Publications
2024
› Kochmanski J, Virani M, Kuhn NC, Boyd SL, Becker K, Adams M, and Bernstein AI. (2024) Developmental origins of Parkinson’s disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex specific DNA modifications in critical neurodevelopmental pathways in the mouse midbrain. Toxicological Sciences, kfae091, doi: 10.1093/toxsci/kfae091. 🔗
› John T. Gionco, and Alison I. Bernstein. (2024) Emerging Role of Environmental Epitranscriptomics and RNA modifications in Parkinson’s disease. Journal of Parkinson’s disease. (In Press) doi:10.3233/JPD-230457. 🔗
› Kochmanski and A.I. Bernstein (2024) Best practices for epigenome-wide DNA modifications data collection and analysis. In: Translational and Applied Genomics, Rigor and Reproducibility in Genetics and Genomics. D. Dluzen and M. Schmidt, ed. Academic Press. pp. 261-294. doi:10.1016/B978-0-12-817218-6.00006-1. 🔗
2023
› Sierra L. Boyd, Nathan C. Kuhn, Joseph R. Patterson, Anna C. Stoll, Sydney A. Zimmerman, Mason R. Kolanowski, Joseph J. Neubecker, Kelvin C. Luk, Eric S. Ramsson, Caryl E. Sortwell, and Alison I. Bernstein (2023) Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α- synuclein pre-formed fibril (PFF)-injected mice. Toxicological Sciences, kfad086, doi:10.1093/toxsci/kfad086. 🔗
- Preregistration DOI: 10.17605/OSF.IO/QV4YA
- Dataset DOI: 10.5061/dryad.qz612jmmq
2022
› Kochmanski J, Kuhn NA, and Bernstein AI. (2022) Parkinson’s Disease-Associated, Sex-specific Changes in DNA Methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in Cortical Neurons. Nature Partner Journals: Parkinson’s disease. 8 (120) doi:10.1038/s41531-022-00355-2. 🔗
- Preregistration DOI: 10.17605/osf.io/z4vbw
- Dataset DOI: 10.5061/dryad.7d7wm37w0
2020
› Gezer AO, Kochmanski J, VanOeveren SE, Cole-Strauss A, Kemp CJ, Patterson JR, Miller KM, Kuhn NC, Herman DE, McIntire A, Lipton JW, Luk KC, Fleming SM, Sortwell CE, Bernstein AI. (2020) Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits. Neurobiology of Disease.141:104947. doi: 10.1016/j.nbd.2020.104947. 🔗
- Preregistration DOI: 10.17605/osf.io/h49xf, 10.17605/osf.io/wpf6u
- Dataset DOI: 10.17632/h2ptyjr2cf.1
› Kochmanski, J. and Bernstein, A.I. (2020) The Impact of Environmental Health Factors on
5-Hydroxymethylcytosine in the Brain. Current Environmental Health Reports.
doi: 10.1007/s40572-020-00268-3. 🔗
2019
› Kochmanski J, Savonen C, Bernstein AI (2019) A Novel Application of Mixed Effects Models for
Reconciling Base-Pair Resolution 5-methylcytosine and 5-hydroxymethylcytosine Data in
Neuroepigenetics. Frontiers in Genetics. doi: 10.3389/fgene.2019.00801. 🔗
› Kochmanski J, VanOeveren SE, Patterson JR, Bernstein AI (2019) Developmental Dieldrin
Exposure Alters DNA Methylation at Genes Related to Dopaminergic Neuron Development
and Parkinson’s Disease in Mouse Midbrain. Toxicological Sciences. 169(2): 593-607.
doi:10.1093/toxsci/kfz069. 🔗
- Dataset DOI: 10.5061/dryad.s3n76mr
View Alison Bernstein’s NCBI Bibliography
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