Publications

Glytsou, C.^#, *, Chen, X.*, Zacharioudakis, E.*, Al-Santli, W., Zhou, H., Sun, Z., Zal, T., Zal, M.A., Ishizawa, J., Tibes, R., Tsirigos, A., Andreeff. M., Gavathiotis, E.^#, Aifantis, I^#. (2023). Mitophagy promotes resistance to BH3 mimetics in acute myeloid leukemia. Cancer Discovery doi:10.1158/2159-8290.CD-22-0601.

Chen, X.*, Glytsou, C.*, Zhou, H., Narang, S., Reyna, D.E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y.S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R., and Aifantis, I. (2019). Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment. Cancer Discov 9, 890-909. doi: 10.1158/2159-8290.CD-19-0117. PMC ID: PPMC6606342

Commentary – Savona MR, Rathmell JC. (2019). Mitochondrial Homeostasis in AML and Gasping for Response in Resistance to BCL2 Blockade. Cancer Discov 9, 831-33. doi:10.1158/2159-8290.CD-19-0510.

Thandapani, P., Kloetgen, A.*, Witkowski, M.T.*, Glytsou, C.*, Lee, A.K., Wang, E., Wang, J., LeBoeuf, S.E., Avrampou, K., Papagiannakopoulos, T., Tsirigos, A., and Aifantis, I. (2021). Valine tRNA levels and availability regulate complex I assembly in leukaemia. Nature. doi: 10.1038/s41586-021-04244-1

DiNardo, C.D., Tiong, I.S., Quaglieri, A., MacRaild, S., Loghavi, S., Brown, F.C., Thijssen, R., Pomilio, G., Ivey, A., Salmon, J.M., Glytsou, C., Fleming, S.A., Zhang, Q., Ma, H., Patel, K.P., Kornblau, S.M., Xu, Z., Chua, C.C., Chen, X., Blombery, P., Flensburg, C., Cummings, N., Aifantis, I., Kantarjian, H., Huang, D.C.S., Roberts, A.W., Majewski, I.J., Konopleva, M., and Wei, A.H. (2020). Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML. Blood 135, 791-803. doi: 10.1182/blood.2019003988. PMC ID: PPMC7068032

Giacomello, M., Pyakurel, A., Glytsou, C., and Scorrano, L. (2020). The cell biology of mitochondrial membrane dynamics. Nat Rev Mol Cell Biol 21, 204-224. doi: 10.1038/s41580-020-0210-7

Glytsou, C., Calvo, E., Cogliati, S., Mehrotra, A., Anastasia, I., Rigoni, G., Raimondi, A., Shintani, N., Loureiro, M., Vazquez, J., Pellegrini, L., Enriquez, J.A., Scorrano, L., and Soriano, M.E. (2016). Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control. Cell Rep 17, 3024-3034. doi: 10.1016/j.celrep.2016.11.049. PMC ID: PPMC5186903

Quintana-Cabrera, R., Quirin, C., Glytsou, C., Corrado, M., Urbani, A., Pellattiero, A., Calvo, E., Vazquez, J., Enriquez, J.A., Gerle, C., Soriano, M.E., Bernardi, P., and Scorrano, L. (2018). The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function. Nat Commun 9, 3399. doi: 10.1038/s41467-018-05655-x. PMC ID: PPMC6109181

Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N.N., Glytsou, C., Pateras, I.S., Swain, U., Souliotis, V.L., Georgakilas, A.G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sorensen, C.S., Bartek, J., and Gorgoulis, V.G. (2018). Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability. Genome Biol 19, 37. doi: 10.1186/s13059-018-1401-9. PMC ID: PPMC5857109

Aivaliotis, I.L., Pateras, I.S., Papaioannou, M., Glytsou, C., Kontzoglou, K., Johnson, E.O., and Zoumpourlis, V. (2012). How do cytokines trigger genomic instability? J Biomed Biotechnol 2012, 536761. doi: 10.1155/2012/536761. PMC ID: PPMC3382994