Skip to main content


This project investigates the effects of TLR9 and TLR7 ligands on locomotor, pain, and bladder dysfunction in mice sustaining a contusion injury.  The TLR ligands are delivered intrathecally.  Injury is induced by the use of the Infinite Horizon Impactor.  The locomotor function is assessed by open field activity and Catwalk.  Chronic pain is assessed by evaluating thermal hypersensitivity using the paw withdrawal and tail-flick tests to a thermal stimulus.


Related Publications:


Related Faculty & Staff: