{"id":363,"date":"2020-07-09T16:51:59","date_gmt":"2020-07-09T16:51:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/tina-liu-lab\/?page_id=363"},"modified":"2026-03-01T22:43:41","modified_gmt":"2026-03-01T22:43:41","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/tina-liu-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"
2026<\/h5>\n

Programmable kinetic barcoding for multiplexed RNA detection with Cas13a.\u00a0S. <\/span>Son<\/span><\/span>, A. <\/span>Lyden<\/span><\/span>, C.F.<\/span> Ng<\/span><\/span>, A. Dextre<\/span><\/span>, J.\u00a0Shu<\/span><\/span>, S.I.<\/span> Stephens<\/span><\/span>, P. <\/span>Fozouni<\/span><\/span>, G.<\/span>J.<\/span> Knott<\/span><\/span>, D.C.J.<\/span> Smock<\/span><\/span>, T.Y.<\/span> Liu<\/span><\/span><\/strong>, D. Boehm<\/span><\/span>, C. <\/span>Simoneau<\/span><\/span>, G.R. <\/span>Kumar<\/span><\/span>, J.A.<\/span> Doudna<\/span><\/span>, M.<\/span>\u00a0Ott<\/span><\/span>, D.<\/span>A.<\/span> Fletcher. Accepted Feb 2026, Nature Biomedical Engineering.<\/em><\/span><\/span><\/span><\/p>\n

2025<\/h5>\n

Programmable kinetic barcoding for multiplexed RNA detection with Cas13a.<\/a>\u00a0S. <\/span>Son<\/span><\/span>, A. <\/span>Lyden<\/span><\/span>, C.F.<\/span> Ng<\/span><\/span>, A. Dextre<\/span><\/span>, J.\u00a0Shu<\/span><\/span>, S.I.<\/span> Stephens<\/span><\/span>, P. <\/span>Fozouni<\/span><\/span>, G.<\/span>J.<\/span> Knott<\/span><\/span>, D.C.J.<\/span> Smock<\/span><\/span>, T.Y.<\/span> Liu<\/span><\/span><\/strong>, D. Boehm<\/span><\/span>, C. <\/span>Simoneau<\/span><\/span>, G.R. <\/span>Kumar<\/span><\/span>, J.A.<\/span> Doudna<\/span><\/span>, M.<\/span>\u00a0Ott<\/span><\/span>, D.<\/span>A.<\/span> Fletcher. medRxiv\u00a0<\/em>[preprint]. doi:<\/span> https:\/\/doi.org\/10.1101\/2025.07.03.25328829.<\/span><\/span><\/span><\/span><\/p>\n

2022<\/h5>\n

Rapid detection of SARS-CoV-2 RNA in saliva via Cas13.<\/a> S.S. Chandrasekaran*, S. Agrawal*, A. Fanton*, A.R. Jangid, B. Charrez, A.M. Escajeda, S. Son, R. McIntosh, H. Tran, A. Bhuiya, M.D. de Le\u00f3n Derby, N.A. Switz, M. Armstrong, A.R. Harris, N. Prywes, M. Lukarska, S.B. Biering, D.C.J. Smock, A. Mok, G.J. Knott, Q. Dang, E. Van Dis, E. Dugan, S. Kim, T.Y. Liu<\/b>; IGI Testing Consortium; Moehle EA, Kogut K, Eskenazi B, Harris E, Stanley SA, L.F. Lareau, M.X. Tan, D.A. Fletcher, J.A. Doudna, D.F. Savage, P.D. Hsu. Nat Biomed Eng.<\/em> 6(8):944-956. PMID: 35953650. **Featured on the cover of Nature Biomedical Engineering. Innovative Genomics Institute press release: Link<\/a>
\n<\/em><\/strong><\/p>\n

2021<\/h5>\n

Sensitive and multiplexed RNA detection with Cas13 droplets and kinetic barcoding.<\/a> S. Son, A. Lyden, J. Shu, S.I. Stephens, P. Fozouni, G.J. Knott, D.C.J. Smock, T.Y. Liu<\/b>, D. Boehm, C. Simoneau, R. Kumar, J.A. Doudna, M. Ott, D.A. Fletcher. medRxiv<\/em> [Preprint].<\/p>\n

Accelerated RNA detection using tandem CRISPR nucleases.<\/a> T.Y. Liu<\/b>, G.J. Knott, D.C.J. Smock, J.J. Desmarais, S. Son, A. Bhuiya, S. Jakhanwal, N. Prywes, S. Agrawal, M. D\u00edaz de Le\u00f3n Derby, N.A. Switz, M. Armstrong, A.R. Harris, E.J. Charles, B.W. Thornton, P. Fozouni, J. Shu, S.I. Stephens, G.R. Kumar, C. Zhao, A. Mok, A.T. Iavarone, A.M. Escajeda, R. McIntosh, S. Kim, E.J. Dugan; IGI Testing Consortium, K.S. Pollard, M.X. Tan, M. Ott, D.A. Fletcher, L.F. Lareau, P.D. Hsu, D.F. Savage, J.A. Doudna. Nat Chem Biol.<\/em> 17(9), 982\u2013988. PMID: 34354262\u00a0\u00a0 **Featured on the cover of Nature Chemical Biology. <\/em><\/strong>UC Berkeley press release: <\/em><\/strong>Link<\/strong><\/em><\/a><\/p>\n

