8:30 – 9:00 AM.       Welcome and Introduction to the NIH Transporter Elucidation Network

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9:00 – 10:45 AM.     Advancing Translation in Perinatal Transporter Science

• Maternal Metabolomics throughout Pregnancy

• Defining the Placenta Transporter Proteome in Health and Disease

• Insights on Transporters from Human Milk

 x

11:00 – 12:00 PM.    ‘Omics Approaches to Study Perinatal Transporters

• Placental Transcriptomics and Proteomics

• Ontogeny of Human Intestinal Transporters

x 

12:00 –  1:00 PM.     Computational and Structural Biology Approaches to Transporter Science

• Structures of Blood Brain Barrier Transporters

• Advanced Machine Learning Models for Transport and Placental Transfer

 x

2:00 –  3:30 PM.       New Approach Methodologies (NAMs) for Perinatal Science

• Vectorial Transport in Human Intestinal Enteroids

• Organoids for Investigating Brain Transporters and MDCK Cysts for Polarized Localization

• Human Placenta-on-a-Chip to Study Maternal-Fetal Transfer and Health

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3:30 –  4:15 PM.      Panel Discussion

• What’s Next?  Challenges and Charting New Directions in Perinatal Transporter Science

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Posters from trainees and early career scientists will be available online for viewing during the lunch break.