Happy to share our latest research published in eBioMedicine!
What we did: We used historical data and specimens from the Mothers and Children Cohort Study (MICS) to study how HIV infection affects DNA methylation profiles in the context of no antiretroviral therapy (ART) in infants at 3 and 12 months of age. This study was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (R21HD104558).
Key finding: HIV infection is associated with the infant epigenome in the absence of ART. In utero HIV exposure in the absence of infection did not have an effect on the infant epigenome.
Read the full paper here: https://lnkd.in/eFTWidEw
(Douglas et al., eBioMedicine, 2025)
This was a collaborative effort led by Rutgers School of Public Health alumni Jasmine Douglas, Ziyi Wang, and Francesca Zumpano, with collaborators Jaya Satagopan, Jack Moye, Stephen Arpadi, Carmen Marsit, and Emily Barrett!