E., Ayafor, J. F., and Iwu, M. M. (1999) Drug development and Conservation of Biodiversity in West and Central Africa: A Model for Collaboration with Indigenous People. Supplement: Pharmaceutical Biology Vol. 37, 84-99.

  21. Tchuendem, M. H., Mbah, J. A., Tsopmo, A., Ayafor, J. F., Sterner, O., Okunji, C. O., Iwu, M. M., Schuster, B. M. (1999) Anti-plasmodial sesquiterpenoids from the African Reneilmia cincinnata. Phytochemistry, Vol. 52(6):1095-1099.

  22. Okunji, C. O., lwu, M. M., Jackson, J. E., Tally, J. D. (1996) Biological Activity of Saponins from Two Dracaena Species. Advances in Experimental Medicine and Biology, Vol. 404: 415-428.

  23. Iwu, M. M., Unaeze, C. N., Okunji, C. O., Corley, D. G., Sanson, D. R., and Tempesta, M. S. (1992) Antibacterial Aromatic Isothiacyanates from the Essential oil of Hippocratea welwitschii Root, Int. J. Crude Drug Research, Vol. 29 (2), 154-158.

  24. Okunji, C. O., Iwu, M. M., and Hostettmann, K. (1991) Molluscicidal Saponins from the Fruit Pulp of Dracaena mannii. Int. J. of Crude Drug Research, Vol. 29 (1), 66-70.

  25. Okunji, C. O., and Iwu, M. M. (1991) Molluscicidal Activity of Garcinia kola Biflavanones. Fitoterapia LXII (1), 74-76.

  26. Ene-Obong, E. E., Nwofia, G. E. and Okunji, C. O. (1991) Depressive Effects of Alcoholic Extracts of Five Molluscicidal Plants on Mitosis. Fitoterapia, LXII (4), 353-356.

  27. Iwu, M. M., Okunji, C. O., Ohiaeri, G. O., Akah, P., Corley D. and Tempesta, M. S. (1990) Dioscortine, The Hypoglycaemic Principle of Dioscorea dumentorum. Planta Medica, Vol. 56 (1), 119-120.

  28. Okunji, C. O., Okeke, C. N., Iwu, M. M., and Gugnani, H. C. (1990) Antifungal Spirostanol Saponin from the Fruit Pulp of Dracaena mannii. Int. J. of Crude Drug Research, Vol. 28 (3), 193-199.

  29. Iwu, M. M., Igboko, O. A., Okunji, C. O., Tempesta, M. S. (1990) Antidiabetic and aldose reductase activities of biflavanones of Garcinia kola. J. Pharm. Pharmacology 42(4): 290-292.

  30. Iwu, M. M., Igboko, A. O., Okunji, C. O., Sanson, D. and Tempesta, M.S. (1990) Antimicrobial Activity and Terpenoids of the Essential oil of Hyptis suaveolens. Int. J. of Crude Drug Research, Vol. 28 (1), 73-76.

  31. Iwu, M. M., Okunji, C. O., Ohiaeri, G. O., Akah, P., Corley, D., and Tempesta, M. S. (1990) Hypoglycaemic Activity of Dioscortine from Tubers of Dioscorea dumentorum in Normal and Alloxan Diabetic Rabbits. Planta Medica, Vol. 56, 264-267.

  32. Okunji, C. O., and Iwu, M. M. (1988) Control of Schistosomiasis using Nigerian Medicinal plants as Molluscicides. Int. J. of Crude Drug Research, Vol. 26 (4), 246-252.

  33. Iwu, M. M., Igboko, A. O., Okunji, C. O., and Onwuchekwa, U. (1987) Evaluation of the Antihepatotoxic activity of the Bioflavonoids of Garcinia kola seeds. J. of Ethnopharmacology, Vol. 21(2), 127-138.

  34. Aguwa, C. N., and Okunji, C. O. (1986) Gastrointestnal Studies of Pyrenacantha staudtii Leaf. J. of Ethnopharmacology, Vol. 15, 45-55.

