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Publications

Byrne A, Diener C, Brown BP, Maust BS, Feng C, Alinde BL, Gibbons SM, Koch M, Gray CM, Jaspan HB, Nyangahu DD. Neonates exposed to HIV but uninfected exhibit an altered gut microbiota and inflammation associated with impaired breast milk antibody function. Microbiome. 2024 Dec 20;12(1):261. doi: 10.1186/s40168-024-01973-z. PubMed PMID: 39707483; PubMed Central PMCID: PMC11662858.

Nyangahu DD, Happel AU, Wendoh J, Kiravu A, Wang Y, Feng C, Plumlee C, Cohen S, Brown BP, Djukovic D, Ganief T, Gasper M, Raftery D, Blackburn JM, Allbritton NL, Gray CM, Paik J, Urdahl KB, Jaspan HB. Bifidobacterium infantis associates with T cell immunity in human infants and is sufficient to enhance antigen-specific T cells in mice. Sci Adv. 2023 Dec 8;9(49):eade1370. doi: 10.1126/sciadv.ade1370. Epub 2023 Dec 8. PubMed PMID: 38064556; PubMed Central PMCID: PMC10708209.

Happel AU, Rametse L, Perumaul B, Diener C, Gibbons SM, Nyangahu DD, Donald KA, Gray C, Jaspan HB. Bifidobacterium infantis supplementation versus placebo in early life to improve immunity in infants exposed to HIV: a protocol for a randomized trial. BMC Complement Med Ther. 2023 Oct 18;23(1):367. doi: 10.1186/s12906-023-04208-0. PubMed PMID: 37853370; PubMed Central PMCID: PMC10583347.

Brown BP, Feng C, Tanko RF, Jaumdally SZ, Bunjun R, Dabee S, Happel AU, Gasper M, Nyangahu DD, Onono M, Nair G, Palanee-Phillips T, Scoville CW, Heller K, Baeten JM, Bosinger SE, Burgener A, Passmore JS, Heffron R, Jaspan HB. Copper intrauterine device increases vaginal concentrations of inflammatory anaerobes and depletes lactobacilli compared to hormonal options in a randomized trial. Nat Commun. 2023 Jan 30;14(1):499. doi: 10.1038/s41467-023-36002-4. PubMed PMID: 36717556; PubMed Central PMCID: PMC9886933.
Nyangahu DD, Plumlee CR, Brown BP, Feng C, Havyarimana E, Cohen SB, Urdahl KB, Jaspan HB. Antibiotic Treatment during Gestation Enhances Susceptibility to Mycobacterium tuberculosis in Offspring. Microbiol Spectr. 2022 Dec 21;10(6):e0249122. doi: 10.1128/spectrum.02491-22. Epub 2022 Oct 31. PubMed PMID: 36314979; PubMed Central PMCID: PMC9769670.
Brown BP, Chopera D, Havyarimana E, Wendoh J, Jaumdally S, Nyangahu DD, Gray CM, Martin DP, Varsani A, Jaspan HB. crAssphage genomes identified in fecal samples of an adult and infants with evidence of positive genomic selective pressure within tail protein genes. Virus Res. 2021 Jan 15;292:198219. doi: 10.1016/j.virusres.2020.198219. Epub 2020 Nov 1. PubMed PMID: 33137401; PubMed Central PMCID: PMC7778472.
Nyangahu DD, Darby M, Havyarimana E, Brown BP, Horsnell W, Jaspan HB. Preconception helminth infection alters offspring microbiota and immune subsets in a mouse model. Parasite Immunol. 2020 Sep;42(9):e12721. doi: 10.1111/pim.12721. Epub 2020 May 3. PubMed PMID: 32277499; PubMed Central PMCID: PMC7423732.
Nyangahu DD, Jaspan HB. Influence of maternal microbiota during pregnancy on infant immunity. Clin Exp Immunol. 2019 Oct;198(1):47-56. doi: 10.1111/cei.13331. Epub 2019 Jun 21. Review. PubMed PMID: 31121057; PubMed Central PMCID: PMC6718277.
Darby MG, Chetty A, Mrjden D, Rolot M, Smith K, Mackowiak C, Sedda D, Nyangahu D, Jaspan H, Toellner KM, Waisman A, Quesniaux V, Ryffel B, Cunningham AF, Dewals BG, Brombacher F, Horsnell WGC. Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring. Sci Adv. 2019 May;5(5):eaav3058. doi: 10.1126/sciadv.aav3058. eCollection 2019 May. PubMed PMID: 31236458; PubMed Central PMCID: PMC6587632.
Nyangahu DD, Lennard KS, Brown BP, Darby MG, Wendoh JM, Havyarimana E, Smith P, Butcher J, Stintzi A, Mulder N, Horsnell W, Jaspan HB. Disruption of maternal gut microbiota during gestation alters offspring microbiota and immunity. Microbiome. 2018 Jul 7;6(1):124. doi: 10.1186/s40168-018-0511-7. PubMed PMID: 29981583; PubMed Central PMCID: PMC6035804.