{"id":363,"date":"2020-07-09T16:51:59","date_gmt":"2020-07-09T16:51:59","guid":{"rendered":"http:\/\/sites.rutgers.edu\/wei-xing-zong\/?page_id=363"},"modified":"2026-01-13T22:02:38","modified_gmt":"2026-01-13T22:02:38","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.rutgers.edu\/wei-xing-zong\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

2026<\/p>\n

Han X, Shen J, Yan J, Tacke R, Dai W, Mao Q, Daguplo HQ, Liu S, Islam A, Liu T, Koch MC, Lin RZ, Li H, Anthony T, Xie P, Zhang L, Gao S, Simon MC, Chen X, Yang J, Su X, and Zong WX*<\/strong>. Impaired nitrogenous waste clearance promotes hepatocellular carcinoma. Sci Adv.<\/em><\/strong> 2026. Jan 09. PMID: 41512056. DOI: 10.1126\/sciadv.aec0766<\/a>.<\/p>\n

 <\/p>\n

2025<\/p>\n

Meng X, Wang W, Sheshadri N, Zhang T, Han X, Sun Y, Xiao M, Feng Y, Gao S, Chen J, Xie S, Wang Y, Yang Y, Zhao Y, Yin Y, Zong WX*<\/strong> (co-corresponding author)<\/strong>, and Gao S*. SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3\u2019s activity and promotes lung tumorigenesis. Cell Death Dis.<\/em><\/strong> 2025 Dec 24. doi:10.1038\/s41419-025-08347-9<\/a><\/span><\/p>\n

Ma X, Wei X, Niu M, Zhang C, Peng Z, Liu W, Yan J, Su X, Ma L, Lu S, Cui W, Sesaki H, Zong WX<\/strong>, Ni HM, and Ding WX. Genetic disruption of mitochondrial dynamics and stasis leads to liver injury and tumorigenesis. J Clin Invest<\/strong><\/em>. 2025. Dec 16:e194441. https:\/\/doi.org\/10.1172\/JCI194441<\/a><\/p>\n

Jung J, Zhu S, Lalani A, Shakarchi J, Matracz B, Wu GG, Zong WX<\/strong>, Zhao L, Xie P. Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency. Blood Cancer Discov<\/em><\/strong>. 2025 Jul 3. PMID:\u00a040608826. doi: 10.1158\/2643-3230.BCD-24-0279<\/a>.<\/p>\n

Yan Y, Wang N, Xing B, Yang M, Shang J, Bao Y, Xiao L, Zhang N, Ren Y, Liu C, Chen Y, Han H, Pan Y, Lv L,\u00a0Zong WX<\/strong>, Ji H, Zhan C, Wang Z, Chen H, Wang Y. Splicing shift of RAC1 accelerates tumorigenesis and defines a potent therapeutic target in lung cancer. Adv Sci<\/em><\/strong>. 2025 Jun 23:e03322. PMID:\u00a040548642. doi: 10.1002\/advs.202503322<\/a>.<\/p>\n

Han HV, Efem R, Rosati B, Lu K, Maimouni S, Jiang YP, Montoya V, Van Der Velden A,\u00a0Zong WX<\/strong>, Lin RZ. Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model. eLife<\/em><\/strong>. 2025 Mar 11;13:RP96925. PMID:\u00a040067762. doi:10.7554\/eLife.96925.2<\/a>.<\/p>\n

Li P, Dong X, Xu L, Hu X, Meng X, Yang P, Zhang X,\u00a0Zong WX<\/strong>, Gao S, Zhuang S, Xin H.
\nTRIM21 knockout alleviates renal fibrosis by promoting autophagic degradation of mature TGF-\u03b21. Biochem Pharmacol<\/em><\/strong>. 2025 Apr; 234:116822. PMID:\u00a039983846. doi: 10.1016\/j.bcp.2025.116822<\/a>. Epub 2025 Feb 19.<\/p>\n

 <\/p>\n

2024<\/p>\n

Yang P#<\/sup>, Gao S#<\/sup> (co-first author), Shen J, Liu T, Lu K, Han X, Wang J, Ni HM, Ding WX, Li H, Pan JA, Peng K* (co-corresponding), and Zong WX*<\/strong>. TRIM21-mediated ubiquitylation of SQSTM1\/p62 abolishes its Ser403 phosphorylation and enhances palmitic acid cytotoxicity. Autophagy<\/em><\/strong>. 2024 September 10: 1-13. PMID: 39172027. DOI:\u00a010.1080\/15548627.2024.2394308<\/a>.<\/p>\n

Han X#<\/sup>, Wang D# <\/sup>(co-first author), Yang L, Wang N, Shen J, Wang J, Zhang L, Chen L, Gao S, Zong WX* (co-corresponding)<\/strong>, and Wang Y*. 2024. Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer. PNAS<\/em><\/strong>. 2024 Mar 26;121(13):e2319429121. PMID:\u00a038513095. doi: 10.1073\/pnas.2319429121<\/a>.<\/p>\n

Yang X, Wang J, Chang CY, Zhou F, Liu J, Xu H, Ibrahim M, Gomez M, Zong WX<\/strong>, Wondisford FE, Su X, White E, Feng Z, and Hu W. 2023. Leukemia inhibitory factor suppresses hepatic de novo<\/em> lipogenesis and induces cachexia. Nat Communi<\/em>. <\/strong>2024 Jan 20;15(1):627. PMID:\u00a038245529. doi: 10.1038\/s41467-024-44924-w<\/a>.<\/p>\n

Hou K, Liu L, Fang ZH, Zong WX<\/strong>, Sun D, Guo Z, and Cao L. The role of ferroptosis in cardio-oncology. Arch Toxicol<\/em><\/strong>. 2024 Jan 5. PMID: 38182913. doi: 10.1007\/s00204-023-03665-3<\/a>.<\/p>\n

