Development of HSF1 inhibitors
Our new work on the development of an assay and inhibitors for heat shock protein is now available on Med Chem Res. Work done by Geoffrey Chan!
Moschitto Lab
N-hydroxymethylphthalimide for sulfonylation
See our recent preprint on ChemRxiv about a new functionality that can generate sulfinyl radicals from the reduction of N-hydroxymethylphthalimide sulfones. Work by Twinkle Patel, Makalyla Williams and other.
Thesis Defense
Congrtualations to Twinkle on defending her thesis! The first in the lab!
Congratulations Geoff and Makayla
Congratulations to Geoff and Makayla on passing their qualifying exams!
Congratulations Twinkle
Congratulations to Twinkle on passing her independent research proposal and qualifying exam!!
Streamlining SuFEx Inhibitor Development
See our new publication in Angewante Chemie on generating sulfonyl fluorides using photochemistry and a general guide to sulfinate protecting groups. Great job by all!
New Jersey Health Foundation Grant
The Moschitto Group was awarded a grant from the New Jersey Health Foundation to develop Protected Sulfinate Libraries for SuFEx probe development. This is work done by Twinkle and we … Read More
Busch Biomedical Grant
The Moschitto Group was awarded a Busch Biomedical Grant from Rutgers University for work on developing covalent inhibitors and probes of heat shock factor 1 and serine hydroxymethyltransferase. This is … Read More
Sulfonylation of Quinolines
The sulfonylation of quinolines has been published in JOC! Congrats Twinkle! https://pubs.acs.org/doi/full/10.1021/acs.joc.2c02044
PACSFOCS 2022
the group at PACSFOCS 2022