{"id":1603,"date":"2020-04-28T21:24:59","date_gmt":"2020-04-28T21:24:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?page_id=1603"},"modified":"2020-04-28T21:29:33","modified_gmt":"2020-04-28T21:29:33","slug":"titova-elizabeth","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/titova-elizabeth\/","title":{"rendered":"Titova, Elizabeth: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells"},"content":{"rendered":"

\"\"<\/a><\/p>\n

View video presentation<\/a><\/strong><\/p>\n

Title:<\/strong> MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells<\/p>\n

Name:<\/strong> Elizabeth Titova<\/p>\n

Major:<\/strong> Biological Sciences<\/p>\n

School affiliation:<\/strong> School of Environmental and Biological Sciences<\/p>\n

Programs:<\/strong> Aresty – RA Program<\/p>\n

Other contributors:<\/strong> Sierra Triolo, Joshua Jose, Reynold A. Panettieri, Jr., and Cynthia Koziol-White<\/p>\n

Abstract:<\/strong> : Asthma is a disease characterized by inflammation, reversible airflow obstruction, and increased airway hyperresponsiveness. Inhaled corticosteroids are a mainstay treatment for asthma, with a proportion of the severe asthma population becoming refractory to this treatment. Mechanisms underlying how corticosteroids modulate the contractile status of airways remain largely unknown. Previously, we found that steroid treatment of HASM resulted in alterations in histone acetylation and gene expression, potentially modulating contractile gene expression. Given these data, we hypothesized that inhibition of the histone acetyltransferase males absent on
\nthe first (MOF) will modulate contractile signaling in HASM.<\/p>\n","protected":false},"excerpt":{"rendered":"

View video presentation Title: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells Name: Elizabeth Titova Major: Biological Sciences School affiliation: School of Environmental and Biological Sciences … Read More<\/a><\/p>\n","protected":false},"author":970,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1603","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nTitova, Elizabeth: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells - Senior Exhibits<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/titova-elizabeth\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Titova, Elizabeth: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells - Senior Exhibits\" \/>\n<meta property=\"og:description\" content=\"View video presentation Title: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells Name: Elizabeth Titova Major: Biological Sciences School affiliation: School of Environmental and Biological Sciences … Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/titova-elizabeth\/\" \/>\n<meta property=\"og:site_name\" content=\"Senior Exhibits\" \/>\n<meta property=\"article:modified_time\" content=\"2020-04-28T21:29:33+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/04\/Elizabeth_Titova_thumbnail-300x225.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/titova-elizabeth\/\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/titova-elizabeth\/\",\"name\":\"Titova, Elizabeth: MG149 Inhibits Agonist-induced Contractile Signaling in Human Airway Smooth Muscle (HASM) Cells - 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