 <\/p>\n

2023<\/p>\n

Xu N, Ren Y, Bao Y, Shen X, Kang J, Wang N, Wang Z, Han X, Li Z, Zuo J, Wei GH, Wang Z, Zong WX<\/strong>, Liu W, Xie G, and Wang Y. PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C. Cell Rep<\/em><\/strong>. 2023 Sep 7;42(9):113041. PMID:\u00a037682709. DOI:\u00a010.1016\/j.celrep.2023.113041<\/a>.<\/p>\n

Winz C, Zong WX<\/strong>, and Suh N. Endocrine-disrupting compounds and metabolomic reprogramming in breast cancer. J Biochem Mol Toxicol<\/em><\/strong>. 2023 Aug 20;e23506. PMID:\u00a037598318. DOI:\u00a010.1002\/jbt.23506<\/a>.<\/p>\n

Chao X, Wang S, Ma X, Zhang C, Qian H, Williams SN, Sun Z, Peng Z, Liu W, Li F, Sheshadri N, Zong WX, Ni HM, and Ding WX. Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis. Hepatology<\/em><\/strong>. 2023 Apr 3. PMID:\u00a036999531. doi: 10.1097\/HEP.0000000000000373<\/a>.<\/p>\n

Sun X, Huang N, Li P, Dong X, Yang J, Zhang X,\u00a0Zong WX, Gao S, Xin H. TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia\/reperfusion-induced acute kidney injury. Life Sci<\/em>.<\/strong> 2023 Mar 21;321:121608. PMID:\u00a036958437. doi: 10.1016\/j.lfs.2023.121608<\/a>.<\/p>\n

Bao Y, Zhang S, Zhang X, Pan Y, Yan Y, Wang N, Ren Y, Zuo J,\u00a0Zong WX<\/strong>, Wang Z, and Wang Y. RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition. Cancer Res<\/em><\/strong>. 2023 Feb 28:CAN-22-1549. PMID:\u00a036853175. doi: 10.1158\/0008-5472.CAN-22-1549<\/a>.<\/p>\n

Dai W and Zong WX*<\/strong>. Glutamine synthetase, a tumor suppressor in hepatocellular carcinoma? <\/em>J Mol Cell Biol.<\/em><\/strong> 2023 Feb 3:mjad007. PMID:\u00a036737414. PMID:\u00a036737414. DOI:\u00a010.1093\/jmcb\/mjad007<\/a>.<\/p>\n

Liu J, Zhang C, Xu D, Zhang T, Chang CY, Wang J, Liu J, Zhang L, Haffty BG,\u00a0Zong WX<\/strong>, Hu W, and Feng Z. The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain-of-function in cancer. J Clin Invest<\/em><\/strong>. 2023 Feb 7:e164354 (2023). PMID:\u00a036749630. DOI:\u00a010.1172\/JCI164354<\/a>.<\/p>\n

 <\/p>\n

2022<\/p>\n

Dai W#<\/sup>, Shen J# <\/sup>(co-first author), Yan J, Bott AJ, Maimouni S, Daguplo HQ, Wang Y, Khayati K, Guo JY, Zhang L, Wang Y, Gao S, Valvezan A, Ding WX, Chen X, Su X, and Zong WX*<\/sup><\/strong>. Glutamine synthetase limits b-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1. J Clin Invest<\/em><\/strong>. 2022 Oct 18:e161408. PMID: 36256480. DOI: 10.1172\/JCI161408<\/a>.<\/p>\n

Huang Y. Du S. Liu, Huang W,\u00a0Liu W,\u00a0Zhang M,\u00a0Li N,\u00a0Wang R,\u00a0Wu J,\u00a0Chen W,\u00a0Jiang M,\u00a0Zhou T,\u00a0Cao J,\u00a0Yang J,\u00a0Huang L,\u00a0Gu A,\u00a0Niu\u00a0J,\u00a0Cao Y,\u00a0Zong WX<\/strong>,\u00a0Wang\u00a0X, Liu\u00a0J, Qian K, and\u00a0Wang H. Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints. PNAS<\/em><\/strong> 119\u00a0(12)\u00a0e2122245119 (2022). PMID:\u00a035302894. DOI:\u00a010.1073\/pnas.2122245119<\/a>.<\/strong><\/p>\n

 <\/p>\n

2021<\/p>\n

Shen N, Korm S, Karantanos T, Li D, Zhang X, Ritou E, Xu H, Lam A, English J, Zong WX<\/strong>, Liu CT, Shirihai O, and Feng H. DLST-dependence dictates metabolic heterogeneity in TCA-cycle usage among triple-negative breast cancer. Communi Biol<\/em><\/strong>. 2021 Nov 16;4(1):1289. PMID:\u00a034785772. DOI:\u00a010.1038\/s42003-021-02805-8<\/a>.<\/p>\n

Liu Y, Gokhale S, Jung J, Zhu S, Luo C, Saha D, Guo JY, Zhang H, Kyin S,\u00a0Zong WX<\/strong>, White E, Xie P. Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes. Front Immunol<\/em><\/strong> 2021 Oct 20;12:670338. PMID:\u00a034745083. DOI:\u00a010.3389\/fimmu.2021.670338<\/a>.<\/p>\n

Chao X, Wang S, Fulte S, Ma X, Ahamed F, Cui W, Liu Z, R\u00fclicke T, Zatloukal K,\u00a0Zong WX<\/strong>, Liu W, Ni HM, Ding WX. Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy. J Hepatol<\/em><\/strong> 2021 Oct 25;S0168-8278(21)02151-6. PMID:\u00a034710483. DOI:\u00a010.1016\/j.jhep.2021.10.014<\/a>.<\/p>\n

