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LDD Publications

Research Articles (peer-reviewed)

  1. Michniak, B. Recent advances in antiperspirant research. Cosmetic Technology (1980) 2, (11), 34-39.
  2. Michniak, B. Do we undervalue the importance of pharmacy management courses at the undergraduate level? J. Instit. Pharm. Manag. Int. (1980) 2, (1), 12-13.
  3. Michniak, B. Studies on the mechanism of topical anhidrosis due to polyvalent cations. Inter. J. Cosm. Sci. (1981) 3, (1), 29-36. Paper received “1981 Best Publication Prize” from the Society of Cosmetic Scientists. PMID 19469924.
  4. Michniak, B. Perspiration, antiperspirants and deodorants. Pharm. J. (1982) 228, 452-453.
  5. Michniak, B. Pharmacy management courses in the United States: a study. J. Instit. Pharm. Manag. Int. (1982), 4, (3), 12-13.
  6. Michniak, B. Advances in topical corticosteroid therapy. Int. J. Cosm. Sci. (1983) 5, (6), 277-291. PMID 19469995.
  7.  Michniak, B. A new approach to assessing sweat production. Int. J. Cosm. Sci. (1983), 5, (6), 267-275. PMID 19469994.
  8.  Michniak-Mikolajczak, B. Sweat production in the isolated rat eccrine sweat gland. Brit. J. Derm. (1984), 111 (3), 309-314. PMID 6383449.
  9. Michniak-Mikolajczak, B. Investigation of the presence of intercellular canaliculi in human and rat eccrine sweat glands. Patalogia Polska (in English) (1984) 35 (4) 517-522.
  10. Michniak, B. Investigation of sweat production in the isolated rat eccrine sweat gland. Pat. Pol. (in English) (1984) 35 (2), 231-238.
  11. Michniak-Mikolajczak, B. Dermatological preparations: problems of efficacy. College of Pharmacy Practice Corresp. J. (1984) 4, 9-13.
  12. Michniak-Mikolajczak, B. Skin: Nature’s barrier to topical preparations? College of Pharmacy Practice Corresp. J. (1984), March (3), 20-21.
  13. Michniak-Mikolajczak, B. Bodor, N. A study of the penetration of five novel synthetic steroids through hairless mouse skin in vitro. Int. J. Cosm. Sci. (1985) 7, 175-179. PMID 19460025.
  14. Michniak-Mikolajczak, B. An in vitro investigation of the astringency property of certain anhidrotic solutions. Polish J. Pharmac. Pharm. (in English) (1985) 37, 141-145. PMID 4048009.
  15. Michniak-Mikolajczak, B., Barry, B.W., Waller, I.L. A microbalance technique for measuring water vapour uptake and release by stratum corneum in vitro. Int. J. Pharm. (1986) 31, (3) 247-260.
  16. Michniak, B.B., Chapman, J.M. Comparison of percutaneous penetration in vitro using clofibric acid esters and amides as novel enhancers in two species: mouse and guinea pig. Int. J. Cosm. Sci. (1992), 14, 153-161. PMID 19272103.
  17. Michniak, B.B., Chapman, J.M., Seyda, K.L. Facilitated transport of two model steroids by esters and amides of clofibric acid. J. Pharm. Sci. (1993) 82, (2) 214-219. PMID 8445538.
  18. Michniak, B.B., Seyda, K.L. A simple and specific high liquid chromatography method for the assay of a series of novel dermal penetration enhancers. Int. J. Cosm. Sci. (1993) 15, 7-13. PMID 19272115.
  19. Michniak, B.B., Player, M.R., Chapman, J.M., Jr., Sowell, J.W., Sr. In vitro evaluation of a series of Azone analogs as dermal penetration enhancers I. Int. J. Pharm. (1993) 91, 85-93.
  20. Michniak, B.B., Player, M.R., Fuhrman, L.C., Christensen, C.A., Chapman, J.M., Jr., Sowell, J.W., Sr. In vitro evaluation of a series of Azone analogs as dermal penetration enhancers II. (Thio)amides. Int. J. Pharm. (1993) 94 203-210.
  21. Michniak, B., Chapman, J. Transdermal delivery of indomethacin and levonorgestrel using clofibric acid amides as penetration enhancers. Drug Delivery (1993) 1 (1) 35-41.
  22. Michniak, B.B., Player, M.R., Fuhrman, L.C., Christensen, C.A., Chapman, J.M., Jr., Sowell, J.W., Sr. In vitro evaluation of a series of Azone analogs as dermal penetration enhancers III. Acyclic amides. Int. J. Pharm. (1994) 110, 231-239.
  23. Michniak, B.B., Player, M.R., Chapman, J.M., and Sowell, J.W. Azone analogues as penetration enhancers: effect of different vehicles on hydrocortisone acetate skin permeation and retention. J. Controll. Rel. (1994) 32, 147-154.
  24. Michniak, B.B., Player, M.R., Godwin, D.A., Phillips, C.A., and Sowell, J.W., Sr. In vitro evaluation of a series of Azone analogs as dermal penetration enhancers IV. Amines. Int. J. Pharm. (1995), 116, 201-209.
  25. Michniak, B.B., Player, M.R., Godwin, D.A., and Sowell, J.W., Sr. Investigation of enhancer-structure activity relationships in congeners of 2-(1-nonyl)-1,3-dioxolane. Drug Delivery (1995) 2, 117-122.
  26. Phillips, C.A. and Michniak, B.B. Topical application of Azone analogs to hairless mouse skin: a histopathological study. Int. J. Pharm. (1995), 125, 63-71.
