Skip to main content

Education

Ph. D. 1992-2000 (Immunology), Department of Human Microbiology, School of Medicine, Tel – Aviv University, Tel – Aviv, Israel. Title of thesis: The mechanism of action of the small GTP-binding protein Rac1 in activating the NADPH oxidase. Thesis advisor: Professor Edgar Pick.
M. S. 1988-1991 (Physiology and Pharmacology), School of Medicine, Tel – Aviv University, Israel. Title of thesis: Interaction of opiates with voltage-dependent sodium channels. Thesis advisor: Professor Yosef Sarne.
B. Ed. 1988-1991 Senior Authorized Teacher of Sport and Physical Education at the Zinnman College of Physical Education, Wingate Institute for Physical Education & Sport, Netanya, Israel.
B. S. 1984-1987 Studies toward the degree of Bachelor of Science in Biology, Faculty of Life Sciences, Tel – Aviv University, Tel – Aviv, Israel.

Senior Swimming Coach 1997-1999 Diploma of Senior Swimming Coach, at the Net Holman School of Coaches and Instructors, Wingate Institute for Physical Education & Sport, Netanya, Israel.
Swimming Coach 1990-1992 Swimming Coach Certificate at the Net Holman School for Coaches & instructors, Wingate Institute for Physical Education & Sport, Netanya, Israel.
Electrician 2002-2004 Studies at the Open University towards “Licensed electrician” diploma. Licensed since 2004.

Academic Work Experience

  • 1997-2006 Lecturer with tenure at Seminar Hakibutzim College, Tel-Aviv and Lecturer at Wingate Institute for Physical Education & Sport, Netanya, Israel.
  • 2002-2006 Head of the Human Body Sciences Laboratory at Seminar Hakibutzim College.
  • 1999-2006 Consultant for physical fitness and healthy nutrition.
  • 1991-1997 Coach and coordinator of swimming instructor course, at the Net Holman School of Coaches and instructors, Wingate Institute for Physical Education & Sport, Netanya, Israel.
  • 1991 Worked part of the year in Ecuador, in US/ Israeli project for the collection and primary analysis of tropical jungle plants used by natives for medicinal and comestible purposes.
  • 1988 Technical analyst at the NASA-Goddard Space Flight Center, Greenbelt, Maryland, USA. Computer analysis of LANDSAT and AVHRR satellites high resolution spectral images and comparison to in-situ surface data for the purpose of calibration of method for the remote determination of the distribution of the reflectance of the earth’s surface.

Teaching Experience

  • 1997-2006 “Exercise Immunology”, “Exercise Physiology”, “General Physiology” and “Anatomy” at the Zinnman College of Physical Education, Wingate Institute for Physical Education & Sport, and at Seminar Hakibutzim college.
  • 2000-2006 Seminar on “Exercise Immunology” at the Zinnman College of Physical Education, Wingate Institute for Physical Education & Sport.
  • 2000-2006 Seminar on “Posture Development” at Seminar Hakibutzim college.
  • 1997-2003 “Swimming” at the Zinnman College of Physical Education, Wingate Institute for Physical Education & Sport, and at Givat Washington College for Physical Education & Sport.
  • 1990-1999 “Exercise physiology” at the Net Holman School of Coaches and Instructors, Wingate Institute for Physical Education & Sport, Netanya, Israel.
  • 1992-1997 Teaching Assistant, “Immunology” at the Department of Human Microbiology, School of Medicine, Tel – Aviv University, Tel – Aviv, Israel.

