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We are a bunch of curiosity driven, fun, and coffee loving scientists who seek to understand how mRNAs are stored at specific sites in cells and get translated upon exposure to certain signals.

Collectively, our previous research has shown that unlike previously thought, stress granules [SGs] are present in axons under physiological conditions to store non-translating pools of axonal mRNAs and act as a negative regulator of axon regeneration. This finding suggests that SGs potentially play important roles during normal physiological conditions.

In our lab we aim to test this hypothesis using neuronal development as a model system and further assess how/if impaired SGs play any role in axon regeneration post Spinal Cord Injury, in Neurodevelopmental Disorders, and in Neurodegenerative Diseases.