  27. Phillips, C.A. and Michniak, B.B. Transdermal delivery of drugs with differing lipophilicities using Azone analogs as dermal penetration enhancers. J. Pharm. Sci. (1995), 84 (12), 1427-1433. PMID 8748324.
  28. Michniak, B. Beauty is only skin deep. Cosmetic Horizons, Jan. (1995), pp. 2 and 4.
  29. Michniak, B. Skin aging and preventive treatment. Cosmetic Horizons, March (1995), pp. 2 and 4.
  30. Michniak, B. Moisturizing and the skin. Cosmetic Horizons, April (1995), pp. 2 and 4.
  31. Michniak, B., Player, M.R., and Sowell, Sr., J.W. Synthesis of and in vitro transdermal penetration enhancing activity of lactam-N-acetic acid esters. J. Pharm. Sci. (1996), 85 (2), 150-154.
  32. Fincher, T.K., Yoo, S.D., Player, M.R., Sowell, Sr., J.W., and Michniak, B.B. In vitro evaluation of a series of N-dodecanoyl-L-amino acid methyl esters as dermal penetration enhancers. J. Pharm. Sci. (1996), 85 (9), 920-923. PMID 8877879.
  33. Fuhrman, Jr., L.C., Michniak, B.B., Behl, C.R., and Malick, A.W. Effect of novel penetration enhancers on the transdermal delivery of hydrocortisone: an in vitro species comparison. J. Controlled Release (1996) 45 (2), 197-204.
  34. Hunter, D.A., Yoo, S.D., Fox, J.L., and Michniak, B.B. Stability of albuterol in continuous nebulization. Int. J. of Pharmaceutical Compounding (1998), 2 (5), 394-396. PMID 23989706.
  35. Godwin, D.A., Michniak, B.B., Player, M.R., and Sowell, Sr., J.W. Transdermal and dermal enhancing activity of pyrrolidinones in hairless mouse skin. Int. J. Pharm. (1997), 155(2), 241-250.
  36. Godwin, D.A., Michniak, B.B., and Creek, K. Evaluation of transdermal penetration enhancers using a novel skin alternative. J. Pharm. Sci. (1997), 86 (9), 1001-1005. PMID 9294812.
  37. Michniak, B.B., Player, M.R., Godwin, D.A., Lockhart, C.C., and Sowell, Sr., J.W. In vitro evaluation of a series of Azone analogues as dermal penetration enhancers. V. Miscellaneous compounds. Int. J. Pharm. (1998), 161, 169-178.
  38. Godwin, D.A., Player, M.R., Sowell, Sr., J.W., and Michniak, B.B. Investigation of novel urea compounds as transdermal penetration enhancers. Int. J. Pharm. (1998) 167 (1-2), 165-175.
  39. Godwin, D.A. and Michniak, B.B. Influence of drug lipophilicity on terpenes as transdermal penetration enhancers. Drug Develop. and Industrial Pharmacy (1999) 25 (8), 905-915. PMID 10434134.
  40. Michniak, B.B. Therapeutic protein, semisolid dosage forms and dermatopharmaceuticals. IDrugs (1999), 2 (1), 29-30. PMID 16180165.
  41. Strekowski, L., Henary, M., Kim, N., Michniak, B. N- (4-Bromobenzoyl)-S,S,-dimethyliminosulfurane, a potent dermal penetration enhancer. Bioorganic and Medicinal Chemistry Letters (1999), 9,1033-1034. PMID 10230634.
  42. Asbill, C.S., Kim, N., Creek, C.E., and Michniak, B.B. Comparison of transdermal penetration through human bioengineered skin, human skin and hairless mouse skin. 18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC. May 20-23, 1999. Critical Reviews in Biomedical Engineering (1999), 26,406-407.
  43. Al-Khalili, M., Kim, N., and Michniak, B.B. Comparison between hairless mouse skin and hairless Peromyscus Maniculatus as in vitro skin models. 18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC. May 20-23, 1999. Critical Reviews in Biomedical Engineering (1999), 26, 411-412.
  44. El-Kattan, A. and Michniak, B.B. Effect of zinc sulfate formulations on the permeation of zinc in human cadaver skin. 18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC. May 20-23, 1999. Critical Reviews in Biomedical Engineering (1999), 26, 410-411.
  45. El-Kattan, A.F., Asbill, C.S., Michniak, B.B. The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems. International Journal of Pharmaceutics (2000), 198 (2), 179-189. PMID 10767567.
  46. Kim, N., El-Khalili, M., Henary, M.M., Strekowski, L., Michniak, B. Percutaneous penetration enhancement activity of aromatic S,S- dimethyliminosulfuranes. International Journal of Pharmaceutics, 1999, 187, 219-229. PMID 10502628.
  47. Asbill, C.A., Kim, N., El-Kattan, A., Creek, K., Wertz, P., Michniak, B.B. Evaluation of a human bioengineered skin equivalent for drug permeation studies. Pharmaceutical Research, 2000, 17 (9), 1092-1097. PMID 11087041.
  48. Asbill, C.S., El-Kattan, A.F., Michniak, B.B. Enhancement of transdermal drug delivery: Chemical and Physical approaches. Critical Reviews in Therapeutic Drug Carrier Systems, (2000), 17 (6), 621-658. PMID 11204737.
  49. Asbill, C.S. Michniak, B.B. Percutaneous penetration enhancers: local versus transdermal activity. Pharm.Sci. Technolo Today (2000) 3 (1), 36-41. PMID 10637599.
  50. El-Kattan, A. and Michniak, B.B. Effect of formulation variables on the percutaneous permeation of ketoprofen from gel formulations. Drug Delivery, 2000, 7, 147-153. PMID 10989915.
