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Publications

  1. Saleena Alikunju, Elena Severinova, Zhi Yang, Andreas Ivessa, Danish Sayed. Acute NelfA knockdown restricts compensatory gene expression and precipitates ventricular dysfunction during cardiac hypertrophy.Journal of Molecular and Cellular Cardiology (JMCC), 2020 May;142:93-104. PMID: 32278832. 
  2. Liu C, Ruan H, Himmati F, Zhao M, Chen C, Makar M, Chen I, Sallam K, Mocarski E, Sayed Danish, Sayed Nazish. Hif1a regulates early metabolic changes due to activation of innate immunity in nuclear reprogramming. Stem Cell Reports. 2020 Feb 11;14(2):192-2020
  3. Elena Severinova, Saleena Alikunju, Wei Deng, Puneet Dhawan, Nazish Sayed and Danish Sayed.A Glucocorticoid receptor –binding and –transcriptome signature in cardiomyocytes. Journal of American Heart Association (JAHA), 2019 Mar 19;8(6):e011484 PMID: 30866692.
  4. Choi S, Pfleger J, Jeon Y, Yang Z, He M, Sayed Danish, Astrof S, Abdellatif M. Oxoglutarate dehydrogenase and acetyl-CoA acyltransferase 2 selectively associate with H2A.Z-occupied promoters and are required for histone modifications. BBA-Gene regulatory Mechanisms. 2019 Oct;1862(10):194436
  5. Bhat S, Chin A, Shirakabe A, Ikeda Y, Ikeda S, Zhai P, Hsu C,Sayed Danish, Abdellatif M, Kevin J, Tang F, Tian Y, Babu G, Ralda G, Warren J, Cho J, Sadoshima J, Oka S. Recruitment of RNA pol II to metabolic gene promoters is inhibited in the failing hearts possible through PGC-1alpha dysregulation. Circulation heart failure, 2019 Mar; 12(3):e005529
  6. Shin H, He M, Yang Z, Pfleger J, Sayed Danishand Abdellatif M. Transcriptional regulation mediated by H2A.Z via ANP32e-dependnt inhibition of protein phosphatase 2A.Biochim Biophys Acta. 2018 May; 1861(5):481-496.
  7. Minzhen He, Zhi Yang, Abdellatif Maha and Danish Sayed. Ras GTPase-activating Protein SH3 Domain Binding Protein (G3BP1) regulates posttranscriptionally regulates pre-miR-1 processing and controls mature miR-1 levels in heart. PlosOne. December 16;10(12):e0145112. 2015. PMID:26675618.
  8. Danish Sayed*, Minzhen He, Zhi Yang, Jessica Pfleger and Maha Abdellatif*. Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription. *Co-corresponding. Circulation Heart Failure. January;8(1):138-48 2015. PMID: 25398966.
  9. Del Re DP, Nakano N, Sciarretta S, Zhai P, Park J, Sayed Danish, Shirakabe A, Matsushima S, Park Y, Tian B, Abdellatif M, Sadohima J. miR-206 Mediates YAP-Induced Cardiac Hypertrophy and Survival. Circulation Research. October 23; 117(10):891-904. 2015
  10. Danish Sayed, Minzhen He, Zhi Yang, Lin Lin, Maha Abdellatif. Transcriptional regulation patterns revealed by high-resolution chromatin immunoprecipitation during cardiac hypertrophy. Journal of Biological Chemistry. January 25, 288: 2485-2500; 2013. Impact factor 5.328
  11. Minghue Han, Zhi Yang, Danish Sayed, Minzhen He, Shumin Gao, Lin Lin, Seong Hun Yoon, Maha Abdellatif. GATA4 Expression is Primarily Regulated via a miR-26-Dependent Posttranscriptional Mechanism During Cardiac Hypertrophy.Cardiovascular Research, March 15; 93(4): 645-54, 2012
  12. Danish Sayed and Maha Abdellatif. MicroRNAs in Development and Disease. Physiological Reviews. July; 91, 2011.
  13. Danish Sayedand Maha Abdellatif. AKT-ing via microRNA.Cell Cycle. August 15; 9(16).2010.
  14. Danish Sayed, Minzhen He, Zhi Yang, Shweta Rane, Maha Abdellatif. MicroRNA-21 is downstream effector of AKT and mediates its anti-apoptotic effects via suppression of Fas Ligand.Journal of Biological Chemistry (JBC). June 25; 285: 20281-20290, 2010.
  15. Shweta Rane, Minzhen He, Danish Sayed, Lin Yan, Dorothy Vatner, Maha Abdellatif. An antagonism between the AKT and b-adrenergic signaling pathways mediated through their reciprocal effects on miR-199a-5p. Cellular Signalling. July; 22(7): 1054-62. 2010.
  16. Shweta Rane, Minzhen He, Danish Sayed, Himanshu Vashistha, Ashwani Malhotra, Junichi Sadoshima, Dorothy Vatner, Stephen Vatner, Maha Abdellatif. Downregulation of miR-199a derepresses hypoxia-inducible factor-1aand Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.Circulation Research.April 10; 104(7): 879-86. 2009.
  17. Danish Sayed, Shweta Rane and Maha Abdellatif. MicroRNAs Challenge the Status Quo of Therapeutic Targeting.Journal of Cardiovascular Translational Research. Mar; 2(1): 100-7, 2009
  18. Danish Sayed, Shweta Rane, Jacqueline Lypowy, Minzhen He, Ieng-Yi Chen, Himanshu Vashistha, Lin Yan, Ashwani Malhotra, Dorothy Vatner and Maha Abdellatif. MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths.Molecular Biology of the Cell. Aug; Vol 19: 3272-3282.2008.
  19. Rane Shweta, Danish Sayed, Abdellatif Maha. MicroRNA with a MacroFunction. Cell Cycle 6(15):1850-1855, 2007.
  20. Danish Sayed, Chull Hong, Ieng-Yi Chen, JacquelineLypowy, Maha Abdellatif. MicroRNA play an essential role in the development of cardiac hypertrophy.Circulation Research.Feb 16; 100(3): 416-24. 2007.
  21. Chen IY, Lupowy J, Pain J, Danish Sayed, Grinberg S, Alcendor R, Sadoshima J, Abdellatif M. Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2alpha. Journal ofBiological Chemistry.Jul 14; 281(28): 19369-77. 2006.