{"id":1294,"date":"2020-04-22T23:58:57","date_gmt":"2020-04-22T23:58:57","guid":{"rendered":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?page_id=1294"},"modified":"2020-04-24T20:15:37","modified_gmt":"2020-04-24T20:15:37","slug":"stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/","title":{"rendered":"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications"},"content":{"rendered":"<p><a href=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-668 alignleft\" src=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png\" alt=\"Joshua Stein thumbnail\" width=\"300\" height=\"225\" srcset=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png 300w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-1024x768.png 1024w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-768x576.png 768w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail.png 1067w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><br \/>\n<a class=\"btn btn-primary\" href=\"https:\/\/rutgers.box.com\/s\/8k9jf7gcv73njrpuuu89myy7253dk1yf\" target=\"_blank\" rel=\"noopener noreferrer\">View video presentation<\/a><\/p>\n<p><strong>Title:<\/strong> Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications<\/p>\n<p><strong>Name:<\/strong> Joshua Stein<\/p>\n<p><strong>Major:<\/strong> Chemistry<\/p>\n<p><strong>School affiliation:<\/strong> School of Arts and Sciences<\/p>\n<p><strong>Programs:<\/strong> Aresty &#8211; Research or Conference Funding Recipient, Dept of Chemistry and Chemical Biology<\/p>\n<p><strong>Other contributors:<\/strong> Yue Sun, Dr. Yanbang Li, Dr. Jianyuan(Jason) Zhang<\/p>\n<p><strong>Abstract:<\/strong> Hydrophobic drug delivery platforms have been an extensive area of study in previous years due to the emergence of new hydrophobic drugs including the widely used chemotherapy medication Paclitaxel. Such targeted delivery is difficult due to the aqueous environment of the human body, and the hydrophobic nature of the drug. In this work, progress towards a novel hydrophobic drug delivery platform is designed and discussed. The drug delivery platform includes selectively adding anilines that contains an alkyne to the top of a C70 cage. The alkyne would undergo a Copper Catalyzed Click Reaction with an azide to attach a water-soluble group. The C70 is then predicted to exhibit amphiphilic behavior by clumping together to create a hydrophobic pocket and a hydrophilic surface. The hydrophobic pocket can store and deliver drugs while the hydrophilic surface can interact with the aqueous environment of the human body, as well as interact with the targeted drug delivery site. This work has many applications towards new methods of developing hydrophobic drug delivery properties that can store and deliver hydrophobic drugs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>View video presentation Title: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications Name: Joshua Stein Major: Chemistry School affiliation: School of Arts and Sciences Programs: Aresty &#8211; Research &hellip; <a href=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":970,"featured_media":0,"parent":441,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1294","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits\" \/>\n<meta property=\"og:description\" content=\"View video presentation Title: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications Name: Joshua Stein Major: Chemistry School affiliation: School of Arts and Sciences Programs: Aresty &#8211; Research &hellip; Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\" \/>\n<meta property=\"og:site_name\" content=\"Senior Exhibits\" \/>\n<meta property=\"article:modified_time\" content=\"2020-04-24T20:15:37+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\",\"name\":\"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits\",\"isPartOf\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage\"},\"thumbnailUrl\":\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png\",\"datePublished\":\"2020-04-22T23:58:57+00:00\",\"dateModified\":\"2020-04-24T20:15:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail.png\",\"contentUrl\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail.png\",\"width\":1067,\"height\":800,\"caption\":\"Joshua Stein thumbnail\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Our Symposium Partners\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Aresty Research Center\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/\",\"name\":\"Senior Exhibits\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/","og_locale":"en_US","og_type":"article","og_title":"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits","og_description":"View video presentation Title: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications Name: Joshua Stein Major: Chemistry School affiliation: School of Arts and Sciences Programs: Aresty &#8211; Research &hellip; Read More","og_url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/","og_site_name":"Senior Exhibits","article_modified_time":"2020-04-24T20:15:37+00:00","og_image":[{"url":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/","name":"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications - Senior Exhibits","isPartOf":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage"},"image":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage"},"thumbnailUrl":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail-300x225.png","datePublished":"2020-04-22T23:58:57+00:00","dateModified":"2020-04-24T20:15:37+00:00","breadcrumb":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#primaryimage","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail.png","contentUrl":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Josh_Stein_researchposter_thumbnail.png","width":1067,"height":800,"caption":"Joshua Stein thumbnail"},{"@type":"BreadcrumbList","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/stein-joshua-synthesis-of-an-amphiphilic-c70-fullerene-derivative-for-biomedical-applications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/"},{"@type":"ListItem","position":2,"name":"Our Symposium Partners","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/"},{"@type":"ListItem","position":3,"name":"Aresty Research Center","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/aresty-research-virtual-symposium-2020\/"},{"@type":"ListItem","position":4,"name":"Stein, Joshua: Synthesis of an Amphiphilic C70 Fullerene Derivative for Biomedical Applications"}]},{"@type":"WebSite","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/","name":"Senior Exhibits","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/1294"}],"collection":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/users\/970"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/comments?post=1294"}],"version-history":[{"count":4,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/1294\/revisions"}],"predecessor-version":[{"id":1473,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/1294\/revisions\/1473"}],"up":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/441"}],"wp:attachment":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/media?parent=1294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}