  51. Holladay, J.W., Dewey, M.J., Michniak, B.B., Wiltshire, H., Halberg, D.L., Weigl, P., Liang, Z., Halifax, K., Lindup, W.E., Back, D.J. Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir. Drug Metabolism & Disposition, 2001, March, 29 (3), 299-303. PMID 11181499.
  52. Kim, N., El-Kattan, A., Asbill, C.S., Kennette, R.J., Sowell, J.W. Sr., Latour, R., Michniak, B.B. Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine) hexahydro-1H-azepine-2-one as dermal penetration enhancers: side chain length variation and molecular modeling. Journal of Controlled Release, 2001, 73,183-196. PMID 11516496.
  53. El-Kattan, A.F., Asbill, C.S., Kim, N., Michniak, B.B. The effect of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities. International Journal of Pharmaceutics, 2001, 215, 229-240. PMID 11250108.
  54. Wang, Y., Fan, Q., Song, Y., Michniak, B. Effect of fatty acids and iontophoresis on the delivery of midodrine hydrochloride and structure of human skin. Pharm. Research 2003, 20 (10), 1612-1618. PMID 14620516.
  55. Al-Khalili, M., Meidan, V., Michniak, B. Iontophoretic transdermal delivery of buspirone hydrochloride in hairless mouse skin. AAPS Pharm. Sci., 2003, 5 (2), article 14 at http://www.pharmsci.org. PMID 12866941.
  56. Meidan, V., Al-Khalili, M., Michniak, B. Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers. Int. J. Pharm., 2003, 264,73-83. PMID 12972337.
  57. Bourke, S., Al-Khalili, M., Michniak, B., Kohn, J., Poole-Warren, L. A photo cross-linked poly(vinyl alcohol) hydrogel growth factor release vehicle for wound healing applications. AAPS PharmSci, 2003; 5 (4) E33; Article 33 (http://www.aapspharmsci.org) 11 pages. PMID 15198521.
  58. Djordevic, J., Michniak, B., Uhrich, K.E. Amphiphilic star-like macromolecules as novel carriers for topical delivery of non-steroidal anti-inflammatory drugs. AAPS PharmSci, 2003; 5 (4) Article 26 (http://www.pharmsci.org). pp. 256-267. PMID 15198514.
  59. Meidan, V. M., Michniak, B.B. Emerging Technologies in Transdermal Therapeutics. Amer. J. Ther. 2004, 11 (4), 312-6. PMID 15266225.
  60. Song, Y., Wang, Y., Thakur, R., Meidan, V.M., Michniak, B. Mucosal drug delivery: Membranes, Mechanisms and Applications. Critical Reviews in Therapeutic Drug Carrier Systems, 2004, 21 (3), 195-256. PMID 15248809.
  61. Fan, Q., Sirkar, K.K., Wang, Y. and Michniak, B.B. In vitro delivery of doxycycline hydrochloride based on a porous membrane-based aqueous-organic partitioning system. Journal of Controlled Release, 2004, 98, 355-365. PMID 15312992.
  62. Wang, Y., Thakur, R., Fan, Q., Michniak, B.B. Transdermal iontophoresis: Combination strategies to improve transdermal iontophoretic drug delivery. European J. of Pharmaceutics & Biopharmaceutics (2005), 60, 179-191. PMID 15939232.
  63. Pugh, W.J., Wong, R., Falson, F., Michniak, B.B. Moss, G.P. Discriminant analysis as a toll to identify compounds with potential as transdermal enhancers. J. Pharm. Pharmacol., 2005, 57 (11), 1389-96. PMID 16259770.
  64. Song, Y., Xiao, C., Mendelsohn, R., Zheng, T., Strekowski, L., Michniak, B.B. Investigation of iminosulfuranes as novel transdermal penetration enhancers: enhancement activity and cytotoxicity. Pharm. Research (2005), 22 (11), 1918-1925. PMID 16132348.
  65. Barrow, D.J., Chandrasekaran, S., Heerklotz, H.H., Henary, M.M., Michniak, B.B., Nguyen, P.M. Song, Y., Smith, J.C., Strekowski, L. Mechanistic studies on percutaneous penetration enhancement by N-(4-halobenzoyl)-S,S,-dimethyliminosulfuranes. Journal of Lipid Research (2005), 46, 2192-2201. PMID 16061953.
  66. Meidan, V., Bonner, M.C. and Michniak, B.B. Transfollicular drug delivery: is it a reality? Int. Journal of Pharmaceutics, (2005), 306, 1-14. PMID 16260102.
  67. Batheja, P., Thakur, R., Michniak, B. Transdermal Iontophoresis. Expert Opinion in Drug Delivery (2006), 3 (1), 127-138. PMID 16370945.
  68. Simon, L., Weltner, A.N., Wang, Y., Michniak, B. A parametric study of iontophoretic transdermal drug delivery systems. Journal of Membrane Sciences, (2006), 278,124-132.
  69. Wang, Y., Wang, Y., Yang, J., Pfeffer, R., Dave, R., Michniak, B. The application of a supercritical antisolvent process for sustained drug delivery. Powder Technology (2006), 164, 94-102.
  70. Goyal, A., Mandapuram, S., Michniak, B., Simon, L. Application of orthogonal collocation and regression techniques for recovering parameters of a two-pathway transdermal drug delivery model. Computers & Chemical Engineering (2007), 31, 107-120.
  71. Dayan, N., Batheja, P., Michniak, B. Physical characteristics and skin penetration of lecithin-oleic acid lamellar delivery system. Cosmetics & Toiletries (2007), 122 (9), 73-82.
