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Selected Publications

  1. da Silva-Diz V, Cao B, Lancho O, Chiles E, Alasadi A, Aleksandrova M, Luo S, Singh A, Tao H, Augeri DJ, Minuzzo S, Indraccolo S, Khiabanian H, Su X, Jin S,* Herranz D. A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia. Blood. 2021 Apr 19; PubMed PMID: 33876224. (*Jin. S. is a co-corresponding author)
  2. Alasadi, A., Cao, B., Guo, J., Tao, H., Collantes, J., Tan, V., Su, X., Augeri, D. and Jin, S. Mitochondrial uncoupler MB1-47 is efficacious in treating hepatic metastasis of pancreatic cancer in murine tumor transplantation models. Oncogene, 2021;40(12):2285-2295
  3. Collantes, J.C., Tan, V.M., Xu, H., Ruiz-Urigüen, M., Alasadi, A., Guo, J., Tao, H., Su, C., Tyc, K.M., Selmi, T. and Lambourne, J.J., 2021. Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System. The CRISPR journal, 4(1), 58-68.
  4. Alasadi, A., Chen, M., Swapna, G.V.T., Tao, H., Guo, J., Collantes, J., Fadhil, N., Montelione, G.T. and Jin, S., 2018. Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer. Cell death & disease, 9(2),1-14.
  5. Guo, J., Cao, Y., Ho, C.T., Jin, S. and Huang, Q., 2017. Aged citrus peel (chenpi) extract reduces lipogenesis in differentiating 3T3-L1 adipocytes. Journal of Functional Foods, 34, pp.297-303.
  6. Tao, H., Zhang, Y., Zeng, X., Shulman, G.I. and Jin, S., 2014. Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice. Nature medicine, 20(11), pp.1263-1269.
  7. Goldman, S.J., Chen, E., Taylor, R., Zhang, S., Petrosky, W., Reiss, M. and Jin, S., 2011. Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice. PloS one, 6(3), p.e18269.
  8. Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc. Natl. Acad. Sci. (47):19860-5. PubMed PMID: 19910529; PubMed Central PMCID: PMC2785257.
  9. Karantza-Wadsworth, V., Patel, S., Kravchuk, O., Chen, G., Mathew, R., Jin, S. and White, E., 2007. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes & development, 21(13), pp.1621-1635.
  10. Mathew, R., Kongara, S., Beaudoin, B., Karp, C.M., Bray, K., Degenhardt, K., Chen, G., Jin, S. and White, E., 2007. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes & development, 21(11), pp.1367-1381.
  11. Levine, A.J., Feng, Z., Mak, T.W., You, H. and Jin, S., 2006. Coordination and communication between the p53 and IGF-1–AKT–TOR signal transduction pathways. Genes & development, 20(3), pp.267-275.
  12. Feng, Z., Zhang, H., Levine, A.J. and Jin, S., 2005. The coordinate regulation of the p53 and mTOR pathways in cells. Proc. Natl. Acad. Sci., 102(23), pp.8204-8209.
  13. Yue, Z., Jin, S., Yang, C., Levine, A.J. and Heintz, N., 2003. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci., 100(25), pp.15077-15082.
  14. Jin, S., Kalkum, M., Overholtzer, M., Stoffel, A., Chait, B.T. and Levine, A.J., 2003. CIAP1 and the serine protease HTRA2 are involved in a novel p53-dependent apoptosis pathway in mammals. Genes & development, 17(3), pp.359-367.
  15. Jin, S., Martinek, S., Joo, W.S., Wortman, J.R., Mirkovic, N., Sali, A., Yandell, M.D., Pavletich, N.P., Young, M.W. and Levine, A.J., 2000. Identification and characterization of a p53 homologue in Drosophila melanogaster. Proc. Natl. Acad. Sci., 97(13), pp.7301-7306.