Publications

Pathological Mechanisms of Motor Dysfunction in Familial Danish Dementia: Insights from a Knock-In Rat Model.Arnab Choudhury, Metin Yesiltepe, Tammaryn Lashley, Vishal Singh, Tao Yin, Anllely Fernandez, Luciano D’Adamio, Hyung Jin Ahn (2025). BioRxiv.

Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease.Vishal Singh, Arnab Choudhury, Hyung Jin Ahn (2025). Neural Regeneration Research 20(1):p 203-204, January 2025. PMID: 39657091.

Caveolin-1 and Aquaporin-4 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Hereditary Cerebral Amyloid Angiopathy.Vishal Singh, Nicholas Rochakim, Francesca Ferraresso, Arnab Choudhury, Christian J Kastrup, Hyung Jin Ahn (2024). BioRxiv. PMID: 39605467.

Fiberoptic hemodynamic spectroscopy reveals abnormal cerebrovascular reactivity in a freely moving mouse model of Alzheimer’s disease. Daniel S Gareau, Nicholas RochaKim, Arnab Choudhury, Michael Bamkole, Matija Snuderl, Julia Zou, Anna Yaroslavsky, Steven L Jacques, Sidney Strickland, James G Krueger, Hyung Jin Ahn (2023). Frontier Mol. Neurosci, Volume 16 – 2023. PMID: 37465366.

Striatal fibrinogen extravasation and vascular degeneration correlate with motor dysfunction in an aging mouse model of Alzheimer’s disease. Hanna E Berk-Rauch, Arnab Choudhury, Allison T Richards, Pradeep K Singh, Zu-Lin Chen, Erin H Norris, Sidney Strickland, Hyung Jin Ahn (2023). Frontier. Aging Neurosci, Volume 15 – 2023. PMID: 36967821.

Vascular endothelial growth factor associated dissimilar cerebrovascular phenotypes in two different mouse models of Alzheimer’s Disease. Nicholas M. Tataryn, Vishal Singh, Jonathan P. Dyke, Hanna E. Berk-Rauch, Dana Clausen, Eric Aronowitz, Erin H. Norris, Sidney Strickland, Hyung Jin Ahn (2021). Neurobiology of Aging Volume 107, November 2021, Pages 96-108. PMID: 34416494.

Cerebral amyloid angiopathy-linked β-amyloid mutations promote cerebral fibrin deposits via increased binding affinity for fibrinogen. Steven A. Cajamarca, Erin H. Norris, Louise van der Weerd, Sidney Strickland, Hyung Jin Ahn (2020). PNAS Volume 117 (25) 14482-14492. PMID: 32518112.

Inflaming the Brain Hyung Jin Ahn, Sarah K. Baker, Erin H. Norris, Sidney Strickland (2019) “Inflaming the Brain.” (2019). Neuron, Volume 101:991-993. PMID: 30897363.

Analysis of beta-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy. Pradeep K. Singh, Hanna E. Berk-Rauch, Nadine Soplop, Kunihiro Uryu, Sidney Strickland, Hyung Jin Ahn (2018). JoVE, 2018 Nov 30:(141):10.3791/58475. PMID: 30582601.

Aminopyrimidine Class Aggregation Inhibitor Effectively Blocks Abeta-Fibrinogen Interaction and Abeta-Induced Contact System Activation. Pradeep K. Singh, Masanori Kawasaki, Hanna E. Berk-Rauch, Michael A. Foley, Erin H. Norris, Sidney Strickland, Kazuyoshi Aso, Hyung Jin Ahn (2018). ACS Vol 57/Issue 8. PMID: 29394041.

Interactions of Beta-Amyloid Peptide with Fibrinogen and Coagulation Factor XII may contribute to Alzheimer’s Disease. Hyung Jin Ahn, Zu-Lin Chen, Daria Zamolodchikov, Erin H. Norris, Sidney Strickland (2017). Current Opinion in Hematology 24(5):p 427-431, September 2017. PMID: 28661939.

Biochemical and Structural Analysis of the Interaction between Beta-Amyloid and Fibrinogen. Daria Zamolodchikov, Hanna E. Berk-Rauch, Deena A. Oren, Daniel S. Stor, Pradeep K. Singh, Kazuyoshi Aso, Sidney Strickland, Hyung Jin Ahn (2016). Blood (2016) 128 (8): 1144–1151. PMID: 27389717.

A novel Abeta-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice. Hyung Jin Ahn, Fraser Glickman, Kai Lai Poon, Daria Zamolodchikov, Odella C. Jno- Charles, Erin H. Norris, Sidney Strickland (2014). Exp Med (2014) 211 (6): 1049–1062. PMID: 24821909.

Optical Fiber Spectroscopy Measures Perfusion of the Brain in a Murine Alzheimer’s Disease Model Hyung Jin Ahn, Sidney Strickland, James Krueger, Daniel Gareau (2014). Proceedings of the SPIE, Volume 8938, id. 89380Q 6 pp. (2014).

The Alzheimer’s Disease peptide Beta-Amyloid Interacts with Fibrinogen and Induces its Oligomerization Hyung Jin Ahn, Daria Zamolodchikov, Marta Cortes-Canteli, Erin H. Norris, J. Fraser Glickman, Sidney Strickland (2010). PNAS 107 (50) 21812-21817. PMID: 21098282.

Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer’s disease. Marta Cortes-Canteli, Justin Paul, Erin H. Norris, Robert Bronstein, Hyung Jin Ahn, Daria Zamolodchikov, Shivaprasad Bhuvanendran, Katherine M. Fenz, Sidney Strickland (2010). Neuron Volume 66, Issue 5, 10 June 2010, Pages 695-709. PMID: 20547128.

c-Rel, an NF-κB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation. Hyung Jin Ahn, Cateria Hernandez, Jonathan M. Levenson, Farah Lubin, Hsiou-Chi Liou, J. David Sweatt (2008). Learn. Mem. 2008. 15: 539-549. PMID: 18626097.