  72. Thakur, R., Meidan, V., Michniak, B. Transdermal and buccal delivery of methylxanthines through human tissue in vitro. Drug Develop. & Ind. Pharmacy (2007), 33, 513-521. PMID 17520442.
  73. Pensack, R.D., Michniak, B.B., Moore, D., Mendelsohn, R. Infrared kinetic/structural studies of barrier reformation in intact stratum corneum following thermal perturbation. Applied Spectroscopy, (2006) 60 (12), 1399-1404. PMID 17217589.
  74. Sheihet, L., Chandra, P., Batheja, P., Devore, D., Kohn, J., Michniak, B. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int. J. Pharmaceutics, (2008), 350, 312-319. PMID 17897801.
  75. Batheja, P., Kaushik, D., Hu, L., Michniak, B. Transdermal iontophoresis. Drug Delivery, (2007), pp.46-48.
  76. Kaushik, D., Batheja, P., Kilfoyle, B., Rai, V., Michniak-Kohn, B. Percutaneous Penetration modifiers: enhancement vs. retardation. Expert Opinion on Drug Delivery, (2008), May 5 (5), 517-529.
  77. Thakur, R.A., Florek, C.A., Kohn, J., Michniak, B. Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing. International J. of Pharmaceutics, (2008), 364, 87-93. PMID 18771719.
  78. Fan, Q., Sirkar, K.L., Michniak, B. Iontophoretic transdermal drug delivery system using a conducting polymeric membrane. J. Membrane Science, (2008), 321, 240-249.
  79. Sintov, A.C., Zhang, P., Michniak-Kohn, B.B. Cutaneous biotransformation of N-(4-bromobenzoyl)-S, S-dimethyliminosulfurane and its product, 4-bromobenzamide, leading to percutaneous penetration enhancement of drugs: initial evidence using hydrocortisone. J. Controlled Release, (2009), 133, 44-51.
  80. Cheuvront, S.N., Ely, B.R., Kenefick, R.W., Michniak-Kohn, B., Rood, J., Sawka, M.N. No effect of nutritional adenosine receptor antagonists on exercise performance in the heat. American J. Physiology Regulatory Integrative & Comparative Physiology (2008), 296 (2), 394-401.
  81. Ganio, M.S., Armstrong, L.E., Johnson, E. C., Klau, J.F., Ballard, K., Casa, D.J., Michniak-Kohn, B., Kaushik, D., Maresh, C.M. Effect of quercetin supplementation on maximal aerobic capacity. Journal of Sports Science (2010), 28 (2), 201-208.
  82. Murthy, N.S., Bedoui, F., Kilfoyle, B., Iovine, C., Michniak-Kohn, B., Kohn, J. Monitoring thickness and viscoelastic properties of skin in liquid environments using quartz crystal microbalance. J. Pharm. Sci., (2011) 100 (2), 530-535.
  83. Batheja, P., Song, Y., Wertz, P., Michniak-Kohn, B. Effects of growth conditions on the barrier properties of a human skin equivalent. Pharm. Research (2009), 26 (7), 1689-1700.
  84. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects: Part I. International J. of Pharmaceutics (2010), 386, 42-51.
  85. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects: Thermal and Spectral Analyses. AAPS Pharm Sci. Tech. (2010) Sept. 11 (3) 1068-83.
  86. Rai, V., Ghosh, I., Bose, S., Silva, S.M.C., Chandra, P., Michniak-Kohn, B.A transdermal review on permeation of drug formulations, modifier compounds and delivery methods. J. Drug Delivery Science & Technology (2010) 20 (2), 75-87.
  87. Valenzuela, L., Michniak, B., Kohn, J. Variability of water uptake studies of biomedical polymers, Journal of Applied Polymer Science (2011), n/a. doi: 10.1002/app.33485, and (2011), 121, 1311-1320.
  88. Pingali, K., Mendez, R., Lewis, D., Michniak-Kohn, B., Muzzio, F. Mixing order of silica and magnesium stearate-Influence on powder and tablet properties, International Journal of Pharmaceutics (2011), 409 (1-2), 269-277.
  89. Pingali, K. Mendez, R. Lewis, D., Michniak-Kohn, B., Cuitino, A., Muzzio, F. Evaluation of strain induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions, Drug Development and Industrial Pharmacy (2010), Early Online, 1-9 and (2011), 37 (4), 428-435.
  90. Kaushik, D., O’Fallon, K., Clarkson, P., Dunne, C.P., Conca, K.R., Michniak-Kohn, B. Comparison of quercetin pharmacokinetics following oral and buccal supplementation in humans. Journal of Food Science, (2012), Oct 24. Doi: 10.111/j.1750-3841.2012.02934.x. [Epub ahead of print] PMID: 23094941 and (2012) Vol. 77 (11), November, pp. H 231-238. PMID 23094941.
  91. Rai, V., Terebetski, J., Silva, S., Michniak-Kohn, B. Human Skin Equivalents (HSEs) as an alternative for transdermal permeation, phototoxicity and cytotoxicity studies. Transdermal (2010), 2 (3) May, 5-8.
  92. Falcone, R., Michniak-Kohn, B. Under the Skin. Pharmaceutical Manufacturing and Packing Sourcer, (2010), May, pp. 26-31.
  93. Batheja, P. Sheihet, L., Kohn, J., Singer, A., Michniak-Kohn, B. Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo distribution studies. Journal of Controlled Release (2011) 149, 159-167 and (2010), doi:10.1016/j/jconrel.2010.10.005.
  94. Hu, L., Michniak-Kohn, B. Enhanced in vitro transbuccal drug delivery of ondansetron HCl. International J. of Pharmaceutics, (2011) 404, 66-74; doi:10.1016/j.ijpharm. 2010.10.052.
