{"id":750,"date":"2026-06-30T02:29:44","date_gmt":"2026-06-30T02:29:44","guid":{"rendered":"https:\/\/sites.rutgers.edu\/intec\/?page_id=750"},"modified":"2026-06-30T12:16:47","modified_gmt":"2026-06-30T12:16:47","slug":"nih-network","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/intec\/nih-network\/","title":{"rendered":"NIH Network"},"content":{"rendered":"
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In 2023, the National Institutes of Health launched the Transporter Elucidation Network (TEN) <\/span>across four centers. This initiative applies experimental, computational, and translational approaches to 1) identify S<\/u>oL<\/u>ute C<\/u>arrier (SLC) superfamily and A<\/u>TP-b<\/u>inding c<\/u>assette (ABC) transporters in the human placenta, mammary gland, as well at the pediatric brain and intestinal barriers and, 2) characterize their localization, expression, function, and regulation.<\/h5>\n

 <\/p>\n

The Network seeks to identify functional determinants of transporters as gatekeepers of entry to placenta, mammary gland and brain, and applies structural biology, proteomics, metabolomics, organoids, liquid biopsies, and microphysiological systems to this end. Computational strategies, such as machine learning, virtual screening, physiologically-based pharmacokinetics, and perinatal epidemiology complement our experimental approaches.<\/h5>\n
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 <\/p>\n","protected":false},"excerpt":{"rendered":"

In 2023, the National Institutes of Health launched the Transporter Elucidation Network (TEN) across four centers. 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