{"id":170,"date":"2017-12-22T18:13:36","date_gmt":"2017-12-22T18:13:36","guid":{"rendered":"http:\/\/sites.rutgers.edu\/professor-example\/?page_id=170"},"modified":"2026-04-21T19:19:00","modified_gmt":"2026-04-21T19:19:00","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/moschitto-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>15. Williams, M.L., Patel, T.I., Moschitto, M.J. 4-Fluorophenyl Tagging as a Diagnostic Tool for Monitoring Sulfur Oxidation States via <sup>19<\/sup>F NMR. <em>Chemrxiv.<\/em> <strong>2<\/strong><strong>026,<\/strong> DO<a href=\"https:\/\/chemrxiv.org\/doi\/full\/10.26434\/chemrxiv.15002220\/v1\">I:10.26434\/chemrxiv.15002220\/v1<\/a><a href=\"https:\/\/doi.org\/10.26434\/chemrxiv.15001625\/v1\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2026\/04\/4tag-toc.png\" alt=\"\" width=\"300\" height=\"190\" \/><\/a><\/p>\n<p>15. Williams, M.L., Patel, T.I., Moschitto, M.J. Electron donor acceptor mediated hydrosulfonylation of olefins from N-hydroxymethylphthamilide sulfones. <em>Chemrxiv.<\/em> <strong>2<\/strong><strong>026,<\/strong> DOI:<a href=\"https:\/\/doi.org\/10.26434\/chemrxiv.15001625\/v1\">26434\/chemrxiv.15001625\/v1<\/a>.<a href=\"https:\/\/doi.org\/10.26434\/chemrxiv.15001625\/v1\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2026\/04\/hydrosulfonylation-1-300x103.png\" alt=\"\" width=\"300\" height=\"190\" \/><\/a>14. Chan, G.H., Moschitto, M.J., Discovery and development of inhibitors of heat shock factor 1 by a fluorescence polarization assay. <em>Med. Chem. Res,<\/em> <strong>2025<\/strong>: DOI: 10.1007\/s00044-025-03513-2.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1007\/s00044-025-03513-2\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2025\/09\/TOC-HSF1-300x190.png\" alt=\"\" width=\"300\" height=\"190\" \/><\/a><\/p>\n<p>13. Patel, T.I., Williams, M.L, Linder, J.M., Shah, S.S., Moschitto, M.J., Sulfonylation of anilines through photocatalytic activation of N-hydroxymethylphthalimide sulfones<em>. ACS Catalysis, <\/em><strong>2026<\/strong><em>, 16, 744\u2212751<\/em>.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1021\/acscatal.5c07507\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2025\/08\/TOC-image-sulfonylation-1.png\" alt=\"\" width=\"497\" height=\"215\" \/><\/a><\/p>\n<p>12.\u00a0 Patel, T.I., Williams, M.L, Chi, Y., Laha, R., Moschitto, M.J., Streamlining SuFEx Inhibitor Development: A Unified Approach Using Photolabile and Orthogonal Sulfinate Protecting Groups. <em>Angew. Chem. Int. Ed. <\/em><strong>2025,<\/strong> e202505984. DOI:10.1002\/anie.202505984<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202505984\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2025\/04\/TOC-image.jpg\" alt=\"\" width=\"500\" height=\"300\" \/><\/a><\/p>\n<p>11. Patel, T.I., Joshi, J.N., Valvezan, A. J., Moschitto M.J.,\u00a0 A Review of Trilaciclib, a first-in-class cyclin-dependent kinase 4\/6 inhibitor, for the management of metastatic small-cell lung cancer. <em>J. Med Chem. Res.<\/em> <strong>2024, <\/strong><em>33<\/em><strong>, <\/strong>1757\u20131768.\u00a0 https:\/\/doi.org\/10.1007\/s00044-024-03288-y<\/p>\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s00044-024-03288-y\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-673\" style=\"border: 3px solid black\" src=\"http:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2024\/07\/Picture2-300x129.png\" alt=\"\" width=\"400\" height=\"172\" srcset=\"https:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2024\/07\/Picture2-300x129.png 300w, https:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2024\/07\/Picture2-768x330.png 768w, https:\/\/sites.rutgers.edu\/moschitto-lab\/wp-content\/uploads\/sites\/288\/2024\/07\/Picture2.png 872w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>10.