  95. Michniak-Kohn, B. and Shah, K.R. Patchless transdermal drug delivery. Transdermals, 2011 (March), pp. 5-11.
  96. Rai, V., Dayan, N., Michniak-Kohn, B. A comparative evaluation of photo-toxic effect of fractionated melanin and its relationship to cell protection activity in different cell lines. Toxicity In Vitro (2011), 25, 538-544 and doi: 10.1016/j.tiv.2010.11.017 2010 EPublication.
  97. Rai, V., Tan, H.S., Michniak-Kohn, B. Effect of pre-formulation parameters on permeation of naltrexone (NTX)- HCl across buccal mucosa. Int. J. Pharm. (2011), 411, 92-97 and doi: 10.1016/j.ijpharm.2011.03.046.
  98. Meng, X., Yang, D., Keyvan, G., Michniak-Kohn, B., Mitra, S. Synthesis and immobilization of microscale drug particles in polymeric films, (2011), Colloids and Surfaces B.: Biointerfaces (2011), 86 (1), 181-188.
  99. Hu, L., Silva, S.M.C., Damaj, B.B., Martin, R., Michniak-Kohn, B.B. Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches. Int. J. Pharm., (2011), 421, 53-62 and doi: 10.1016/j.ijpharm.2010.10.052.
  100.  Zhang, J., Michniak-Kohn, B. Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine and caffeine. International Journal of Pharmaceutics (2011), 421, 34-44.
  101. Wei, R., Simon, L., Hu, L., Michniak-Kohn, B. Effects of iontophoresis and chemical enhancers on the transport of lidocaine and nicotine across buccal mucosa. Pharmaceutical Research, (2012), 29 (4), 961-971.
  102. Ghosh, I., Michniak-Kohn, B. A comparative study of Vitamin E TPGS/HPMC supersaturated system and other solubilizer/ polymer combinations to enhance the permeability of a poorly soluble drug through the skin. Drug Development & Industrial Pharmacy (2012), doi:10.3109/03639045.2011.653363.
  103. Sievens-Figueroa, L., Bhakay, A., Jerez-Rozo, J.I., Pandya, N., Romanach, R., Michniak-Kohn, B., Iqbal, Z., Biligili, E., Dave, R. Preparation and characterization of hydroxypropyl methyl cellulose films containing stable BCS Class II drug nanoparticles for pharmaceutical applications. Int. J. Pharmaceutics (2012), 423, 496-508. Listed as one of top 25 most downloaded articles for 2012 from Int. J. Pharm. Sci.
  104. Silva, S.M.C., Hu, L. Sousa, J.J.S., Pais, A.A.C.C., Michniak-Kohn, B. A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondrasetron HCl and diltiazem HCl. European Journal of Pharmaceutics and Biopharmaceutics (2011), doi: 10.1016/j.ejpb.2011.11.010 and (2012), 80, 663-673.
  105. Valenzuela, L.M., Zhang, G., Flach, C., Murthy, S., Mendelsohn, R., Michniak-Kohn, B., Kohn, J. Multiscale analysis of water uptake and erosion in biodegradable polyarylates. Polymer Degradation & Stability (2012), 97, 410-420.
  106.  Zheng, Z., Michniak-Kohn, B. Tissue Engineered Human Skin Equivalents. Pharmaceutics ISSN 1999-4923 www.mdpi.com/journal/pharmaceutics doi: 10.3390/pharmaceutics4010026, (2012), 4, 26-41.
  107. Meng, X., Yang, D., Keyvan, G., Michniak-Kohn, B., Mitra, S. Synthesis and immobilization of micro-scale drug particles in presence of cyclodextrins. Colloids and Surfaces B: Biointerfaces (2011), doi:10.1016/j.colsurfb.2011.11.043.
  108. Elele, E., Shen, Y., Susalrla, R., Khusid, B., Keyvan, G., Michniak-Kohn, B. Electrodeless electro-hydrodynamic drop-on-demand encapsulation of drugs into porous polymer films for fabrication of personalized dosage units. Journal of Pharmaceutical Sciences (2012), doi 10.1002/jps.23165.
  109. Ghosh, I., Michniak-Kohn, B. Design and characterization of submicron formulation for a poorly soluble drug: The effect of Vitamin E TPGS and other solubilizers on skin permeability enhancement. International J. of Pharmaceutics (2012), 434, 90-98.
  110. Rahman, A., Frenchek, S., Kilfoyle, B., Patterkine, L., Rahman, A., Michniak-Kohn, B. Diffusion kinetics and permeation concentration of human stratum corneum characterization by terahertz scanning reflectometry. Drug Development & Delivery (2012), May, Vol. 12 (4), pp.43-49.
  111. Sharp, M.A., Hendrickson, N.R., Staab, J.S., McClung, H.L., Nindl, B.C., Michniak-Kohn, B. Effects of short-term quercetin supplementation on soldier performance. The Journal of Strength & Conditioning Research, 2012, 26 (7), S53-60.
  112. O’Fallon, K. S., Kaushik, D., Michniak-Kohn, B., Dunne, C.P., Zambraski, E.J., Clarkson, P.M. Effects of quercetin supplementation on markers of muscle damage and inflammation after eccentric exercise. Int. J. Sport Nutr. Exerc. Metab. 2012, Dec. 22, (6), 430-437. Epub. 2012, Jul 4. PMID 23090112.
  113. Kilfoyle, B.E., Sheihet, L., Zheng, Z., Laohoo, M., Kohn, J., Michniak-Kohn, B. Development of paclitaxel-TyroSpheres for topical skin treatment. Journal of Controlled Release (2012), 163, 18-24 and doi:10.1016/j.jconrel.2012.06.021.
