Microemulsions

Microemulsions are liquid nanodispersions composed of polar and non-polar phases stabilized with surfactant and usually a co-surfactant.  Because of their advantageous properties, they are frequently investigated as potential carriers useful in topical and transdermal drug delivery.  According to numerous scientific reports, microemulsions reveal good solubilizing properties, which is particularly important in formulations containing poorly soluble drugs. Moreover, microemulsion can enhance the permeation process, improving the bioavailability of the incorporated drug.  In our lab we investigate microemulsions and microemulsion-based polymer gels as potential carriers for topical and transdermal delivery of non-steroidal anti-inflammatory drugs. One of the most important aims of our studies is to assess the physicochemical factors which are crucial for the skin permeation and determine the therapeutic efficiency of the formulation.