\u00a0 Patel, T. I Laha, R.; Moschitto, M. J., Synthesis of quinoline silyloxymethylsulfones as intermediates to sulfonyl derivatives. <em>J. Org Chem. <\/em><strong><span class=\"cit-year-info\">2022<\/span><\/strong><em><span class=\"cit-volume\">, 87<\/span><span class=\"cit-issue\">, <\/span><span class=\"cit-pageRange\">15679\u201315683<\/span><\/em>DOI: 10.1021\/acs.joc.2c02044<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.2c02044\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/cms\/10.1021\/acs.joc.2c02044\/asset\/images\/medium\/jo2c02044_0007.gif\" alt=\"\" width=\"500\" height=\"300\" \/><\/a><\/p>\n<p>9. Laha, R.; Patel, T. I.; Moschitto, M. J., Desulfinative Alkylation of Heteroarenes via an Electrostatic Electron Donor-Acceptor Complex. <em>Org. Lett.<\/em> <strong>2022<\/strong>, 24, 7394-7399.\u00a0 DOI:10.1021\/acs.orglett.2c02932<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.2c02932\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/cms\/10.1021\/acs.orglett.2c02932\/asset\/images\/large\/ol2c02932_0008.jpeg\" alt=\"\" width=\"500\" height=\"300\" \/><\/a><\/p>\n<hr \/>\n<hr \/>\n<p>8. Weerawarna, P. M.; Moschitto, M. J.; Silverman, R. B., Theoretical and mechanistic validation of global kinetic parameters of the inactivation of GABA aminotransferase by OV329 and CPP-115.<em> ACS Chem. Biol.<\/em> <strong>2021<\/strong>, <em>16<\/em>, 615-630.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acschembio.0c00784\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/acbcct\/2021\/acbcct.2021.16.issue-4\/acschembio.0c00784\/20210416\/images\/medium\/cb0c00784_0015.gif\" alt=\"\" width=\"500\" height=\"300\" \/><\/a><\/p>\n<hr \/>\n<p>7. Moschitto. M.J., Doubleday, P.F., Catlin. D. S., Kelleher, N. L., Liu, D., Silverman, R. B., \u201cMechanism of action of (1S,3S)-3-amino-4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid, a selective inhibitor of ornithine aminotransferase.\u201d <em>J. Am. Chem. Soc. <\/em><strong>2019<\/strong>, <em>141<\/em>, 10711-10721.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.9b03254\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/jacsat\/2019\/jacsat.2019.141.issue-27\/jacs.9b03254\/20190702\/images\/medium\/ja-2019-03254q_0015.gif\" alt=\"\" width=\"500\" height=\"151\" \/><\/a><\/p>\n<hr \/>\n<p>6. Moschitto. M.J., Silverman R.B. \u201cSynthesis of (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid.\u201d <em>Org. Lett.<\/em> <strong>2018<\/strong>, <em>20<\/em>, 4589-4592.<br \/>\nHighlighted: <em>Synfacts<\/em> <strong>2018<\/strong>; 14(10): 1011.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.orglett.8b01872\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/orlef7\/2018\/orlef7.2018.20.issue-15\/acs.orglett.8b01872\/20180730\/images\/medium\/ol-2018-01872v_0006.gif\" alt=\"\" width=\"500\" height=\"178\" \/><\/a><\/p>\n<hr \/>\n<p>5. Juncosa, J. I. Takaya, K. Le, H. V. Moschitto, M. J. Weerawarna, P. M.; Mascarenhas, R. Liu, D. Dewey, S. L. Silverman, R. B. &#8220;Design and mechanism of (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, a Highly potent \u03b3-aminobutyric acid aminotransferase inactivator for the treatment of addiction.&#8221; <em>J. Am. Chem. Soc. <\/em><strong>2018<\/strong><em>, 140, <\/em>2151\u20132164<em>.<\/em><em><br \/>\n<\/em>Highlighted: <em>Service, R. F. &#8220;<\/em>Chemists seek antiaddiction drugs to battle hijacked brain<em>.&#8221; Science\u00a0 <\/em><strong>2018<\/strong><em>, 360, <\/em>139-140.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/jacs.7b10965\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/jacsat\/2018\/jacsat.2018.140.issue-6\/jacs.7b10965\/20180208\/images\/medium\/ja-2017-10965z_0013.gif\" alt=\"\" width=\"500\" height=\"244\" \/><\/a><\/p>\n<hr \/>\n<p>4. Moschitto, M.J., Lewis, C.A., \u201cSynthesis of the rubiyunnanin B core aglycone&#8221; <em>Eur. J. Org. Chem. <\/em><strong>2016<\/strong>, <em>28, 4773-4777.