Publications
Membrane Transporters in Drug Development and as Determinants of Precision Medicine
Aleksandra Galetin, Kim L. R. Brouwer, Donald Tweedie, Kenta Yoshida, Noora Sjöstedt, Lauren Aleksunes, Xiaoyan Chu, Raymond Evers, Michael J. Hafey, Yurong Lai, Pär Matsson, Andrew Riselli, Hong Shen, Alex Sparreboom, Manthena V. S. Varma, Jia Yang, Xinning Yang, Sook Wah Yee, Maciej J. Zamek-Gliszczynski, Lei Zhang, & Kathleen M. Giacomini, 2024 Nature Reviews Drug Discovery
Placental BCRP Transporter Reduces Cadmium Accumulation and Toxicity in Immortalized Human Trophoblasts
Ranran Zhang, Lauren Walker, Xia Wen, Cathleen Doherty, Ludwik Gorczyca, Brian Buckley, Emily Barrett, Lauren Aleksunes, 2023, Reproductive Toxicology
Protective Role of the Placental Efflux Transporter BCRP/ABCG2 in the Relationship Between Prenatal Cadmium Exposure, Placenta Weight, and Size at Birth
Emily Barrett, Zorimar Rivera-Núñez , Kylie Getz, Pamela Ohman-Strickland, Ranran Zhang, Danielle Kozlosky, Cathleen Doherty, Brian Buckley, Jessica Brunner, Richard Miller, Thomas O’Connor, Lauren Aleksunes, 2023, Environmental Research
Fetoplacental Disposition and Toxicity of Cadmium in Mice Lacking the Bcrp Transporter
Danielle Kozlosky, Cathleen Doherty, Brian Buckley, Michael Goedken, Richard Miller, Dan Dongeun Huh, Emily Barrett, Lauren Aleksunes, 2024, Toxicological Sciences
Impact of Pregnancy Related Hormones on Drug Metabolizing Enzyme and Transport Protein Concentrations in Human Hepatocytes
Muluneh M. Fashe, John K. Fallon, Taryn A. Miner, Jacqueline B. Tiley, Philip C. Smith and Craig R. Lee, 2022, Frontiers in Pharmacology
A Microphysiological Model of Human Trophoblast Invasion During Implantation
Ju Young Park, Sneha Mani, Geremy Clair , Heather M. Olson, Vanessa L. Paurus, Charles K. Ansong, Cassidy Blundell, Rachel Young, Jessica Kanter, Scott Gordon, Alex Y. Yi, Monica Mainigi, Dan Huh, 2022, Nature Communications
Cohort Profile: Understanding Pregnancy Signals and Infant Development (UPSIDE): a Pregnancy Cohort Study on Prenatal Exposure Mechanisms for Child Health
Thomas O’Connor, Meghan Best, Jessica Brunner, Allison Avrich Ciesla, Allison Cunning, Ntemena Kapula, Amber Kautz, Leena Khoury, Allison Macomber, Ying Meng, Richard K Miller, Hannah Murphy, Carolyn M Salafia, Ana Vallejo Sefair, Jishyra Serrano, Emily Barrett, UPSIDE study, 2021, BMJ Open
Predictive Modeling of Estrogen Receptor Agonism, Antagonism, and Binding Activities Using Machine- and Deep-Learning Approaches
Heather L. Ciallella, Daniel P. Russo, Lauren M. Aleksunes, Fabian A. Grimm, Hao Zhu, 2021, Laboratory Investigation
Placental Drug Transport-on-a-Chip: A Microengineered In Vitro Model of Transporter-Mediated Drug Efflux in the Human Placental Barrier
Cassidy Blundell, Yoon-Suk Yi, Lin Ma, Emily R. Tess, Megan J. Farrell, Andrei Georgescu, Lauren M. Aleksunes, and Dongeun Huh, 2018, Advances in Healthcare Materials