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Publications in the past 10 years:

Zanin, J.P., M.A. Pandya, D. Espinoza, W.J. Friedman, and M.W. Shiflett, Excess cerebellar granule neurons induced by the absence of p75NTR during development elicit social behavior deficits in mice, Frontiers in Molecular Neuroscience, Volume 16, |, 2023

Subhashini Joshi, Michelle J. Frondelli, Juan P. Zanin, Steven W. Levison and Wilma J. Friedman, Oligodendrocyte progenitor development from the postnatal rat subventricular zone is regulated by the p75 neurotrophin receptor, Glia,, 2023

Zanin, J.P. and W.J. Friedman, p75NTR prevents the onset of cerebellar granule cell migration via RhoA activation, eLife,, 2022

Montroull, L.E., D. Rothbard, H.D. Kanal, V. D’Mello, V. Dodson, C.M. Troy, J.P. Zanin, S.W. Levison, and W.J. Friedman, Pro-Neurotrophins induce apoptotic neuronal death after controlled cortical impact injury in adult mice, ASN Neuro, 12:1-13;, 2020

Zanin, J.P.*, L.E. Montroull*, M. Volosin, and W.J. Friedman, p75NTR modulates TrkB trafficking and signaling in response to BDNF treatment in hippocampal neurons, Frontiers in Cellular Neuroscience,, 2019

Zanin, J.P., J. Verpeut, Li, Y., Shiflett, M.W., S.-S. Wang, Santhakumar, V., and W.J. Friedman, The p75NTR influences cerebellar circuit development and adult behavior via regulation of cell cycle duration of granule cell progenitors, J. Neurosci. 39 (46) 9119-9129; DOI:, 2019, Cover Article

Saadipour, K., A. Tiberi, S. Lomardo, L. Montroull, N. Manucat, J. LaFrancois, M. Cammer, P. Mathews, H. Scharfman, F.-F. Liao, W. Friedman, X.-F. Zhou, G. Tesco, and M. Chao, Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor, Molecular and Cellular Neuroscience, 99,, 2019

Cragnolini, A.B., G. Montenegro, W.J. Friedman, and D.H. Mascó, Brain-region specific responses of astrocytes to an in vitro injury and neurotrophins, Molecular and Cellular Neuroscience, 88:240-248, doi: 10.1016/j.mcn.2018.02.007, 2018

Greenwood, S.G. L. Montroull, M. Volosin, H. E. Scharfman, K.K.Teng, M. Light, R. Torkin, F. Maxfield, B.L. Hempstead, and W.J. Friedman, A novel neuroprotective mechanism for lithium that prevents association of the p75NTR-sortilin receptor complex and attenuates proNGF-induced neuronal death in vitro and in vivo, eNeuro, 5 (1) DOI: 2017

Zanin, J.P., E. Abercrombie, and W.J. Friedman, Proneurotrophin-3 promotes cell cycle withdrawal of developing cerebellar granule cell progenitors via the p75 neurotrophin receptor, eLife, DOI: 10.7554/eLife.16654, 2016

VonDran, M.W., J. LaFrancois, V.A. Padow, W.J. Friedman, H.E. Scharfman, T.A. Milner, B.L. Hempstead, ProBDNF, but not proNGF, is upregulated following seizures in mice, ASN Neuro, Sep 25;6(5): 1759091414552185. doi: 10.1177/1759091414552185, 2014

Friedman, W.J., A.P. Le, S. Choi, and M. Volosin, Seizures tip the balance of neurotrophin signaling towards neuronal death, in Handbook of Neurotoxicology “Physiology and pathophysiology of neurotrophins”, (R.M Kostrzewa, ed.) Springer, pp. 1945-1953, 2014

Choi, S. and W.J. Friedman, Interleukin-1b enhances neuronal vulnerability to proNGF-mediated apoptosis by increasing surface expression of p75NTR and sortilin, Neuroscience, 257:11-19, 2014