Image Galery - Astrof Lab

People’s Choice Winner-American Society for Matrix Biology Image Competition 2022. ***Field of Roses – The intricate Fibronectin Matrix. Image Credit: Brianna Alexander.***

Fibronectin matrix: Sudipto Munshi

Scanning EM of an early mouse embryo: Sophie Astrof

Heart and the aortic arch arteries, imaged by micro computed tomography: AnnJosette Ramirez

E10.5 embryo heart and vasculature:AnnJosette Ramirez

Mef2C-AHF-Cre lineage and VEGFR2-stained vasculature

E8.0 mouse embryo: Michael Warkala

Pharyngeal arch arteries: AnnJosette Ramirez

Delicate arch

Thick fibronectin fibril at 23 nm resolution

Fibronectin fibril visualized with a polyclonal antibody to fibronectin and imaged using direct STORM. Scale bar is 100 nm.

Scanning EM of hearts: Sophie Astrof

Pharyngeal arch arteries in E10.5 mouse embryo. Sagittal view of three-dimensional maximum intensity projection of whole-mount immunofluorescence staining shows the heart connecting with the dorsal aorta through three pharyngeal arch arteries. Endothelial cell nuclei in the pharyngeal arch arteries and the dorsal aorta are marked in pink by highlighting the expression of ERG. Endothelial cell membranes are marked by the expression of Vascular Endothelial Growth Factor 2 (VEGFR2): red (heart), white (pharyngeal arch arteries and dorsal aorta), and blue (the rest of the embryo). Photo Credit: Michael Warkala

The heart from 9.5-day-old mouse embryo was surfaced to highlight the distal outflow tract (orange), proximal outflow tract and the right ventricle (maroon), the left ventricle and atrio-ventricular canal (blue), and atria in pink. Photo Credit: Michael Schonning

E9.5 Vasculature. Photo Credit: Sophie Astrof

Fibronectin matrix formation in mouse embryo fibroblasts. Arrows point to fibril initiation sites. Photo Credit: Darshika Tomer

Migration of Mesp1-lineage mesoderm in E7.5 mouse embryo. Arrows point to migrating mesodermal cells. Photo Credit: Cecilia Arriagada