Ouyang X, Becker E Jr, Bone NB, Johnson MS, Craver J,\u00a0Zong WX<\/strong>, Darley-Usmar VM, Zmijewski JW, and Zhang J. ZKSCAN3 in severe bacterial lung infection and sepsis-induced immunosuppression. Lab Invest<\/em><\/strong>. 2021. Sep 9. PMID:\u00a034504306. DOI:\u00a010.1038\/s41374-021-00660-z<\/a>.<\/p>\n

Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, and Zong WX*.<\/strong> Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. EBioMedicine<\/em><\/strong> 69:103456 (2021). PMID:\u00a034233258. DOI:\u00a010.1016\/j.ebiom.2021.103456<\/a>.<\/p>\n

Wang F#<\/sup>, Zhang Y# <\/sup>(co-first author), Shen J, Yang B, Dai W, Yan J, Maimouni S, Daguplo HQ, Coppola S, Gao Y, Wang Y, Du Z, Peng K, Liu H, Zhang Q, Tang F, Wang P, Gao S, Wang Y, Ding WX, Guo G, Wang F, and Zong WX*<\/sup><\/strong>. The ubiquitin E3 ligase TRIM21 promotes hepatocarcinogenesis by suppressing the p62-Keap1-Nrf2 antioxidant pathway. Cell Mol Gastroenterol Hepatol<\/em><\/strong>. 11(5):1369-1385 (2021). PMID:\u00a033482392. DOI:\u00a010.1016\/j.jcmgh.2021.01.007<\/a>.<\/p>\n

 <\/p>\n

2020<\/p>\n

Zhang S, Bao Y, Shen X, Pan Y, Sun Y, Xiao M, Chen K, Wei H, Zuo J, Saffen D,\u00a0Zong WX<\/strong>, Sun Y, Wang Z, and Wang Y. RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H. EBioMedicine<\/em><\/strong>. 2020 Nov;6. 1:103067. PMID:\u00a033130397. DOI:\u00a010.1016\/j.ebiom.2020.103067<\/a>.<\/p>\n

Tseng HC, Xiong W, Badeti S, Yang Y, Ma M, Liu T, Ramos CA, Dotti G, Fritzky L, Jiang JG, Yi Q, Guarrera J,\u00a0Zong WX<\/strong>, Liu C, and Liu D. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Communi<\/em><\/strong> 2020 Sep 23;11(1):4810. PMID:\u00a032968061. doi: 10.1038\/s41467-020-18444-2<\/a>.<\/p>\n

Su X, Chiles E, Maimouni S, Wondisford F, Zong WX<\/strong>, and Song C. In-source CID ramping (InCIDR) and covariant ion analysis of hydrophilic interaction chromatography (HILIC) metabolomics. Anal Chem<\/em><\/strong> 92:4829-4837. 2020 Apr 7. PMID:\u00a032125145. DOI:\u00a010.1021\/acs.analchem.9b04181<\/a>.<\/p>\n

Bhattacharya M, Dragan M, Nguyen MU, Guzman S, Goertzen C, Brackstone M, Dhillo W, Bech P, Clarke S, Abbara A, Tuck A, Hess D, Pine S, Zong WX<\/strong>, Wondisford F, Su X, and Babwah A. G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer. Cell Death Dis<\/em><\/strong>.11:106. (2020). PMID:\u00a032034133. DOI:\u00a010.1038\/s41419-020-2305-7<\/a>.<\/p>\n

 <\/p>\n

2019<\/p>\n

Bott AJ, Maimouni S, and Zong WX*<\/strong>. The pleiotropic effects of glutamine metabolism in cancer. Cancers<\/em><\/strong> 11: pii: E770 (2019). PMID:\u00a031167399. DOI:\u00a010.3390\/cancers11060770<\/a>.<\/p>\n

Dong Y, Hu Y, Sarkar S,\u00a0Zong WX<\/strong>, Li M, Feng D, Song JX, Li M, Medina DL, Tan J, Zhang Z, Yue Z, and Lu JH. Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies. Autophagy<\/em><\/strong> 2019 Dec 23:1-8. PMID:\u00a031841063. DOI:\u00a010.1080\/15548627.2019.1704119<\/a>.<\/p>\n

Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, Morton J, Anthony TG, Feng H, Lamers WH, Murphy D, Guo JY, Jin J, Crawford HC, Zhang L, White E, Lin RZ, Su X, Tuveson D, and Zong WX*<\/strong>. Glutamine anabolism plays a critical role in pancreatic cancer by coupling carbon and nitrogen metabolism. Cell Rep<\/em><\/strong> 29:1287-1298. (2019). PMID:\u00a031665640. DOI:\u00a010.1016\/j.celrep.2019.09.056<\/a>.<\/p>\n

Ni HM, Chao X, Yang H, Deng F, Wang S, Bai Q, Qian H, Cui Y, Cui W, Shi Y, Zong WX<\/strong>, Yang L, Wang Z, and Ding WX. Dual roles of mTOR in regulating liver injury and tumorigenesis in autophagy defective mouse liver. Hepatology<\/em><\/strong> 70:2142-2155. (2019). PMID:\u00a031095752. DOI:\u00a010.1002\/hep.30770<\/a>.<\/p>\n

Xu M, Almasi S, Yang Y, Yan C, Sterea AM, Rizvi Syeda AK, Shen B, Richard Derek C, Huang P, Gujar S, Wang J, Zong WX<\/strong>, Trebak M, El Hiani Y, and Dong XP. The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways. Cell Calcium<\/em><\/strong> 79:80-88. (2019). PMID:\u00a030889511. DOI:\u00a010.1016\/j.ceca.2019.02.010<\/a>.<\/p>\n

 <\/p>\n

2018<\/p>\n

Khambu B, Huda N, Chen X, Antoine DJ, Li Y, Dai G, K\u00f6hler UA, Zong WX<\/strong>, Waguri S, Werner S, Oury TD, Dong Z, and Yin XM. HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers. J Clin Invest<\/em><\/strong>.<\/strong> 128:2419-2435. (2018). PMID:\u00a029558368. DOI:\u00a010.1172\/JCI91814<\/a>.<\/p>\n

