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Selected Publications

  1. Porreca I, Blassberg R, Harbottle J, Joubert B, Mielczarek O, Stombaugh J, Hemphill K, Sumner J, Pazeraitis D, Touza JL, Francescatto M, Firth M, Selmi T, Collantes JC, Strezoska Z, Taylor B, Jin S, Wiggins CM, van Brabant Smith A, Lambourne JJ. An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation. Mol Ther. 2024 Aug 7;32(8):2692-2710. doi: 10.1016/j.ymthe.2024.06.033. Epub 2024 Jun 26. PMID: 38937969.
  2. da Silva-Diz V, Cao B, Lancho O, Chiles E, Alasadi A, Aleksandrova M, Luo S, Singh A, Tao H, Augeri DJ, Minuzzo S, Indraccolo S, Khiabanian H, Su X, Jin S,* Herranz D. A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia. Blood. 2021 Apr 19; PubMed PMID: 33876224. (*Jin. S. is a co-corresponding author)
  3. Alasadi, A., Cao, B., Guo, J., Tao, H., Collantes, J., Tan, V., Su, X., Augeri, D. and Jin, S. Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models. Oncogene, 2021;40(12):2285-2295
  4. Collantes, J.C., Tan, V.M., Xu, H., Ruiz-Urigüen, M., Alasadi, A., Guo, J., Tao, H., Su, C., Tyc, K.M., Selmi, T. and Lambourne, J.J., 2021. Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System. The CRISPR journal, 4(1), 58-68.
  5. Alasadi, A., Chen, M., Swapna, G.V.T., Tao, H., Guo, J., Collantes, J., Fadhil, N., Montelione, G.T. and Jin, S., 2018. Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer. Cell death & disease, 9(2),1-14.
  6. Guo, J., Cao, Y., Ho, C.T., Jin, S. and Huang, Q., 2017. Aged citrus peel (chenpi) extract reduces lipogenesis in differentiating 3T3-L1 adipocytes. Journal of Functional Foods, 34, pp.297-303.
  7. Tao, H., Zhang, Y., Zeng, X., Shulman, G.I. and Jin, S., 2014. Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice. Nature medicine, 20(11), pp.1263-1269.
  8. Goldman, S.J., Chen, E., Taylor, R., Zhang, S., Petrosky, W., Reiss, M. and Jin, S., 2011. Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice. PloS one, 6(3), p.e18269.
  9. Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc. Natl. Acad. Sci. (47):19860-5. PubMed PMID: 19910529; PubMed Central PMCID: PMC2785257.
  10. Karantza-Wadsworth, V., Patel, S., Kravchuk, O., Chen, G., Mathew, R., Jin, S. and White, E., 2007. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes & development, 21(13), pp.1621-1635.
  11. Mathew, R., Kongara, S., Beaudoin, B., Karp, C.M., Bray, K., Degenhardt, K., Chen, G., Jin, S. and White, E., 2007. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes & development, 21(11), pp.1367-1381.
  12. Levine, A.J., Feng, Z., Mak, T.W., You, H. and Jin, S., 2006. Coordination and communication between the p53 and IGF-1–AKT–TOR signal transduction pathways. Genes & development, 20(3), pp.267-275.
  13. Feng, Z., Zhang, H., Levine, A.J. and Jin, S., 2005. The coordinate regulation of the p53 and mTOR pathways in cells. Proc. Natl. Acad. Sci., 102(23), pp.8204-8209.
  14. Yue, Z., Jin, S., Yang, C., Levine, A.J. and Heintz, N., 2003. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci., 100(25), pp.15077-15082.
  15. Jin, S., Kalkum, M., Overholtzer, M., Stoffel, A., Chait, B.T. and Levine, A.J., 2003. CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes & development, 17(3), pp.359-367.
  16. Jin, S., Martinek, S., Joo, W.S., Wortman, J.R., Mirkovic, N., Sali, A., Yandell, M.D., Pavletich, N.P., Young, M.W. and Levine, A.J., 2000. Identification and characterization of a p53 homologue in Drosophila melanogaster. Proc. Natl. Acad. Sci., 97(13), pp.7301-7306.