Books and Chapters in Edited Collections

  1. Maurice M. Iwu, Angela Duncan Diop, Innocent Ononiwu and Christopher O. Okunji. (eds) (2003) Herbal Medicinal Products Used for HIV/AIDS, BDCP Press, Maryland, ISBN 0-9653292-2-4. pp 129

  2. Iwu, M., Duncan Diop, A., Meserole, L., and Okunji, C. (2002) Garcinia kola: A New Look at an Old Adaptogenic Agent. In: Iwu, M. and Wooton, J. (eds.), Advances in Phytomedicine: Vol 1, Ethnomedicine and Drug Development, 191-199. Elsevier, Europe.

  3. Maurice M. Iwu, Angela R. Duncan, Chris O. Okunji (1999) New Antimicrobials of Plant origin New Crops and New Uses, Prospectives in New Crops and New Uses, pp 447-452, ASHS Press, Alexandria, VA.

  4. Okunji, C. O., Jackson, J. E., Tally, J. D., Iwu, M. M., and Schuster, B. G. (1997) Bioassay Approach to Medicinal Plant Research. In: Maurice Iwu, Elijah Sokomba, Chris Okunji, Chioma Obijiofor and Iwe Akubue (eds), Commercial Production of Indigenous Plants as Phytomedicines and Cosmetics. pp. 121-133. BDCP Press Maryland ISBN 0-9653292-0-8

  5. Maurice Iwu, Elijah Sokomba, Chris Okunji, Chioma Obijiofor and Iwe Akubue (eds.), (1997) Commercial Production of Indigenous Plants as Phytomedicines and Cosmetics. BDCP Press, Maryland ISBN 0-9653292-0-8

  6. Okunji, C. 0., Iwu, M. M., Jackson J. E., and Tally, J. D. (1995) Antileishmanial Activity of Some Nigerian Medicinal Plants In: Practiques interculturelles en medecine et sante humaine. pp. 149-160. Prelude edited by Mamadou Sawadogo, Georges Thill Press, Belgique.

Patents and Patent Applications

  • U.S. patent No. 6,403,576 – Antiparasitic and antifungal compositions. Joan E. Jackson, Maurice M. Iwu, Christopher O. Okunji, Cyrus Bacchi, John D. Tally, Johnson F. Ayafor; issued in June 2002.

  • U.S. Patent application 20030157197: Plant-Derived Anti-Parasitic and Antifungal Compounds and Methods of Extracting the Compounds. Christopher O. Okunji, Maurice M. Iwu, Joan E. Jackson, John D. Tally, Cyrus Bacchi, Johnson F. Ayafor; filed 27 October 1999.

  • U.S. Patent application 20030032578: Antifungal and Antiparasitic compounds. Joan E. Jackson, Maurice M. Iwu, Chris O. Okunji, Cyrus Bacchi, John D. Tally, and Johnson F. Ayafor. February 13, 2003.

Invited Plenary Lectures in 2004

  1. Natural Products as Potential Agents in the Control of Water – Related Diseases. (2004) Chris Okunji and Maurice M. Iwu. International Scientific Conference on Water-Related Diseases, April 3 – 10, Abuja, Nigeria

  2. Antimalarial activity of plants used in traditional medicine in West and Central Africa. (2004) Christopher Okunji and Maurice M. Iwu. Plenary presentation at the International Conference on Herbal Medicinal Products for HIV/AIDS, Malaria & Tuberculosis. August 26 – 28, Le Meridien Hotel, Abuja, Nigeria.

  3. Potentials of Cryptolepine and Its Analogues as Antimalarial Compounds. (2004) Ononiwu, I. M., Fakorede, F., Smith, K., Smith, P., Okunji, C. O., Kumar, K. K., Schuster, B. G., Iwu, M. M. Presentation at the International Conference on Herbal Medicinal Products for HIV/AIDS, Malaria & Tuberculosis. August 26 – 28, Le Meridien Hotel, Abuja, Nigeria.

  4. Chemical Standardization of Herbal Medicinal Products Used for HIV/AIDS, Malaria and Tuberculosis. (2004) Christopher Okunji. Presentation at the International Conference on Herbal Medicinal Products for HIV/AIDS, Malaria & Tuberculosis. August 26 – 28, Le Meridien Hotel, Abuja, Nigeria.