 <\/p>\n

2017<\/p>\n

Law F, Seo JH, Wang Z, DeLeon JL, Bolis Y, Brown A, Zong WX<\/strong>, Du G, and Rocheleau CE. The VPS34 PI3K negatively regulates RAB-5 during endosome maturation. J Cell Sci<\/em>.<\/strong> 130:2007-2017. (2017). PMID:\u00a028455411. DOI:\u00a010.1242\/jcs.194746<\/a>.<\/p>\n

Liu S, Jiang YP, Ballou LM, Zong WX<\/strong>, and Lin RZ. Activation of G\u03b1q in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy. J Cardiovasc Pharmacol<\/em><\/strong> 69:198-211. (2017). PMID:\u00a028376509. DOI:\u00a010.1097\/FJC.0000000000000461<\/a>.<\/p>\n

Li Y, Zong WX<\/strong>,\u00a0 and Ding WX. Recycling the danger via lipid droplet biogenesis after autophagy. Autophagy<\/em><\/strong> 2017 Sep 5:1-3. PMID:\u00a028873005. DOI:\u00a010.1080\/15548627.2017.1371394<\/a>.<\/p>\n

Sun Y, Sheshardri N, and Zong WX*<\/strong>, SERPINB3 and B4: from biochemistry to biology. Semi Cell Dev Biol.<\/em><\/strong>\u00a062:170-177. (2017). PMID:\u00a027637160. DOI:\u00a010.1016\/j.semcdb.2016.09.005<\/a>.<\/p>\n

 <\/p>\n

2016<\/p>\n

Jaber N, Mohd-Naim N, Wang Z, DeLeon JL, Kim S, Zhong H, Sheshadri N, Dou Z, Edinger AL, Du G, Braga VMM, and Zong WX*<\/strong>. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase activating protein Armus. J Cell Sci<\/em><\/strong> 129: 4424-4435. (2016). PMID:\u00a027793976. DOI:\u00a010.1242\/jcs.192260<\/a>.<\/p>\n

PanJA, SunY, JiangYP, BottAJ, JaberN, DouZ, YangB, ChenJS, CatanzaroJM, DuC, DingWX, Diaz-MecoMT,MoscatJ, OzatoK, LinRZ, and Zong WX*<\/strong>. TRIM21 ubiquitylates SQSTM1\/p62 and suppresses protein sequestration to regulate redox homeostasis. Mol Cell<\/em><\/strong> 61: 720-733. \u201cFeatured Article\u201d. (2016). PMID:\u00a026942676. DOI:\u00a010.1016\/j.molcel.2016.02.007<\/a>.<\/p>\n

Zong WX<\/strong>, Rabinowitz JD, and White E. Mitochondria and cancer. Mol Cell<\/em> <\/strong>61: 667-676. (2016). PMID: 26942671. DOI: 10.1016\/j.molcel.2016.02.011<\/a>.<\/p>\n

Klionsky D, et al., Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd<\/sup> edition). Autophagy<\/em><\/strong> 12:1-222. (2016). PMID:\u00a026799652. DOI:\u00a010.1080\/15548627.2015.1100356<\/a>.<\/p>\n

 <\/p>\n

2015<\/p>\n

Bott AJ#<\/sup>, Peng IC#<\/sup> (co-first author),\u00a0Fan Y, Faubert B, Zhao L, Li J, Neidler S, Sun Y, Jaber N, Krokowski D, Lu W, Pan JA, Powers S, Rabinowitz J, Hatzoglou M, Murphy DJ, Jones R, Wu S, Girnun G, and Zong WX*<\/strong>. \u00a0<\/sup>Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation. Cell Metab<\/em><\/strong> 22:1068-1077. (2015). PMID:\u00a026603296. DOI:\u00a010.1016\/j.cmet.2015.09.025<\/a>.<\/p>\n

Dou Z, Xu C , Donahue G, Shimi T, Pan JA, Zhu J, Ivanov A, Capell B, Drake A, Shah P, Catanzaro J, Ricketts M, Lamark T, Adam S, Marmorstein R, Zong WX<\/strong>, Johansen T, Goldman R, Adams P, and Berger S. Autophagy mediates degradation of nuclear lamina. Nature<\/em><\/strong> 527:105-109. (2015). PMID:\u00a026524528. DOI:\u00a010.1038\/nature15548<\/a>.<\/p>\n

Naguib A, Bencze G, Cho H, Zheng W, Tocilj A, Elkayam E, Faehnle CR, Jaber N, Pratt CP, Chen M, Zong WX<\/strong>, Marks MS, Joshua-Tor L, Pappin DJ, and Trotman LC. PTEN function by recruitment to cytoplasmic vesicles. Mol Cell<\/em><\/strong> 16:255-268. (2015). PMID:\u00a025866245. DOI:\u00a010.1016\/j.molcel.2015.03.011<\/a>.<\/p>\n

 <\/p>\n

2014<\/p>\n

Sheshadri N#<\/sup>, Catanzaro JM# <\/sup>(co-first author), Bott A, Sun Y, Ullman E, Wu S, Pan JA, Chen E, Crawford HC, Zhang J, and Zong WX*<\/strong>. SCCA1\/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling. Cancer Res<\/em><\/strong> 74:6318-6329. (2014). PMID:\u00a025213322. DOI:\u00a010.1158\/0008-5472.CAN-14-0798<\/a>.<\/p>\n

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX<\/strong>, and Yue Z. Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex. PLoS Genetics<\/em><\/strong> 10:e1004626. (2014). PMID:\u00a025275521. DOI:\u00a010.1371\/journal.pgen.1004626<\/a>.<\/p>\n