Publications – Articles

  1. Joseph, G. The Influence of Lessons on Bodily Awareness on the Posture of Children in the Age Range of 3-5 years, 2006, in preparation.
  2. Joseph, G., Tov-Been, D., Duvdevani, A., Wexler, E. The Influence of Moderate Exercise on the Inflammatory and Immune State of Hemodialysis Patients, 2006, in preparation.
  3. Morozov, I., Lotan, O., Joseph, G., Gorzalczany, Y., Pick, E. Mapping of functional domains in p47phox involved in the activation of NADPH oxidase by peptide walking. J. Biol. Chem. 273, 15435-15444, 1998.
  4. Sehr, P., Joseph, G., Genth, H., Just, I., Pick, E., Aktories, K. Glucosylation and ADP-ribosylation of Rho proteins – effects on nucleotide binding, GTPase activity, and effector-coupling. Biochemistry 37, 5296-5304, 1998.
  5. Joseph, G., and Pick, E. Peptide Walking is a novel method for mapping functional domains in proteins. J. Biol. Chem. 270, 29079-29082, 1995.
  6. Joseph, G., Gorzalczany, Y., Koshkin, V., Pick, E. Inhibition of the NADPH oxidase activation by synthetic peptides mapping within the carboxyl-terminal domain of the small GTP-binding proteins. J. Biol. Chem. 269, 29024-29031, 1994.
  7. Bromberg, Y., Shani, E., Joseph, G., Gorzalczany, Y., Sperling, O., Pick, E. The GDP bound form of the small G protein Rac 1 p21 is a potent activator of the superoxide forming NADPH oxidase of macrophage. J. Biol. Chem. 269, 7055-7058, 1994.

Publications – Book Chapters

  • Joseph, G, Dotan, R., Izik, S., Ganot, A. Laboratories in Exercise Physiology, Seminar Hakibutzim College, 2005.
  • Joseph, G. Exercise Physiology, Textbook for Swimming Instructor course, Net Holman School of Coaches and Instructors, Wingate Institute for Physical Education & Sport, Natanya, Israel, (in Hebrew), 1998.

Publications – Abstracts

  1. Tovbin, D., Vexler, E., Margolis, G., Gidron, Y., Duvdevany, A., Avnon, L., Shalev, H., and Joseph, G. Pre-Session Exercise Improves Quality of life of Hospital-based Hemodialysis Patients with High Co-morbidity. ASN Renal Week, San Diego, CA, USA, Nov. 2003.
  2. Joseph, G., Lotan, O., Diatchuk, V., Gorzalczany, Y., Pick, E. Protein-protein interactions in the assembly of the NADPH oxidase from recombinant components. J. Leukoc. Biol. Supp, pp 56, 1996.
  3. Diatchuk, V., Lotan, O., Koshkin, V., Joseph, G., Gorzalczany, Y., Pick, E. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds. Eur. J. Clin. Invest. 26 (supp1):A29, 1996.
  4. Joseph, G., and Pick, E. An undecapeptide corresponding to the near carboxy terminal domain of Rac1 is an inhibitor of macrophage NADPH oxidase. Eur. J. Clin. Invest. 24 (supp2):A33, 1994.

Participation at Professionals Meetings

  • Poster presentation at the Gordon Conference of Phagocytes (New Hampshire, USA, 1998): Morozov, I., Lotan, O., Joseph, G., Gorzalczany, Y., Pick, E. Mapping of functional domains in p47phox involved in the activation of NADPH oxidase by Peptide walking, 1998.
  • Oral presentation (best abstract award) at the Society for Leukocyte Biology and the European Macrophage study group (Verona, Italy, 1996): Joseph, G., Lotan, O., Diatchuk, V., Gorzalczany, Y., Pick, E. Protein-protein interactions in the assembly of the NADPH oxidase from recombinant components, 1996.
  • Poster presentation at the Annual Scientific Meeting of the European Society for Clinical Investigation in 1996: Diatchuk, V., Lotan, O., Koshkin, V., Joseph, G., Gorzalczany, Y., Pick, E. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds, 1996.
  • Oral presentation at the Gordon Conference of Phagocytes (New Hampshire, USA, 1995): Joseph, G. and Pick, E. Peptide Walking is a novel method for mapping functional domains in proteins, 1995.
  • Poster presentation at the Annual Scientific Meeting of the European Society for Clinical Investigation in 1994: Joseph, G., Gorzalczany, Y., Koshkin, V., Pick, E. An undecapeptide corresponding to the near carboxy terminal domain of Rac 1 is an inhibitor of macrophage NADPH oxidase, 1994.

Educational and Professional Honors Awards

  • 2005 Award for Excellence in Teaching at Seminar Hakibutzim college.
  • 1996 Best Abstract Award at the Meeting of the Society for Leukocyte Biology and the European Macrophage study group, 1996, Verona, Italy.
  • 1992-2000 Buchman Scholarship in recognition of excellence in Ph. D. studies.
  • 1988-1991 Excellence in Scholarship Award for M.S. studies.
  • 1985 Award for Excellence in B. S. studies at the Faculty of Life Sciences, Tel – Aviv University.