  114. Ghosh, I., Michniak-Kohn, B. Influence of critical parameters of nanosuspension formulation on the permeability of a poorly soluble drug through the skin-A case Study. AAPS- Pharm. Tech. (2013), doi: 10:1208/s12249-013-9995-4. PMID 23824877.
  115. Bose, S., Du, Y., Takhistov, P., Michniak-Kohn, B. Formulation optimization and topical delivery of quercetin from solid lipid based nanosystems. Int. J. Pharmaceutics (2013), 441, 56-66. PMID 23262430.
  116. Sievens-Figueroa, L., Pandya, N., Bhakay, A., Keyvan, G., Michniak-Kohn, B., Bilgili, E., Dave, R.N. Using USP I and USP IV for discriminating dissolution rates of nano- and microparticle-loaded pharmaceutical strip films. AAPS PharmSciTech. (2012), Dec., 13 (4), 1473-82. PMID 23090112.
  117. Bose, S., Michniak-Kohn, B. Preparation and characterization of lipid based nanosystems for topical delivery of quercetin. European J. Pharm. Sci. (2012) Dec 13. doi:pii: S0928-0987(12)00477-0. 10.1016/j.ejps.2012.12.005. [Epub ahead of print] and (2013), 48, 442-452. PMID 23246734.
  118. Zhang, Z., Tsai, P., Ramezanli, T., Michniak-Kohn, B. Polymeric nanoparticle-based topical delivery systems for the treatment of dermatological conditions. WIREs Nanomedicine & Nanobiotechnology (2013), doi: 10.1002/wnan.1211 and May-June; 5 (3), 205-218. PMID 23386536.
  119. Susarla, R., Sievens-Figueroa, L., Bhakay, A., Shen, Y., Jerez-Rozo, J. L., Engen, W., Khusid, B., Biligili, E., Romanach, R., Morris, K.R., Michniak-Kohn, B., Dave, R. N. Fast drying of biocompatible polymer films loaded with poorly water soluble drugs nano-particles via low temperature forced convection. Int. J. Pharm. (2013), 445, 93-103. PMID 23911341.
  120. Zhang, Z., Kilfoyle, B., Sheihet, L., Kohn, J. Michniak-Kohn, B. Novel nanospheres that deliver actives to skin layers. Proceedings of the 21st COLAMIQC (Congreso Latinoamericano e Iberico de Quimicos Cosmeticos) Transamerica Expo Center, Sao Paolo, Brazil, May 14-16th 2013.
  121. Silva, S. M.C., Sousa, J. J. S., Marques, E., Pais, A.A.C.C., Michniak-Kohn, B.B. Structure activity relationships in alkylammonium C12-gemini surfactants used as dermal enhancers. AAPS Journal, 2013, DOI: 10.1208/s12248-013-9518-y. Published on line 20 August 2013 and 2013, Oct.; 15 (4), 1119-1127. PMID 23959685.
  122. Sun, X.L., Tsai, P., Bhat, R., Bonder, E. M., Michniak-Kohn, B., Pietrangelo, A. Thermoresponsive block copolymer micelles with tunable pyrrolidone-based polymer cores: Structure/Property correlations and application as drug carriers. Journal of Materials Chemistry B (2015), 3, 814-823.
  123. Terebetski, J. and Michniak-Kohn, B. Combining Ibuprofen Sodium with Cellulosic Polymers: A Deep Dive into Mechanisms of Prolonged Supersaturation. Int. J. Pharm. (2014), 475 (1-2), 536-546. PMID 25219860.
  124. Terebetski, J. Cummings, J. J., Fauty, S.E. and Michniak-Kohn, B. Combined use of crystalline sodium salt and polymeric precipitation inhibitors to improve pharmacokinetic profile of ibuprofen through supersaturation. AAPS Pharm. Sci.Tech. (2014), 15 (5), 1334-1344. PMID 24920524.
  125. Palma, F., Michniak-Kohn, B., Perez-Correa, J.R., Hernandez, E., Romanach, R., Valenzuela, L.M. Near-infrared chemical imaging and its correlation with the mechanical properties of chitosan-gelatin edible films. Carbohydrate Polymers (2016), 136, 409-417; http://dx.doi.org/10.1016/j.carbpol.2015.09.051. PMID 26572371.
  126. Dorrani, M., Kaul, M., Pilch, D., Parhi, A., LaVoie, E.J., Michniak-Kohn, B. TXA497 as a topical antibacterial agent: Comparative anti-Staphylococcal, skin deposition, and skin permeation studies with mucipirocin. Int J. Pharmaceutics (2014), 476, 199-204. PMID 25263100.
  127. Tsai, P., Lee, S. and Michniak-Kohn, B. In Vitro Methods for Screening Transdermal Formulations. Therapeutic Delivery-Special Focus edition of journal- Advances and Challenges in Transdermal Drug Delivery (2015), 6 (9), 1043-1052. Sept. 30 [Epub. ahead of print] PMID 26419344.
  128. Bhat, R., Tsai, P., Sun, X.-L., Daoud, D., Lalancette, R.A., Michniak-Kohn, B., Pietrangelo, A. Effect of residue structure on the thermal and thermoresponsive properties of w-substituted poly(N-acryloyl-2-pyrrolidone)s. Polymer Chemistry (2015), 6, 5993-6000 PLUS JOURNAL COVER.
