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Cerda, Debbie: In Silico Analyses Of Small Proteins In Escherichia Coli

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Title: In Silico Analyses of Small Proteins in Escherichia Coli

Name: Debbie Cerda

Major: Genetics

School affiliation: School of Arts and Sciences

Programs: Division of Life Sciences Summer Undergraduate Research Fellowship (DLS-SURF)

Other contributors: Debbie Cerda, McKenzie Burge and Srujana S. Yadavalli

Abstract: Creation of a curated database of all novel small proteins in Escherichia coli K12 MG1655 as of 2019. Database consists of a comprehensive list consisting of small proteins and the genes that encode them, as well as information that bioinformatically characterizes their functions, structures, protein – protein interactions, gene neighborhoods, localization predictions, taxonomy and antimicrobial peptide activity predictions. The criteria for entry is a protein that is less than 100 amino acids in length, and discovered within the year 2008 to present. The thought is that uncovering the identities and functions of small proteins will be beneficial in expanding the amount of information known about important signaling pathways not only in bacteria, but all organisms.