Nicole Vega-Cotto

Publications:

Moloughney, J.G., Vega-Cotto, N.M., Liu, S., Patel, C., Kim, P.K., Wu, C., Albaciete, D., Magaway, C., Chang, A., Rajput, S., Su, X., Werlen, G., and Jacinto, E. mTORC2 modulates the amplitude and duration of GFAT1 Ser243 phosphorylation to maintain flux through the hexosamine pathway during starvation.  J. Biol Chem. 2018, 293(42): 16464-16478, PMID 30201609

 

Moloughney, J.G.*, Kim, P.K.*, Vega-Cotto, N.M.*, Wu, C., Zhang, S., Adlam, M., Lynch, T., Chou, P.C., Rabinowitz, J.D., Werlen, G. and Jacinto, E. mTORC2 responds to glutamine catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1. Molecular Cell 2016, 63, 811-826. PMID:27570073

 

Chi, O.Z., Barsoum, S., Vega-Cotto, N.M., Jacinto, E., Liu X., Mellender, S.J., and Weiss, H.R. Effects of rapamycin on cerebral oxygen supply and consumption during reperfusion after cerebral ischemia, Neuroscience 2016 316:321-7. PMID 26742793

 

Kim, S.J*., DeStefano, M.A.*, Oh, W.J., Wu, C., Vega-Cotto, N.M., Finlan, M., Liu, D., Su, B., and Jacinto, E. mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase Fbw8.  Molecular Cell 2012; 48, 875-887.  PMID: 23142081