  129. Hernandez, E., Pawar, P., Keyvan, G., Wang, Y., Velez, N., Callegari, G., Drazer, G., Cuitino, A., Michniak-Kohn, B., Muzzio, F., Romanach, R.J. Prediction of dissolution profiles by non-destructive near infrared spectroscopy in tablets subjected to different levels of strain. Journal of Pharmaceutical and Biomedical Analysis, 2016, Jan 5th, 117, 568-576. PMID 26604167.
  130. Tsai, P., Zhang, Z., Roberts, K., Florek, C, Michniak-Kohn, B. Constructing human skin equivalents on porcine mesothelial acellular peritoneum extracellular matrix for in vitro irritation testing, Tissue Engineering Part A. (2016) Jan; 22(1-2): 111-22. (2015), Sept. 28 [Epub. ahead of print], PMID 26415037.
  131. Dorrani, M., Garbuzenko, O., Minko, T., Michniak-Kohn, B. Development of edge-activated liposomes for siRNA delivery to human basal epidermis for melanoma therapy. Journal of Controlled Release (2016), 228, 150-158. PMID 26965957.
  132. Adeleke, O., A., Monama, N.O., Tsai, P. Sithole, H.M., Michniak-Kohn, B. Application of a combination of atomistic molecular calculations and experimental investigations to the architecture, screening, optimization and characterization of pyrazinamide containing oral film formulations for tuberculosis management. Molecular Pharmaceutics, 2015, DOI: 10.1021/acs.molpharmaceut.5b00698. PMID 26650101.
  133. Silva, S. De, Michniak-Kohn, B. , Leonardi, G. R. An overview about oxidation in clinical practice of skin aging. Anais Brasileiros de Dermatologica (2017), May-June, 92 (3), 367-374. Doi: 10.1590/abd1806-4841.20175481.Review. PMID 29186250.
  134. Ramezanli, T., Zheng, Z., Michniak-Kohn, B. Development and characterization of polymeric nanoparticle-based formulation of adapalene for topical acne therapy. J. of Nanomedicine: Nanotechnology, Biology and Medicine (2016), doi: 10.1016/j.nano.2016.08.008. PMID 2756587.
  135. Ramezanli, T., Kilfoyle, B. Zhang, Z., Michniak-Kohn, B. Polymeric nanospheres for topical delivery of Vitamin D3. International Journal of Pharmaceutics, 2016, http://dx.doi.org/10.1016/j.ijpharm.2016.10.072 and (2017), 516, 196-203. PMID 27810351.
  136. Ameen, D. and Michniak-Kohn, B. Transdermal delivery of dimethyl fumarate for Alzheimer’s disease: Effect of penetration enhancers. International Journal of Pharmaceutics, 2017, August 30; 529 (1-2), 426-473; doi:10.1016/j.pharm.2017.07.031. Epub. 2017 July 12. PMID 28709939.
  137. Trehan, S., Michniak-Kohn, B., Beri, K. Plant stem cells in cosmetics: current trends and future directions. Future Science, 2017. Published on line https://doi.org/10.4155/fsoa-2017-0026 July 12th 2017 and Future Science, 2017, 3 (4), FSO226. PMID 29134115.
  138. Shah, P., Goodyear, B., Michniak-Kohn, B.B. A Review: Enhancement of solubility and oral bioavailability of poorly soluble drugs. Advance Pharmaceutical Journal, 2017, 2 (5), 161-173.
  139. Adeleke, O.A., Tsia, P-C., Karry, K., Monama, N.O., Hayeshi, R.K., Michniak-Kohn, B. Isoniazid-loaded orodispersible strips: Methodical design, optimization and in vitro-in silico characterization. International Journal of Pharmaceutics, 2018, 547, 347-359. https:/doi.org/10.1016/j/pharm.2018.06.004. PMID 29879506.
  140. Lin, H., Michniak-Kohn, B., Xia, Z., Xu, L., Kang, Q., Chen, C., Ma, S., Wu, Q. Transdermal delivery of compounds with different lipophilicity and molecular weight from W/O microemulsions analyzed by UPLC-Q-TOF/MS and LC-MS/MS. Current Drug Delivery, 2017, Dec 21; doi: 10:2174/1567201815666171221125411. [Epub ahead of print]. PMID 29268684.
  141. Haq, A. Dorrani, M., Goodyear, B., Joshi, V., Michniak-Kohn, B., Membrane Properties for Permeability Testing: Skin versus synthetic membranes, International Journal of Pharmaceutics, 2018, Jan 26 539 (1-2), 58-64. PMID 29366943.
  142.  Zhang, J., Michniak-Kohn, B.B. Investigation of microemulsion and microemulsion gel formulations for dermal delivery of clotrimazole. International Journal of Pharmaceutics, 2018, Jan 30; 536 (1), 345-352. https://doi.org/10.1016/j.ijpharm.2017.11.041. PMID 29170117.
  143. Ramezanli, T., Michniak-Kohn, B. Development and characterization of a topical gel formulation of adapalene-Tyrospheres and its clinical efficacy assessment. Molecular Pharmaceutics, 2018, July 31, doi:10.1021/acs.molpharmaceut.8b00318 (Epub ahead of print). Sept. 4; 15 (9):3813-3822. PMID 29996653.
  144. Haq, A., Goodyear, B. Ameen, D., Joshi, V., Michniak-Kohn, B. Strat-M synthetic membrane: Permeability comparison to human cadaver skin. Int. J. Pharmaceutics, 2018, Aug 25; 547 (1-2); 432-437 doi: 10.1016/j.ijpharm.2018.06.012. Epub. 2018 June 14. PMID 29890259.