Rapid, point-of-care molecular diagnostics with Cas13.<\/a> S. Agrawal*, A. Fanton*, S.S. Chandrasekaran*, B. Charrez, A.M. Escajeda, S. Son, R. Mcintosh, A. Bhuiya, M.D. de Le\u00f3n Derby, N.A. Switz, M. Armstrong, A.R. Harris, N. Prywes, M. Lukarska, S.B. Biering, D.C.J. Smock, A. Mok, G.J. Knott, Q. Dang, E. Van Dis, E. Dugan, S. Kim, T.Y. Liu<\/strong>, IGI Testing Consortium, E. Harris, S.A. Stanley, L.F. Lareau, M.X. Tan, D.A. Fletcher, J.A. Doudna, D.F. Savage, P.D. Hsu. medRxiv<\/em> [Preprint]. 2020.12.14.20247874<\/p>\n

2020<\/h5>\n

Chemistry of Class 1 CRISPR-Cas effectors: binding, editing, and regulation.<\/a> T.Y. Liu<\/b>, J.A. Doudna. J. Biol. Chem.<\/em> 295(42):14473-14487. PMID: 32817336<\/p>\n

2019<\/h5>\n

Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble.<\/a> T.Y. Liu*<\/b>, J-J. Liu*, A.J. Aditham, E. Nogales, J.A. Doudna. Nature Communications.<\/em> 10(1):3001. PMID: 31278272<\/p>\n

2017<\/h5>\n

RNA and DNA targeting by a reconstituted Thermus thermophilus Type III-A CRISPR-Cas system.<\/a> T.Y. Liu<\/b>, A.T. Iavarone, J.A. Doudna. PLoS One.<\/em> 12(1): e0170552. PMID: 28114398. Top 10% most cited articles of PLoS One in 2017.<\/em><\/strong><\/p>\n

Reconstitution of the tubular endoplasmic reticulum with purified components.<\/a> R.E. Powers*, S.Y. Wang*, T.Y. Liu<\/b>, T.A. Rapoport. Nature<\/em>. 543(7644):257-260. PMID: 28225760<\/p>\n

2015<\/h5>\n

Cis and trans interactions between atlastin molecules during membrane fusion.<\/a> T.Y. Liu<\/b>, X. Bian, F. Romano-Chernac, T. Shemesh, T.A. Rapoport, J. Hu. Proc. Natl. Acad. Sci. USA.<\/em> 112(15):E1851-60. PMID: 25825753<\/p>\n

2012<\/h5>\n

Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion.<\/a> T.Y. Liu*<\/b>, X. Bian*, S. Sun, X. Hu, R.W. Klemm, W.A. Prinz, T.A. Rapoport, J. Hu. Proc. Natl. Acad. Sci. U S A.<\/em> 109(32): E2146-2154. PMID: 22802620<\/p>\n

2011<\/h5>\n

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes.<\/a> X. Bian*, R.W. Klemm*, T.Y. Liu*<\/b>, M. Zhang, S. Sun, X. Sui, X. Liu, T.A. Rapoport, J. Hu. Proc. Natl. Acad. Sci. U.S.A.<\/em> 108(10): 3976-3981. PMID: 21368113<\/p>\n

2010<\/h5>\n

Designed proteins to modulate cellular networks.<\/a> A.L. Cortajarena*, T.Y. Liu*<\/b>, M. Hochstrasser, L. Regan. ACS Chemical Biology.<\/em> 5(6): 545-552. PMID: 20020775<\/p>\n

Screening Libraries to identify proteins with desired binding activities using a split-GFP reassembly assay.<\/a> M.E. Jackrel, A.L. Cortajarena, T.Y. Liu<\/b>, L. Regan. ACS Chemical Biology.<\/em> 5(6): 553-562. PMID: 20038141<\/p>\n

2009<\/h5>\n

Chapter 3. Lymphotactin structural dynamics.<\/a> B.F. Volkman, T.Y. Liu<\/b>, F.C. Peterson. Methods in Enzymology.<\/em> 461: 51-70. PMID: 19480914<\/p>\n","protected":false},"excerpt":{"rendered":"

2026 Programmable kinetic barcoding for multiplexed RNA detection with Cas13a.\u00a0S. Son, A. Lyden, C.F. Ng, A. Dextre, J.\u00a0Shu, S.I. Stephens, P. Fozouni, G.J. Knott, D.C.J. Smock, T.Y. Liu, D. Boehm, … Read More<\/a><\/p>\n","protected":false},"author":3032,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-custom.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nTina Liu Lab - Publications<\/title>\n<meta name=\"description\" content=\"Publications and preprints from Tina Liu's laboratory in the Center for Advanced Biotechnology & Medicine at Rutgers University.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/tina-liu-lab\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tina Liu Lab - Publications\" \/>\n<meta property=\"og:description\" content=\"Publications and preprints from Tina Liu's laboratory in the Center for Advanced Biotechnology & Medicine at Rutgers University.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/tina-liu-lab\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Tina Liu Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-01T22:43:41+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/tina-liu-lab\/publications\/\",\"url\":\"https:\/\/sites.rutgers.edu\/tina-liu-lab\/publications\/\",\"name\":\"Tina Liu Lab - 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