Parinbhai Shah (Ph.D. Student)
Research Interests:
- Design and evaluate vesicle based topical drug delivery using quality by design (QbD) approach.
- Design, development, characterization, and evaluation of dermal formulations.
- Design of experiment based on QbD and drug formulation development of ANDAs and 505(b)(2).
Current Industrial Position:
- Principal Formulation Scientist – Specialty generic product, Akorn Pharmaceuticals, Cranbury, NJ, USA.
Previous Industrial Position:
- Senior Formulation Scientist – Specialty generic product, Novel Labs, Somerset, NJ, USA.
- Formulation Scientist – MEND labs, Boston, NJ, USA.
- Research Scientist – Long Island University, Brooklyn, NY, USA.
- Trainee Intern, Apex Formulations PVT. LTD., Gujarat, India.
Regulatory Affairs officer for US-FDA, Claris Lifesciences Ltd., Gujarat, India.
Current Research:
Topic: “Develop and evaluation desoximetasone loaded niosomes for topical drug delivery using quality by design (QbD) approach.”
- Develop a niosomal vesicle based delivery system to deliver a variety of hydrophobic/hydrophilic drugs with improved bioavailability and better stability.
- Develop drug loaded niosome containing topical gel for the treatment of various skin conditions such as psoriasis, eczema, itching, redness, etc. by sustaining release drug delivery.
- An advanced way to deliver target specific drugs by improving drug availability at the site of action.
- Controlled release drug delivery helps to release drug longer period, which helps to reduce drug application frequency or reduce drug concentration in the formulation.
Publications:
- “Evaluation of Quality by Design (QbD) Elements Impact for Developing Niosomes as a Promising Topical Drug Delivery Platform. (Shah, P.; Goodyear, B.; Haq, A.; Puri, V.; Michniak-Kohn, B. Pharmaceutics 2020, 12, 246; https://doi.org/10.3390/pharmaceutics12030246)
- “Quality by Design: A Systematic Approach using an Advanced Statistical Tool to Optimization of Niosomes Preparation for the Topical Delivery (Shah, P.; Goodyear, B.; Haq, A.; Puri, V.; Michniak-Kohn, B.) (Under review)
- “A review: Enhancement of solubility and oral bioavailability of poorly soluble drugs” (Shah, P.; Goodyear, B.; Michniak-Kohn, B., Advance Pharmaceutical journal 2017; 2(5):161-173)
Awards, Honors, and Recognition:
- Member of “Beta Theta Chapter of the Rho Chi, the Academic Honor Society in Pharmacy with Rho Chi Scholar Award.” (2009).
- Member of the prestigious elite group “Who’s Who Among Students in American Universities and Colleges with Who’s Who Among Students Award.” (2010).
- Consecutively awarded with a student of Long Island University’s best class of 2009-10 & 2010-11.
Personal Interests:
Ophthalmic Product, Dermal Formulation, Specialty Product, Formulation Development, Innovative Research, QbD, Targeted drug delivery, Science, NDA, ANDA, 505(b)(2).