8:30 – 9:00 AM.       Welcome and Introduction to the NIH Transporter Elucidation Network

x

9:00 – 10:30 AM.     Advancing Translation in Perinatal Transporter Science

• Predicting Gestational Ontogeny of Maternal-Fetal Drug Exposure: A Path Forward

• Defining the Placenta Transporter Proteome in Health and Disease

• Transporters from Mammary Organoids and Human Milk

 x

10:45 – 12:00 PM.    ‘Omics Approaches to Study Perinatal Transporters

• Placental Transcriptomics and Proteomics

• Ontogeny of Human Intestinal Transporters

x 

12:00 –  1:00 PM.     Computational and Structural Biology Approaches to Transporter Science

• Structures of Blood Brain Barrier Transporters

• Advanced Machine Learning Models for Transport and Placental Transfer

 x

1:00 –  2:00 PM.       Poster Session

• A select number of posters have been recorded for online attendees.  View recorded posters here. 

2:00 –  3:30 PM.       New Approach Methodologies (NAMs) for Perinatal Science

• Vectorial Transport in Human Intestinal Enteroids

• Organoids for Investigating Brain Transporters and MDCK Cysts for Polarized Localization – Recorded Video

• Human Placenta-on-a-Chip to Study Maternal-Fetal Transfer and Health

x 

3:30 –  4:30 PM.      Panel Discussion

• What’s Next?  Challenges and Charting New Directions in Perinatal Transporter Science

x

Posters from trainees and early career scientists will be available online for viewing during the lunch break.