Lu J, He L, Behrends C, Araki M, Araki K, Wang QJ, Catanzaro JM, Friedman SL, Zong WX<\/strong>, Fiel MI, Li M, and Yue Z. NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun<\/em><\/strong> 5:3920. (2014). PMID:\u00a024849286. DOI:\u00a010.1038\/ncomms4920<\/a>.<\/p>\n

Catanzaro JM#<\/sup>, Sheshadri N#<\/sup> (co-first author), Pan JA, Sun Y, Shi C, Li J, Powers RS, Crawford HC, and Zong WX*<\/strong>. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3\/B4. Nat Commun<\/em><\/strong> 5: 3729. (2014). PMID:\u00a024759783. DOI:\u00a010.1038\/ncomms4729<\/a>.<\/p>\n

Doyle CP, Pan JA, Mena P, Zong WX<\/strong>, and Thanassi DG. TolC-Dependent Modulation of Host Cell Death by the Francisella tularensis <\/em>Live Vaccine Strain. Infect Immunol<\/em><\/strong> 82:2068-2078. (2014). PMID:\u00a024614652. DOI:\u00a010.1128\/IAI.00044-14<\/a>.<\/p>\n

Catanzaro JM, Sheshadri N, and Zong WX*<\/strong>. SerpinB3\/B4: mediators of Ras-driven inflammation and oncogenesis. Cell Cycle<\/em><\/strong> 13:3155-3156. (2014). PMID:\u00a025485489. DOI:\u00a010.4161\/15384101.2014.969991<\/a>.<\/p>\n

Kepp O et al. Consensus guidelines for the detection of immunogenic cell death. Oncoimmunology<\/em><\/strong> in press. (2014). PMID:\u00a025941621. DOI:\u00a010.4161\/21624011.2014.955691<\/a>.<\/p>\n

 <\/p>\n

2013<\/p>\n

Parekh VV, Wu L, Boyd KL, Williams JA, Gaddy JA, Olivares-Villag\u00f3mez D, Cover TL, Zong WX,<\/strong> Zhang J, and Van Kaer L. Impaired autophagy, defective T cell homeostasis and a wasting syndrome in mice with a T cell-specific deletion of Vps34. J Immunol<\/em><\/strong> 190:5086-5101. (2013). PMID:\u00a023596309. DOI:\u00a010.4049\/jimmunol.1202071<\/a>.<\/p>\n

Dou Z, Pan JA, Dbouk HA, Ballou LM, DeLeon JL, Fan YJ, Chen JS, Liang Z, Li G, Backer JM, Lin RZ, and Zong WX*<\/strong>. Class IA PI3 p110\u03b2 subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation. Mol Cell<\/em><\/strong> 50:29-42. (2013). PMID:\u00a023434372. DOI:\u00a010.1016\/j.molcel.2013.01.022<\/a>.<\/p>\n

Fan Y and Zong WX*<\/strong>. The cellular decision between apoptosis and autophagy. Chin J Cancer<\/em><\/strong> 32:121-129. (2013). PMID:\u00a023114086. DOI:\u00a010.5732\/cjc.012.10106<\/a>.<\/p>\n

Pan JA. Fan Y. Gandhirajan RK, Madesh M. and Zong WX*<\/strong>. Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis. J Biol Chem<\/em><\/strong> 288:2952-2963. (2013) (editorially selected as \u201cPaper-of-the-week\u201d). PMID:\u00a023239879. DOI:\u00a010.1074\/jbc.M112.441063<\/a>.<\/p>\n

 <\/p>\n

2012<\/p>\n

Klionsky D, et al., Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy in Higher Eukaryotes. Autophagy<\/em><\/strong>.8:445-544. (2012). PMID:\u00a022966490. DOI:\u00a010.4161\/auto.19496<\/a>.<\/p>\n

Jaber N, Dou Z, Lin RZ, Zhang J, and Zong WX*<\/strong>. Mammalian PIK3C3\/VPS34: the key to autophagic processing in liver and heart. Autophagy <\/em><\/strong>8: 707-708. (2012). PMID:\u00a022498475. DOI:\u00a010.4161\/auto.19627<\/a>.<\/p>\n

Guerriero JL, Ditsworth D, and Zong WX*<\/strong>. Non-apoptotic routes to defeat cancer. Oncoimmunol<\/em><\/strong>\u00a01:94-96. (2012). PMID:\u00a022720222. DOI:\u00a010.4161\/onci.1.1.17885<\/a>.<\/p>\n

Jaber N, Dou Z, Chen JS, Catanzaro J, Jiang YP, Ballou LM, Selinger E, Ouyang X, Lin RZ, Zhang J* (co-corresponding author), and Zong WX*<\/strong>. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. PNAS <\/em><\/strong>109:2003-2008. (2012). PMID:\u00a022308354. DOI:\u00a010.1073\/pnas.1112848109<\/a>.<\/p>\n

 <\/p>\n

2011<\/p>\n

Dou Z, Pan JA, Lin RZ, and Zong WX*<\/strong>. The beta identity of class I PtdIns3K: A positive role of p110\u03b2 in autophagy revealed. Autophagy<\/em><\/strong>. 7:246-247. (2011). PMID:\u00a021160279. DOI:\u00a010.4161\/auto.7.2.14346<\/a>.<\/p>\n

Pan JA, Ullman E, Dou Z, and Zong WX*<\/strong>. Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes. Mol Cell Biol<\/em> <\/strong>31:3158-3170. (2011). PMID:\u00a021628531. DOI:\u00a010.1128\/MCB.05460-11<\/a>.<\/p>\n

Ullman E, Pan JA, and Zong WX*<\/strong>. Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury. Mol Cell Biol<\/em> <\/strong>31:2902-2919. (2011). PMID:\u00a021576355. DOI:\u00a010.1128\/MCB.05452-11<\/a>.<\/p>\n

