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CPM

Center for Protein Modification

 

Center for Protein Modification (CPM) provides the start-of-the-art proteomics technologies to support innovative projects and educate next-generation scientists, facilitating research discoveries around Post-translational Modifications (PTMs), chemical modifications (e.g., ABPP), and proteome dynamics in basic, translational, and clinical sciences. Launched in August 2026, CPM welcomes collaborations at two levels:

  1. Research collaboration: joint investment and brainstorming to solve a new scientific problem, discover a new modification, or contribute critical data to a future paper or grant specific aim. This is best for collaborations that require pushing scientific boundaries through the development of new proteomics methods, experimental design, or new software/code.
  2. Fee-for-Service: collaborator’s need-based service on data acquisition, sample preparation, or data analysis. Using well-established protocols and methods, this is best for collaborations with clear, specific proteomics needs. Rates are based on approved charges by the Rutgers Costing Group, per sample.

 

Example protocols

  • Whole proteome DDA (Data-dependent Acquisition).
  • Whole proteome DIA (Data-independent Acquisition).

DDA vs. DIA: The Essential Guide to Label-Free Quantitative Proteomics - MetwareBio

  • Protein interactome/immunoprecipitation mass spectrometry (IPMS)

  • Rapid immunoprecipitation mass spectrometry of endogenous proteins (RIME)

Rapid immunoprecipitation mass spectrometry of endogenous proteins (RIME) for analysis of chromatin complexes | Nature Protocols

  • ATE1-based Arginylation Profiling (ABAP)

  • Activity-based protein profiling (ABPP)

Activity-based protein profiling for mapping and pharmacologically interrogating proteome-wide ligandable hotspots - ScienceDirect

 

Partners

Biological Mass Spectrometry Facility (BMSF), Rutgers Busch Campus, https://cabm.rutgers.edu/research/mass-spectrometry-facility

Center for Advance Metabolomics and Proteomics Research (CAMPR), Rutgers NJMS Newark, https://research-office.njms.rutgers.edu/core-facilities/capr

Contact

CPM provides consultation, training, and advice to investigators and trainees willing to use proteomics for their research ideas and projects.

Director: Tom Lin, PhD

Shipping

Attn: Tom Lin
Center for Protein Modification
Ernest Mario School of Pharmacy
Rutgers University
William Levine Hall, Room 323
160 Frelinghuysen Road, Piscataway, NJ 08854
Tel: 848-445-3281. Email: tom.z.lin at rutgers.edu