Research
We are currently recruiting for the following studies. Please contact the specific coordinator listed or our central research email at memory411@rutgers.edu
CSF, MRI, and PET biomarker of inflammation in Alzheimer’s disease
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- The goal of the study is to better understand how inflammatory changes in the brain can be detected in the spinal fluid, MRI, and PET scan
- We are looking for people with mild cognitive impairment (MCI) or mild dementia due to Alzheimer’s disease
- Contact: Memory411@rutgers.edu or Victor Sotelo
Beyond haploinsufficiency: Biomarkers in frontotemporal lobar degeneration (FTLD) due to progranulin (GRN) mutations
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- The goal of the study is to determine if some people with mutated GRN genes create abnormal proteins in their spinal fluid and blood
- We are looking for people from families with known GRN mutations or inherited forms of frontotemporal dementia/primary progressive aphasia
- Contact: Memory411@rutgers.edu or Victor Sotelo
Brain fog in long COVID
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- The goal of this study is to describe inflammatory changes in the spinal fluid and blood of people who develop thinking and memory issues (“brain fog”) after recovering from COVID-19
- We are looking for people who had mild to moderate COVID-19 (never intubated) who feel their memory and thinking is worse than before the infection
- Contact: Memory411@rutgers.edu or Kristen Briney
Rutgers-Stanford Chinese Older Adult Study (COAST)
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- The goal of this study is to compare performance on Mandarin- and English cognitive tests among bilingual older adults, correlate performance on Mandarin testing with brain structure/function, and determine diagnostic thresholds for cognitive impairment among Mandarin speakers
- Contact: Mei-ling Li or Guibin Su
Memory and Aging in South Asian Americans
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- There are two on-going studies focusing on the aging brain in older South Asians
- South Asian Aging Brain (SAAB)
- Studying Attitudes towards MRI Research in Older South Asians (SAMOSA)
- Contact: Shromona Sarkar
- There are two on-going studies focusing on the aging brain in older South Asians
E2: Sex Hormones & Alzheimer’s Disease Prevention Study
The purpose of the E2: Sex Hormones & Alzheimer’s Disease Prevention Study is to better understand how fluctuations in sex hormones (such as estrogen) during middle age influence sleep, memory, and future Alzheimer’s Disease (AD) risks in Black/African American and White adults.
This may be especially important in people with a family history of Alzheimer’s disease in their parents or grandparents.
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- We are looking to collect information from participants with diverse backgrounds, which include:
- Black/African Americans and White (non-Hispanic) Americans between 45 and 85 years of age
- Normal memory and thinking, or a diagnosis of mild cognitive impairment (MCI)
- Contact: Call (551)-2762474 or Memory411@rutgers.edu.
- We are looking to collect information from participants with diverse backgrounds, which include:
Annals of Neurology
Interleukin 9 alterations linked to Alzheimer disease in African Americans
Whitney Wharton, Alexander L Kollhoff, Umesh Gangishetti, Danielle D Verble, Samsara Upadhya, Henrik Zetterberg, Veena Kumar, Kelly D Watts, Andrea J Kippels, Marla Gearing, J Christina Howell, Monica W Parker, William T Hu
Emerging Infectious Diseases
Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020
Karima Benameur, Ankita Agarwal, Sara C Auld, Matthew P. Butters, Andrew S Webster, Tugba Ozturk, J Christina Howell, Leda C Bassit, Alvaro Velasquez, Raymond F Schinazi, Mark E Mullins, William T Hu
Alzheimer's and Dementia
Perspective on the “African American participation in Alzheimer disease research: Effective strategies” workshop, 2018
Andrea Denny, Marissa Streitz, Kristin Stock, Joyce E Balls-Berry, Lisa L Barnes, Goldie S Byrd, Raina Croff, Sujuan Gao, Crystal M Glover, Hugh C Hendrie, William T Hu, Jennifer J Manly, Krista L Moulder, Susan Stark, Stephen B Thomas, Rachel Whitmer, Roger Wong, John C Morris, Jennifer H Lingler