Catanzaro JM#<\/sup>, Guerriero JL# <\/sup>(co-first author), Liu J, Ullman E, Sheshadri N, Chen JJ, and Zong WX*<\/strong>. Elevated expression of squamous cell carcinoma antigen (SCCA) is associated with human breast carcinoma.\u00a0 PLoS One<\/em><\/strong> 6: e19096. (2011). PMID:\u00a021526154. DOI:\u00a010.1371\/journal.pone.0019096<\/a>.<\/p>\n

Guerriero JL, Ditsworth D, Catanzaro JM, Sabino G, Furie MB, Kew R, and Zong WX*<\/strong>. DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol<\/em><\/strong> 186:3517-3626. (2011) (editorially selected as a \u201cFeatured Article\u201d). PMID:\u00a021300822. DOI:\u00a010.4049\/jimmunol.1003267<\/a>.<\/p>\n

Lin F, Ren XD, Pan Z, Macri L, Zong WX<\/strong>, Tonnesen MG, Rafailovich M, Bar-Sagi D, and Clark RA. Fibronectin growth factor-binding domains are required for fibroblast survival. J Invest Dermatol<\/em><\/strong> 131(1):84-98. (2011). PMID:\u00a020811396. DOI:\u00a010.1038\/jid.2010.253<\/a>.<\/p>\n

 <\/p>\n

2010<\/p>\n

Catanzaro J and Zong WX*<\/strong>.\u00a0 Pinpointing Pin1 in non-small cell lung carcinoma. Cancer Biol Ther<\/em><\/strong> 9:120-121. (2010). PMID:\u00a020023388. DOI:\u00a010.4161\/cbt.9.2.10767<\/a>.<\/p>\n

Dou Z, Chattopadhyay M, Pan JA, Guerriero JL, Jiang YP, Ballou LM, Yue Z, Lin RZ, and Zong WX*<\/strong>. The Class IA phosphatidylinositol 3-kinase p110\u03b2 subunit is a positive regulator of autophagy. J Cell Biol<\/em><\/strong> 191:827-843. (2010). PMID:\u00a021059846. DOI:\u00a010.1083\/jcb.201006056<\/a>.<\/p>\n

Fan Y, Dickman K, and Zong WX*<\/strong>. Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition. J Biol Chem<\/em><\/strong> 285: 7324-7333. (2010). PMID:\u00a020018866. DOI:\u00a010.1074\/jbc.M109.035584<\/a>.<\/p>\n

 <\/p>\n

2009<\/p>\n

Gruber J, Yong J, Zatechka DS, Sabin L, Zhang Z, Lum JJ, Kong M, Zong WX<\/strong>, Lau CK, Cherry S, Ihle J, Dreyfuss G, and Thompson CB. Ars2 links the nuclear cap binding complex to RNA interference and cell proliferation. Cell<\/em><\/strong> 138: 328-339. (2009). PMID:\u00a019632182. DOI:\u00a010.1016\/j.cell.2009.04.046<\/a>.<\/p>\n

Madesh M#<\/sup>, Zong WX#<\/sup> (co-first author)<\/strong>, Hawkins BJ, Ramasamy S, Venkatachalam T, Mukhopadhyay P, Doonan PJ, Irrinki KM, Rajesh M, Pacher P, and Thompson CB. Execution of superoxide-induced cell death by the proapoptotic Bcl-2-related proteins Bid and Bak. Mol Cell Biol<\/em><\/strong> 29:3099-3112. (2009). PMID:\u00a019332555. DOI:\u00a010.1128\/MCB.01845-08<\/a>.<\/p>\n

 <\/p>\n

2008<\/p>\n

Guerriero JL, Ditsworth D, Fan Y, Zhao F, Crawford HC, and Zong WX*<\/strong>. Chemotherapy induces tumor clearance independent of apoptosis. Cancer Res<\/em><\/strong> 68: 9595-9600. (2008). PMID:\u00a019047135. DOI:\u00a010.1158\/0008-5472.CAN-08-2452<\/a>.<\/p>\n

Singer AJ, McClain SA, Taira BR, Guerriero JL, and Zong WX<\/strong>. Apoptosis and necrosis in the ischemic zone adjacent to third degree burns. Acad Emerg Med<\/em><\/strong> 15: 549-54. (2008). PMID:\u00a018616442. DOI:\u00a010.1111\/j.1553-2712.2008.00115.x<\/a>.<\/p>\n

Fan Y and Zong WX*<\/strong>.\u00a0 Hacking hexokinase halts tumor growth. Cancer Biol Ther<\/em><\/strong> 7:1136-1138. (2008). PMID:\u00a018698161. DOI:\u00a010.4161\/cbt.7.7.6536<\/a>.<\/p>\n

Ullman E#<\/sup>, Fan Y#<\/sup> (co-first author), Stawowczyk M, Chen HM, Yue Z, and Zong WX*<\/strong>.\u00a0 Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress. Cell Death Diff<\/em><\/strong> 16:422-425. (2008). PMID:\u00a017917679. DOI:\u00a010.1038\/sj.cdd.4402234<\/a>.<\/p>\n

Simmons MJ, Fan G, Zong WX<\/strong>, Degenhardt K, White E, and G\u00e9linas C. Bfl-1\/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. Oncogene<\/em> <\/strong>27:1421-1428. (2008). PMID:\u00a017724464. DOI:\u00a010.1038\/sj.onc.1210771<\/a>.<\/p>\n

 <\/p>\n

2007<\/p>\n

Ditsworth D, Zong WX<\/strong>, and Thompson CB. Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. J Biol Chem<\/em><\/strong> 282:17845-17854. (2007). PMID:\u00a017430886. DOI:\u00a010.1074\/jbc.M701465200<\/a>.<\/p>\n