  145. Ameen, D., Michniak-Kohn, B. Development and in vitro evaluation of pressure sensitive adhesive patch for the transdermal delivery of galantamine: Effect of penetration enhancers and crystallization inhibition. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 139, 262-271. Doi:10.1016/j.ejpb 2019.04.008. PMID 30981946.
  146. Haq, A., Michniak-Kohn, B. Effects of solvents and penetration enhancers on transdermal delivery of thymoquinone: permeability and skin deposition study. Drug Delivery, 2018, 25 (1), 1943-1949; doi:10:1080/10717544.2018.1523256. PMID 30463442.
  147. Haq, A., Chandler, M., Michniak-Kohn, B. Solubility-Physicochemical-Thermodynamic theory of penetration enhancer mechanism of action. Int. J. Pharm. (2019) Dec 18; 575:118920. Doi: 10:1016/j.ipharm.2019.118920. (Epub ahead of print). PMID 31863880 .
  148. Crosby, K., Rahman, A., Crawford, K.F., Shariat-Madar, Z., Michniak-Kohn, B., Tomalia, D.A., Rahman, A. A critical evaluation of the interaction of special proteins with human stratum corneum via terahertz scanning reflectometry and spectrometry. Precision Nanomedicine (2019), April; 2 (2), 253-26.
  149. Shultz, J., Leonardi, G.R., Michniak-Kohn, B. Evaluation of percutaneous absorption, cutaneous retention & cytotoxicity of topical formulations of ascorbyl glucoside containing kaolinite and smectite. Int. J. Pharm. (2020) (submitted).
  150. Carita, A., Santos, B.F., Schultz, J. D., Michniak-Kohn, B., Chorolli, M., Leonardi, G.R. Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability. (2019) Nanomedicine: Nanotechnology, Biology & Medicine October 30:102117. doi: 10.1016/j.nano.2019.102117. (epub ahead of print). PMID 31676375.
  151. Lin, H., Lin, L., Choi, Y. Michniak-Kohn, B. Development and evaluation of co-loaded berberine chloride and evodiamine ethosomes for treatment of melanoma. International J. Pharmaceutical Sciences (2020) May 15 581:119278 doi: https://doi.org/10.1016/j.ijpharm.2020.119278. PMID 32229284.
  152. Xu, Q., Jalilian, E., Fakhoury, J.W., Manwar, R., Michniak-Kohn, B., Elkin, K.B., Avanaki, K. Monitoring the topical delivery of ultrasmall gold nanoparticles using optical coherence tomography. Skin Research & Technology (2019) September 25. doi: 10.1111/srt.12789. PMID 31556193.
  153. Puri, V., Froelich, A., Pringle, S., Michniak-Kohn, B. Antifungal nanospheres: A novel drug delivery approach for treatment of onychomycosis guided by QbD. Pharmaceutics Special Edition “Quality by Design (QbD) for Topical Dermatological & Transdermal Product Development” Pharmaceutics (2020) (under review).
  154. Shah, P., Goodyear, B., Haq, A., Puri, V., Michniak-Kohn, B. Evaluations of Quality by Design (QbD) elements impact for developing niosomes as a promising topical drug delivery platform. Pharmaceutics Special Edition “Quality by Design (QbD) for Topical Dermatological & Transdermal Product Development” (2020) 12,246; doi:10.3390/pharmaceutics120302246. www.mdpi.com/journal/pharmaceutics.
  155. Zhang, Z.J., Froelich, A., Michniak-Kohn, B. Topical delivery of meloxicam using liposome and microemulsion formulation approaches. Pharmaceutics Special Edition “Nanosystems as Drug Delivery Carriers: From Nature to the Medication” (2020) 12,282; doi:10.3390/pharmaceutics120302282 www.mdpi.com/journal/pharmaceutics.
  156. Zhang, Z.J., Michniak-Kohn, B.B. Flavosomes, novel deformable liposomes for the co-delivery of anti-inflammatory compounds to skin. Int. J. Pharm. (2020) (under review).
  157. Ameen, D., Haq, A., Michniak-Kohn, B.B. Effects of pH and ionic form of nicotine on transdermal co-delivery with dimethyl fumarate across human skin in vitro. Int. J. Pharm. (2020) (under review).
  158. Anantaworasakul, P., Chaiyana, W., Michniak-Kohn, B.B., Rungseevijitprapa, W., Ampasavate, C. Enhanced transdermal delivery of concentrated capsaicin from chili extract-loaded lipid nanoparticles with reduced skin irritation. Pharmaceutics (2020) 12,463; doi:10.3390/pharmaceutics12050463 www.mdpi.com/journal/pharmaceutics.
  159. Jakubowska, E., Davin, S., Dumicic, A., Garbacz, G., Juppo, A., Michniak-Kohn, B., Rudzki, P. J., Smulek, W., Strachan, C., Syarkevych, O., Tajber, L., Lulek J. ORBIS (Open Research Biopharmaceutical Internships Support)- building bridges between academia and pharmaceutical industry to improve drug development. J. Med. Sci. (2020) (in press).
  160. Shah, P., Goodyear, B., Puri, V., Haq, A., Michniak-Kohn, B. A systematic Quality by Design (QbD) approach for optimization of niosome preparation using advanced statistical tool for the topical delivery of desoximethasone (2020) (in preparation).
  161. Haq, A., Kumar, S., Mao, Y., Berthiaume, F., Michniak-Kohn, B. Thymoquinone loaded polymeric films for the treatment of wound healing and bacterial skin infections. Biomaterials (2020) (submitted).
  162. Osmałek T., Froelich A., Gadziński P., Michniak-Kohn B. Topical delivery of methylene blue, rose bengal and protoporphyrin IX for the photodynamic treatment of skin cancers (2020) (in preparation).