{"id":3243,"date":"2020-08-12T03:22:05","date_gmt":"2020-08-12T03:22:05","guid":{"rendered":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?page_id=3243"},"modified":"2020-08-12T04:04:58","modified_gmt":"2020-08-12T04:04:58","slug":"nguyen-my","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/","title":{"rendered":"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity"},"content":{"rendered":"<p><a href=\"https:\/\/rutgers.box.com\/s\/3q3aenv0upoxm1ztdjnm763vcxa7qmgt\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-3169 alignleft\" src=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png\" alt=\"\" width=\"300\" height=\"212\" srcset=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png 300w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-1024x724.png 1024w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-768x543.png 768w, https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail.png 1132w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><strong><a class=\"btn btn-primary\" href=\"https:\/\/rutgers.box.com\/s\/ox1up9sbc1e3ggi1e4hgq6yq6mveblp3\" target=\"_blank\" rel=\"noopener noreferrer\">View video presentation<\/a><\/strong><\/p>\n<p><strong>Title:<\/strong> Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity<\/p>\n<p><strong>Name:<\/strong> My Nguyen<\/p>\n<p><strong>Major:<\/strong> Cell Biology and Neuroscience<\/p>\n<p><strong>School affiliation:<\/strong> School of Arts and Sciences<\/p>\n<p><strong>Programs:<\/strong> Division of Life Sciences Summer Undergraduate Research Fellowship (DLS-SURF)<\/p>\n<p><strong>Other contributors:<\/strong> Ivan Linares, Grayson Sipe, and Rafiq Huda<\/p>\n<p><strong>Abstract:<\/strong> Alcohol use disorder is characterized by loss of control over drinking behavior and increase in the amount of alcohol intake over time despite adverse consequences. Although much work has been done examining how cortical circuits change with models of binge-like drinking, the acute effects of alcohol consumption on neuronal physiology and the coupling between brain states remain unknown. Here, we examine the changes in pupil diameter and activity of corticostriatal neurons in the anterior cingulate cortex (ACC) using two-photon calcium imaging as head-fixed mice actively drank alcohol over days. Striatal projecting and unlabeled cells were recorded concurrently with licking behavior and pupillometry to approximate changes in arousal. We find that alcohol consumption differentially affects distinct cortical projection neurons. Interestingly, alcohol drinking alters both labeled and unlabeled excitatory neurons\u2019 correlations with pupil dynamics over time. In the future, we plan to examine how alcohol affects different neuromodulatory transmitter systems and interneurons on regulating cortical excitability. We are interested in knowing whether corticostriatal neurons are specialized for changes in pupil-neural activity correlations during drinking.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>View video presentation Title: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity Name: My Nguyen Major: Cell Biology and Neuroscience School affiliation: School of Arts and &hellip; <a href=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":970,"featured_media":0,"parent":3239,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3243","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits\" \/>\n<meta property=\"og:description\" content=\"View video presentation Title: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity Name: My Nguyen Major: Cell Biology and Neuroscience School affiliation: School of Arts and &hellip; Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\" \/>\n<meta property=\"og:site_name\" content=\"Senior Exhibits\" \/>\n<meta property=\"article:modified_time\" content=\"2020-08-12T04:04:58+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\",\"name\":\"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits\",\"isPartOf\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage\"},\"thumbnailUrl\":\"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png\",\"datePublished\":\"2020-08-12T03:22:05+00:00\",\"dateModified\":\"2020-08-12T04:04:58+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail.png\",\"contentUrl\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail.png\",\"width\":1132,\"height\":800},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Our Symposium Partners\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Division of Life Sciences (DLS) Summer Fellowship Program\",\"item\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website\",\"url\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/\",\"name\":\"Senior Exhibits\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/","og_locale":"en_US","og_type":"article","og_title":"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits","og_description":"View video presentation Title: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity Name: My Nguyen Major: Cell Biology and Neuroscience School affiliation: School of Arts and &hellip; Read More","og_url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/","og_site_name":"Senior Exhibits","article_modified_time":"2020-08-12T04:04:58+00:00","og_image":[{"url":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/","name":"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity - Senior Exhibits","isPartOf":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage"},"image":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage"},"thumbnailUrl":"http:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail-300x212.png","datePublished":"2020-08-12T03:22:05+00:00","dateModified":"2020-08-12T04:04:58+00:00","breadcrumb":{"@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#primaryimage","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail.png","contentUrl":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-content\/uploads\/sites\/442\/2020\/08\/my-nguyen-poster_thumbnail.png","width":1132,"height":800},{"@type":"BreadcrumbList","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/nguyen-my\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/"},{"@type":"ListItem","position":2,"name":"Our Symposium Partners","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/"},{"@type":"ListItem","position":3,"name":"Division of Life Sciences (DLS) Summer Fellowship Program","item":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/partners\/dls-division-of-life-sciences\/"},{"@type":"ListItem","position":4,"name":"Nguyen, My: Alcohol Consumption Affects the Coupling between Brain State and Prefrontal Cortical Activity"}]},{"@type":"WebSite","@id":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/#website","url":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/","name":"Senior Exhibits","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/3243"}],"collection":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/users\/970"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/comments?post=3243"}],"version-history":[{"count":5,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/3243\/revisions"}],"predecessor-version":[{"id":3245,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/3243\/revisions\/3245"}],"up":[{"embeddable":true,"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/pages\/3239"}],"wp:attachment":[{"href":"https:\/\/sites.rutgers.edu\/nb-senior-exhibits\/wp-json\/wp\/v2\/media?parent=3243"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}