Banga S, Gao P, Shen X, Fiscus V, Zong WX<\/strong>, Chen L, and Luo ZQ. Legionella pneumophila <\/em>inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. PNAS<\/em><\/strong>. 104:5121-5126. (2007). PMID:\u00a017360363. DOI:\u00a010.1073\/pnas.0611030104<\/a>.<\/p>\n

 <\/p>\n

2006<\/p>\n

Ricci MS and Zong WX*<\/strong>.\u00a0 Chemotherapeutic approaches for targeting cell death pathways. The Oncologist<\/em><\/strong> 11: 342-357. (2006). PMID:\u00a016614230. DOI:\u00a010.1634\/theoncologist.11-4-342<\/a>.<\/p>\n

Zong WX<\/strong> and Thompson CB. 2006. Necrotic death as a cell fate. Genes Dev<\/em><\/strong> 20:1-15. PMID:\u00a016391229. DOI:\u00a010.1101\/gad.1376506<\/a>.<\/p>\n

Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong WX<\/strong>, Liao X, Maryam M, Hao X and Chen Q. Gossypol induces Bax\/Bak-independent activation of apoptosis and cytochrome C release via a conformational change in Bcl-2. FASEB J<\/em><\/strong> 20: 2147-2149. (2006). PMID:\u00a016935937. DOI:\u00a010.1096\/fj.05-5665fje<\/a>.<\/p>\n

Muthumani K, Choo AY, Zong WX<\/strong>, Hwang DS, Premkumar A, Thieu PT, Muniswamy M, Thompson CB, and Weiner DB. The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1. Nat Cell Biol<\/em><\/strong> 8:170-179. (2006). PMID:\u00a016429131. DOI:\u00a010.1038\/ncb1352<\/a>.<\/p>\n

 <\/p>\n

2005<\/p>\n

Thompson CB, Bauer DE, Lum JJ, Hatzivassiliou G, Zong WX<\/strong>, Zhao F, Ditsworth D, Buzzai M, Lindsten T. How do cancer cells acquire the fuel needed to support cell growth? Cold Spring Harb Symp Quant Biol<\/em><\/strong>. 70<\/strong>:357-62. (2005). PMID:\u00a016869772. DOI:\u00a010.1101\/sqb.2005.70.011<\/a>.<\/p>\n

Lindsten T, Zong WX<\/strong>, and Thompson CB. Defining the role of the Bcl-2 family of proteins in the nervous system. The Neuroscientist<\/em><\/strong> 11:10-15. (2005). PMID:\u00a015632274. DOI:\u00a010.1177\/1073858404269267<\/a>.<\/p>\n

 <\/p>\n

2004<\/p>\n

Ditsworth D and Zong WX*<\/strong>.\u00a0 NF-kappaB: Key mediator of inflammation-associated cancer. Cancer Biol Ther<\/em><\/strong> 3: 1214-1216. (2004). PMID:\u00a015611628. DOI:\u00a010.4161\/cbt.3.12.1391<\/a>.<\/p>\n

Zong WX*<\/strong>. Histone H1.2: Another Housekeeping Protein that Kills. Cancer Biol Ther<\/em><\/strong> 3, 42-43. (2004). PMID:\u00a014726680. DOI:\u00a010.4161\/cbt.3.1.738<\/a>.<\/p>\n

Zong WX<\/strong>, Ditsworth D, Bauer DE, Wang ZQ, and Thompson CB. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev<\/em><\/strong> 18: 1272-1282. (2004). PMID:\u00a015145826. DOI:\u00a010.1101\/gad.1199904<\/a>.<\/p>\n

Brunelle JK, Santore MT, Budinger GR, Tang Y, Barrett TA, Zong WX<\/strong>, Kandel E, Keith B, Simon MC, Thompson CB, Hay N, and Chandel NS. c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax\/Bak, but is independent of p53 and hypoxia-inducible factor-1. J Biol Chem<\/em><\/strong> 279, 4305-4312. (2004). PMID:\u00a014627695. DOI:\u00a010.1074\/jbc.M312241200<\/a>.<\/p>\n

Schnepp RW, Mao H, Sykes SM, Zong WX<\/strong>, Silva A, La P, and Hua X. Menin induces apoptosis in murine embryonic fibroblasts. J Biol Chem<\/em><\/strong> 279, 10685-10691. (2004). PMID:\u00a014688275. DOI:\u00a010.1074\/jbc.M308073200<\/a>.<\/p>\n

Melino G, Bernassola F, Ranalli M, Yee K, Zong WX<\/strong>, Corazzari M, Knight RA, Green DR, Thompson CB, and Vousden KH. p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J Biol Chem<\/em><\/strong> 279, 8076-8083. (2004). PMID:\u00a014634023. DOI:\u00a010.1074\/jbc.M307469200<\/a>.<\/p>\n

 <\/p>\n

2003<\/p>\n

Lindsten T, Golden JA, Zong WX<\/strong>, Minarcik J, Harris MH, and Thompson CB. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. J Neurosci<\/em> <\/strong>23, 11112-11119. (2003). PMID:\u00a014657169. DOI:\u00a010.1523\/JNEUROSCI.23-35-11112.2003<\/a>.<\/p>\n

Johnson TR, Stone K, Nikrad M, Yeh T, Zong WX<\/strong>, Thompson CB, Nesterov A, and Kraft AS. The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells. Oncogene<\/em><\/strong> 22, 4953-4963. (2003). PMID:\u00a012902978. DOI:\u00a010.1038\/sj.onc.1206656<\/a>.<\/p>\n

Zong WX#<\/sup><\/strong>, Li C# <\/sup>(co-first author), Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, and Thompson CB.\u00a0 Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis. J Cell Biol<\/em><\/strong> 162, 59-69. (2003). PMID:\u00a012847083. DOI:\u00a010.1083\/jcb.200302084<\/a>.<\/p>\n

