Dr. Mani has been providing clinical care for patients with epilepsy since 2004. He had more than 15 years of experience in advanced epilepsy, EEG, clinical neurophysiology and other neurology patient care & clinical research trials and other studies.
He has specialized research training in Epilepsy and Neurophysiology; Clinical Trials & Therapeutics; Epidemiology and Biostatistics.
He takes care of patients in the full spectrum of seizure & epilepsy severity — those dealing with optimal management of their first seizure to those with years of uncontrolled epilepsy or medication side effects. His goal is improvement of the lives of his patients by providing scientific-based and state-of-the-art medications, safe & effective necessary surgeries, neuro-stimulation devices, and non-medication management.
He serves as Division Chief for Rutgers RWJMS Adult Epilepsy; Medical Director of the RWJUH New Brunswick Clinical Neurophysiology Lab; Fellowship Director for the Rutgers RWJMS Epilepsy Fellowship.
He directs our NAEC Level 4 Multi-disciplinary Epilepsy Center Team (FOR ADULT AND PEDIATRIC PATIENTS), leads and participate in several national and worldwide clinical trials, and collaborates with other leading Epilepsy Centers & researchers to give his patients the best outcomes.
He has won NJ Best Physician Awards; been awarded NIH Research Funding & Awards; and has worked with medical researchers to lead and participate in numerous epilepsy clinical trials. Trials allow NJ patients to receive greater access to cutting-edge medications and other interventions for epilepsy.
He has Board Certifications in Epilepsy, EEG Monitoring, Neurophysiology, and Neurology.
He serves as Director of Quality & Safety for the Rutgers RWJMS Department of Neurology.
He serves as Director for the Inpatient General Neurology Consultation Service at RWJUH New Brunswick.
He has served as Associate Director of the Rutgers RWJMS Neurology Clerkship to educate hundreds of medical students and other neurologists per year in NJ.
Dr. Mani’s formal training includes: a BA (Molecular Biology & Biochemistry; Psychology & Behavioral Neuroscience; more at Rutgers College in New Brunswick, NJ); MD (Dartmouth Medical School; Geisel School of Medicine); Medical Internship (Lahey Clinic Medical Center, Tufts); Neurology Residency (Tufts Medical Center; rotations at Childrens Hospital of Boston); Fellowship in Epilepsy, Neurophysiology & Research Degree (Hospital of the University of Pennsylvania; including rotations at Childrens Hospital of Pennsylvania). He continues to stay up-to-date with regular professional conferences and more, and he contributes to writing and lecturing to educate other doctors and providers.
He has been part of Robert Wood Johnson New Brunswick since 2011.
Education/Training:
- Undergraduate School – Rutgers University
- Medial School – Dartmouth Geisel School of Medicine
- Internship – Tufts Medical Center
- Residency – Tufts Medical Center (including rotations at Boston Children’s Hospital)
- Fellowship (Epilepsy, Neurophysiology, & Clinical Research) – Hospital of the University of Pennsylvania (including rotations at Children’s Hospital of Philadelphia)
Ongoing Research Trials & Studies for Patients with Epilepsy:
Pivotal-Safety and Therapeutic Measures of Transcranial Direct Current Stimulation (tDCS) in Patients With Refractory Focal Epilepsy
This is a clinical trial consisting of 10 clinic-based sessions a short treatment with non-invasive electric stimulation through the scalp for eligible patients with focal epilepsy 9 years old and greater with seizures not medically-controlled.
https://clinicaltrials.gov/study/NCT04770337?term=Neuroelectrics%20Corporation&rank=2
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures
This is a clinical trial of a home-administered inhaled version of alprazolam to terminate seizures that are prolonged in patients more than 12 years old with focal or generalized seizures remaining uncontrolled.
https://clinicaltrials.gov/study/NCT05077904?term=ucb%20staccato&rank=2
Changes in the Brain in Patients with Epilepsy after Traumatic Brain Injury
https://www.haisunlab.com/research
Please use the Contact Form linked at the top of the webpage to give your information (including a phone number) if interested in any of the research studies.
Ram Mani Publication Highlights:
- Mani R, Almelegy A, Truong TM, Pathak, GN, Wagner ML, Wassef C. Distinguishing benign rashes from severe skin reactions from anti-seizure medications. Current Treatment Options In Neurology. Vol 26, pp 115-138. 21 March 2024.
- Kamitaki BK, Janmohamed M, Kandula P, Elder C, Mani R, Wong S, Peucca P, O’Brien TJ, Lin H, Heiman GA, Choi H. Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy. Epilepsia, Oct 2021. https://pubmed.ncbi.nlm.nih.gov/34705264/
- Scharf, M.T., Greenberg, P., Wong, S., Mani R. Obstructive sleep apnea risk in patients with focal versus generalized epilepsy. Epilepsy and Behavior, 111, Oct 2020. https://pubmed.ncbi.nlm.nih.gov/32534421/
- Mani R, Monteleone C, Schalock PC, Truong T, Zhang XB, Wagner ML. Rashes and other hypersensitivity reactions associated with antiepileptic drugs: A review of current literature. Seizure. 2019 Oct;71:270-278. https://pubmed.ncbi.nlm.nih.gov/31491658/
- Wong S, Mani R, Danish S. Comparison and Selection of Current Implantable Anti-Epileptic Devices. Neurotherapeutics. Volume 16, Issue 2, 15 April 2019, Pages 369-380. https://pubmed.ncbi.nlm.nih.gov/31062294/
- Kamitaki BK, Yum A, Lee J, Rishty S, Sivaraaman K, Esfahanizadeh A, Mani R, Wong S. Yield of conventional and automated seizure detection methods in the epilepsy monitoring unit. Seizure. 2019 Jul;69:290-295.
- Attiah MA, Paulo DL, Danish SF, Stein SC, Mani R. Anterior temporal lobectomy compared with laser thermal hippocampectomy for mesial temporal epilepsy: a threshold analysis study. Epilepsy Res. 2015 Sep; 115:1-7. PMID 26220371.
For Patient Appointments:
Call 732-235-7733
For non-urgent research matters, Dr. Mani’s team can be emailed at the following secure address.
Please note that people will be called back typically within 1-week.
Email: rwj.epilepsy@rutgers.edu
RWJBH MyChart is the preferred web-portal for patient communication. Info:
https://mychart.rwjbh.org/MyChart/Authentication/Login?