{"id":1505,"date":"2023-12-22T00:00:53","date_gmt":"2023-12-22T00:00:53","guid":{"rendered":"https:\/\/sites.rutgers.edu\/precision-medicine\/?p=1505"},"modified":"2023-12-22T05:16:14","modified_gmt":"2023-12-22T05:16:14","slug":"intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles","status":"publish","type":"post","link":"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/","title":{"rendered":"IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles"},"content":{"rendered":"<p><strong>Our latest article published in Bioinformatics (Oxford)<\/strong> i.e.,<\/p>\n<p><strong><em>IntelliGenes<\/em>: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles.<\/strong><\/p>\n<p>In this article, we present <em>IntelliGenes<\/em>, a novel machine learning (ML) pipeline for the multi-genomics exploration to discover biomarkers significant in disease prediction with high accuracy. <em>IntelliGenes<\/em> is based on a novel approach, which consists of nexus of conventional statistical techniques and cutting-edge ML algorithms using multi-genomic, clinical, and demographic data. <em>IntelliGenes<\/em> introduces a new metric i.e., Intelligent Gene (I-Gene) score to measure the importance of individual biomarkers for prediction of complex traits. I-Gene scores can be utilized to generate I-Gene profiles of individuals to comprehend the intricacies of ML used in disease prediction. <em>IntelliGenes<\/em> is user-friendly, portable, and a cross-platform application, compatible with Microsoft Windows, macOS, and UNIX operating systems. <em>IntelliGenes<\/em> not only holds the potential for personalized early detection of common and rare diseases in individuals, but also opens avenues for broader research using novel ML methodologies, ultimately leading to personalized interventions and novel treatment targets.<\/p>\n<p><strong>Publication:<\/strong><\/p>\n<ul>\n<li>Degroat, W., Mendhe, D., Bhurasi, A., Abdelhalim, H., Saman, Z., &amp; <strong>Ahmed, Z.*<\/strong> (2023). <strong><a href=\"https:\/\/academic.oup.com\/bioinformatics\/advance-article\/doi\/10.1093\/bioinformatics\/btad755\/7473370?searchresult=1\" target=\"_blank\" rel=\"noopener\"><em>IntelliGenes<\/em>: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles<\/a>.<\/strong> Bioinformatics. btad755. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38096588\/\" target=\"_blank\" rel=\"noopener\">PMID: 38096588<\/a>. (Oxford).<\/li>\n<\/ul>\n<p><em>\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our latest article published in Bioinformatics (Oxford) i.e., IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles. In this article, we present IntelliGenes, a &hellip; <a href=\"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/\" class=\"\">Read More<\/a><\/p>\n","protected":false},"author":1800,"featured_media":1506,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[23,15,17],"tags":[],"class_list":["post-1505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ai-ml","category-precision-medicine","category-publication"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles - Precision Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles - Precision Medicine\" \/>\n<meta property=\"og:description\" content=\"Our latest article published in Bioinformatics (Oxford) i.e., IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles. In this article, we present IntelliGenes, a &hellip; Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/\" \/>\n<meta property=\"og:site_name\" content=\"Precision Medicine\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-22T00:00:53+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-22T05:16:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sites.rutgers.edu\/precision-medicine\/wp-content\/uploads\/sites\/701\/2023\/12\/intelligenes_banner_1705.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1636\" \/>\n\t<meta property=\"og:image:height\" content=\"503\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Zeeshan Ahmed\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Zeeshan Ahmed\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/\",\"url\":\"https:\/\/sites.rutgers.edu\/precision-medicine\/intelligenes-a-novel-machine-learning-pipeline-for-biomarker-discovery-and-predictive-analysis-using-multi-genomic-profiles\/\",\"name\":\"IntelliGenes: A novel machine learning pipeline for biomarker discovery and predictive analysis using multi-genomic profiles - 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