 <\/p>\n

2002<\/p>\n

Rathmell JC, Lindsten T, Zong WX<\/strong>, Cinalli RM, and Thompson CB. Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis. Nat Immunol<\/em><\/strong> 3, 932-939. (2002). PMID:\u00a012244308. DOI:\u00a010.1038\/ni834<\/a>.<\/p>\n

Suh J, Payvandi F, Edelstein LC, Amenta PS, Zong WX<\/strong>, Gelinas C, and Rabson AB. Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells. Prostate<\/em><\/strong> 52, 183-200. (2002). PMID:\u00a012111695. DOI:\u00a010.1002\/pros.10082<\/a>.<\/p>\n

Lei K, Nimnual A, Zong WX<\/strong>, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, and Davis RJ. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol<\/em><\/strong> 22, 4929-4942. (2002). PMID:\u00a012052897. DOI:\u00a010.1128\/MCB.22.13.4929-4942.2002<\/a>.<\/p>\n

McClintock DS, Santore MT, Lee VY, Brunelle J, Budinger GR, Zong WX<\/strong>, Thompson CB, Hay N, and Chandel NS. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Mol Cell Biol<\/em> <\/strong>22, 94-104. (2002). PMID:\u00a011739725. DOI:\u00a010.1128\/MCB.22.1.94-104.2002<\/a>.<\/p>\n

 <\/p>\n

2001<\/p>\n

Zong WX<\/strong>, Lindsten T, Ross AJ, MacGregor GR, and Thompson CB. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev<\/em><\/strong> 15, 1481-1486. (2001). PMID:\u00a011410528. DOI:\u00a010.1101\/gad.897601<\/a>.<\/p>\n

Wei MC#<\/sup>, Zong WX#<\/sup> (co-first author)<\/strong>, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, and Korsmeyer SJ.\u00a0 Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science<\/em><\/strong> 292, 727-730. (2001). PMID:\u00a011326099. DOI:\u00a010.1126\/science.1059108<\/a>.<\/p>\n

 <\/p>\n

2000<\/p>\n

Lindsten T, Ross AJ, King A, Zong WX<\/strong>, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, and Thompson CB. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell<\/em><\/strong> 6, 1389-1399. (2000). PMID:\u00a011163212. DOI:\u00a010.1016\/s1097-2765(00)00136-2<\/a>.<\/p>\n

Luque I, Zong WX,<\/strong> Chen C, and Gelinas C. N-terminal determinants of I kappa B alpha necessary for the cytoplasmic regulation of c-Rel. Oncogene<\/em><\/strong> 19, 1239-1244. (2000). PMID:\u00a010713713. DOI:\u00a010.1038\/sj.onc.1203400<\/a>.<\/p>\n

 <\/p>\n

1999<\/p>\n

Bash J, Zong WX<\/strong>, Banga S, Rivera A, Ballard DW, Ron Y, and Gelinas C. Rel\/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors. EMBO J<\/em><\/strong> 18, 2803-2811. (1999). PMID:\u00a010329626. DOI:\u00a010.1093\/emboj\/18.10.2803<\/a>.<\/p>\n

Zong WX<\/strong>, Edelstein LC, Chen C, Bash J, and Gelinas C. The prosurvival Bcl-2 homolog Bfl-1\/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev<\/em><\/strong> 13, 382-387. (1999). PMID:\u00a010049353. DOI:\u00a010.1101\/gad.13.4.382<\/a><\/p>\n

 <\/p>\n

1998<\/p>\n

Zong WX<\/strong>, Bash J, and Gelinas C. Rel blocks both anti-Fas- and TNF alpha-induced apoptosis and an intact Rel transactivation domain is essential for this effect. Cell Death Diff<\/em><\/strong> 5, 963-972. (1998). PMID:\u00a09846183. DOI:\u00a010.1038\/sj.cdd.4400441<\/a><\/p>\n

 <\/p>\n

1997<\/p>\n

Bash J, Zong WX<\/strong>, and Gelinas C. c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1\/S-phase transition. Mol Cell Biol<\/em><\/strong> 17, 6526-6536. (1997). PMID:\u00a09343416.\u00a0DOI:\u00a010.1128\/MCB.17.11.6526<\/a><\/p>\n

Zong WX<\/strong>, Farrell M, Bash J, and Gelinas C. v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death. Oncogene<\/em><\/strong> 15, 971-980. (1997). PMID:\u00a09285692. DOI:\u00a010.1038\/sj.onc.1201266<\/a><\/p>\n

 <\/p>\n

1995<\/p>\n

Yeh CH, Zong WX<\/strong>, and Shatkin, AJ. The Ser36-Ser37 pair in HeLa nuclear protein p21\/SIIR mediates Ser\/Thr phosphorylation and is essential for Rous sarcoma virus long terminal repeat repression. J Biol Chem<\/em><\/strong> 270, 25313-25315. (1995). PMID:\u00a07592688. DOI:\u00a010.1074\/jbc.270.43.25313<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

2026 Han X, Shen J, Yan J, Tacke R, Dai W, Mao Q, Daguplo HQ, Liu S, Islam A, Liu T, Koch MC, Lin RZ, Li H, Anthony T, Xie … Read More<\/a><\/p>\n","protected":false},"author":21,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublications - Wei-Xing Zong Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.rutgers.edu\/wei-xing-zong\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Wei-Xing Zong Laboratory\" \/>\n<meta property=\"og:description\" content=\"2026 Han X, Shen J, Yan J, Tacke R, Dai W, Mao Q, Daguplo HQ, Liu S, Islam A, Liu T, Koch MC, Lin RZ, Li H, Anthony T, Xie … Read More\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sites.rutgers.edu\/wei-xing-zong\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Wei-Xing Zong Laboratory\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-13T22:02:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"20 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/sites.rutgers.edu\/wei-xing-zong\/publications\/\",\"url\":\"https:\/\/sites.rutgers.edu\/wei-xing-zong\/publications\/\",\"name\":\"Publications - 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