<\/em><\/p>\n<p><a href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full\/10.1002\/ejoc.201600741\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium\" style=\"border: 3px solid black\" src=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/cms\/asset\/445caed1-9972-410d-8f96-16b542d6cabf\/ejoc201600741-toc-0001-m.jpg\" width=\"906\" height=\"171\" \/><\/a><\/p>\n<hr \/>\n<p>4. Lewis, C.A., Moschitto, M.J., Vaccarello, D.N., \u201cAllylic oxide regio-resolution as a tool for the synthesis and transfer of carbasugars.\u201d <em>Synlett<\/em>, <strong>2015<\/strong>, <em>26<\/em>, 2473\u20132478<em>.<\/em><\/p>\n<hr \/>\n<p>3. Moschitto, M. J<strong>.<\/strong>, Anthony, D. R., and Lewis, C. A., &#8220;Syntheses of arnottin I and arnottin II,&#8221; <em>J. Org. Chem.,<\/em><strong> 2015<\/strong>,<em> 80<\/em>, 3339-3342.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.5b00107\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/joceah\/2015\/joceah.2015.80.issue-6\/acs.joc.5b00107\/20150316\/images\/medium\/jo-2015-00107q_0005.gif\" width=\"500\" height=\"94\" \/><\/a><\/p>\n<hr \/>\n<p>2. Vaccarello, D.N., Moschitto, M.J., Lewis, C.A., \u201cRegiodivergent addition of phenols to allylic oxides.\u201d<em>J. Org. Chem<\/em>., <strong>2015,<\/strong> <em>80<\/em>, 5252-5259.<\/p>\n<p><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.5b00671\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium aligncenter\" style=\"border: 3px solid black\" src=\"https:\/\/pubs.acs.org\/na101\/home\/literatum\/publisher\/achs\/journals\/content\/joceah\/2015\/joceah.2015.80.issue-10\/acs.joc.5b00671\/20150511\/images\/medium\/jo-2015-00671d_0007.gif\" width=\"500\" height=\"72\" \/><\/a><\/p>\n<hr \/>\n<p>1. Moschitto, M. J., Vaccarello, D. N., and Lewis, C. A., &#8220;Regiodivergent addition of phenols to allylic oxides: control of 1,2- and 1,4-additions for cyclitol synthesis,&#8221; <em>Angew. Chem. Int. Ed<\/em>, <strong>2015<\/strong>, <em>54<\/em>, 2142-2145.<strong><em><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/ange.201410228\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium\" style=\"border: 3px solid black\" src=\"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/46781a62-41f6-4f82-80c4-4cc8e92638cd\/mcontent.jpg\" width=\"716\" height=\"110\" \/><\/a><\/em><\/strong><\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<h1>Patents<\/h1>\n<ol reversed=\"\">\n<li>Moschitto, M., Silverman, R. B, U.S. Patent 62\/814026 (May 5, 2019) Process for the synthesis\u00a0 of (S)- 3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid.<\/li>\n<li>Moschitto, M., Silverman R. B., U.S. patent 62\/810018 (February 25<sup>th<\/sup>, 2019) Analogues of 3-amino-4-(propan-2-ylidene) cyclopentane-1-carboxylic acid.<\/li>\n<li>Moschitto, M., Silverman, R. B, U.S. Patent 62\/676373 (May 25, 2018) Process for the synthesis\u00a0 of (S)- 3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>15. Williams, M.L., Patel, T.I., Moschitto, M.J. 4-Fluorophenyl Tagging as a Diagnostic Tool for Monitoring Sulfur Oxidation States via 19F NMR. Chemrxiv. 2026, DOI:10.26434\/chemrxiv.15002220\/v1 15. Williams, M.L., Patel, T.I., Moschitto, &hellip; <a href=\"https:\/\/sites.rutgers.edu\/moschitto-lab\/publications\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":11,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-170","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Publications - Moschitto Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/moschitto-lab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Moschitto Lab\" \/>\n<meta property=\"og:description\" content=\"15. Williams, M.L., Patel, T.I., Moschitto, M.J. 4-Fluorophenyl Tagging as a Diagnostic Tool for Monitoring Sulfur Oxidation States via 19F NMR. Chemrxiv. 2026, DOI:10.26434\/chemrxiv.15002220\/v1 15. 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Williams, M.L., Patel, T.I., Moschitto, M.J. 4-Fluorophenyl Tagging as a Diagnostic Tool for Monitoring Sulfur Oxidation States via 19F NMR. Chemrxiv. 2026, DOI:10.26434\/chemrxiv.15002220\/v1 15. 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