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Machine Learning Modeling for ABC Transporter Efflux and Inhibition

Daood NJ, Carey SR, Chung E, Wang T, Kreutz A, Girireddy M, Chakravarti S, Kleinstreuer NC, Tiley JB, Aleksunes LM, Zhu H. 2025. Mol. Pharm.

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Maternal Organophosphate Pesticide Exposure in Relation to Birthweight: Modification by Placenta Transporter Genotype

Nguyen DQ, Hyman S, Medley E, Bozack AK, Kahn LG, Kannan K, Guitierrez A, Aleksunes LM, Rivera-Núñez Z, Cowell W. 2025. Placenta.

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Developmental Toxicity: Artificial Intelligence-Powered Assessments

Wang T, Jia X, Aleksunes LM, Shen H, Deng HW, Zhu H. 2025. Trends Pharmacol Sci.

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Current Approaches and Advances in Placental Toxicology

Veiga-Lopez A, Elkin ER, Harris SM, Blake BE, Paquette AG, Aleksunes LM, Stapleton PA. 2025. Trends Endocrinol Metabolism.

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Mycoestrogen Exposure during Pregnancy: Impact of the ABCG2 Q141K Variant on Birth and Placental Outcomes

Rivera-Núñez Z, Kinkade C, Brinker A, Zhang R, Buckley B, Brunner J, Ohman-Strickland P, Qiu X, Qasem RJ, Fallon JK, Smith PC, Miller RK, Salafia CS, O’Connor TG, Aleksunes LM, Barrett ES. 2025, Environ Health Perspective

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Protective Role of the Placental Efflux Transporter BCRP/ABCG2 in the Relationship Between Prenatal Cadmium Exposure, Placenta Weight, and Size at Birth

Barrett ES, Rivera-Núñez Z, Getz K, Ohman-Strickland P, Zhang R, Kozlosky D, Doherty CL, Buckley BT, Brunner J, Miller RK, O’Connor TG, Aleksunes LM. 2023, Environmental Research

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Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter

 

Kozlosky D, Doherty C, Buckley B, Goedken MJ, Miller RK, Huh DD, Barrett ES, Aleksunes LM. 2024, Toxicological Sciences

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Impact of Pregnancy Related Hormones on Drug Metabolizing Enzyme and Transport Protein Concentrations in Human Hepatocytes

Fashe MM, Fallon JK, Miner TA, Tiley JB, Smith PC, Lee CR., 2022, Frontiers in Pharmacology

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A Microphysiological Model of Human Trophoblast Invasion During Implantation

 

Park JY, Mani S, Clair G, Olson HM, Paurus VL, Ansong CK, Blundell C, Young R, Kanter J, Gordon S, Yi AY, Mainigi M, Huh DD, 2022, Nature Communications

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Cohort Profile: Understanding Pregnancy Signals and Infant Development (UPSIDE): a Pregnancy Cohort Study on Prenatal Exposure Mechanisms for Child Health

O’Connor T, Best M, Brunner J, Ciesla AA, Cunning A, Kapula N, Kautz A, Khoury L, Macomber A, Meng Y, Miller RK, Murphy H, Salafia CM, Vallejo Sefair A, Serrano J, Barrett E, UPSIDE study, 2021, BMJ Open

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Predictive Modeling of Estrogen Receptor Agonism, Antagonism, and Binding Activities Using Machine- and Deep-Learning Approaches

Ciallella HL, Russo DP, Sharma S, Li Y, Sloter E, Sweet L, Huang H, Zhu H., 2021, Laboratory Investigation

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Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier

Blundell C, Yi YS, Ma L, Tess ER, Farrell MJ, Georgescu A, Aleksunes LM, Huh D, 2018, Advances in Healthcare Materials

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