Clinical Interest: My primary clinical interest involves the management of aggressive and therapeutic resistance cancers such as glioblastoma, pancreatic cancer, triple-negative breast cancer (TNBC), sarcoma, diffuse intrinsic pontine glioma, small cell lung cancer, head and neck cancer, and castration-resistant prostate cancer.
Research Interest: To advance my clinical interest, my research has focused on targeting a chemoradiotherapy-resistant subpopulation of cancer cells by leveraging phage display-derived peptides and genomics-guided precision oncology.
Publication List:
Peer-Reviewed Articles
Huang Q, Xiao D, Liu L, Huang Z, Wang W, Zhai K, Kim J, Liu J, Liang W, He J, Bao S “CD44+ Lung Cancer Stem Cell-derived Pericytes-like Cells Cause Brain Metastases through GPR124-enhanced Trans-endothelial Migration.” Cancer Cell, 2023 Sep; (online ahead of print). PMID: 37595587
Kim J, Potez M, She C, Huang P, Wu Q, Bao S, Rich J, Liu JK. “Glioblastoma stem cell targeting peptide isolated through phage display binds cadherin 2.” Stem Cells, 2023 Aug; 41(8):762-774. PMID: 37280108
Kumar R, Kim J, Deek M, Gulhati P, In H, Kennedy T, Shah M, Grandhi M, Berim L, Spencer K, Langan R, Hochster H, Boland P, Jabbour R. “Combination of Immunotherapy and Radiation Therapy in Gastrointestinal Cancers: An Appraisal of Current Literature and Ongoing Research.” Current Oncology, 2023 Jul 5;30(7):6432-6446. PMID: 37504333
Kim J, Mukherji S, Haigentz M, Stubbs V, Kim S. “A rare pattern of local recurrence in the nasopharyngeal carcinoma: Case Report.” Otolaryngology Case Reports, 2023 June; 27: 100518
Kim J, Haffty B. “Genetic factors in the screening and imaging for breast cancer.” Korean Journal of Radiology, 2023 May; 24(5):378-383. PMID: 37056158
Potez M, Snedal S, She C, Kim J, Thorner K, Tran T, Ramello MC, Abate-Daga D, Liu JK. “Use of phage display biopanning as a tool to design CAR-T cells against glioma stem cells.” Frontiers in Oncology, 2023 Mar 24;13:1124272. PMID: 37035164
Kim J, She C, Potez M, Huang P, Wu Q, Prager B, Qiu Z, Bao S, Rich J, Liu JK. “Phage display targeting identifies EYA1 as a regulator of glioblastoma stem cell maintenance and proliferation.” Stem Cells, 2021 Jul; 39(7):853-865. PMID: 33594762
Lee GT, Kwon SJ, Kim J, Kwon YS, Lee N, Hong JH, Jamieson C, Kim WJ, Kim IY. “WNT5A induces castration-resistant prostate cancer via CCL2 and tumor-infiltrating macrophages.” British Journal of Cancer, 2018 Mar; 118(5):670-678. PMID: 29381686
Yu J, Kwon YS, Kim S, Han CS, Farber N, Kim J, Byun SS, Kim W, Jeon SS, Kim IY. “Pathological outcome following radical prostatectomy in men with PSA greater than 10 ng/ml and histologically very low-risk prostate cancer.” Journal of Urology,
2016 May; 195(5):1464-70. PMID: 26608903
Kim J, Cho HH, Lee SY, Hong CP, Yang JW, Kim YS, Suh KT, Jung JS. “Role of IRAK1 on TNF-induced proliferation and NF-kappaB activation in human bone marrow mesenchymal stem cells.” Cellular Physiology and Biochemistry, 2012 Jun; 30(1): 49-60. PMID: 22759955
Kim J, Yu JM, Bae YC, Jung JS. “Analysis of global gene expression profile of human adipose tissue derived mesenchymal stem cell cultured with cancer cells.” Journal of Life Science, 2011 May; 21(5): 631-46.
Kim J, Song JS, Cho HH, Shin KK, Bae YC, Lee BJ, Jung JS. “Effect of the modulation of leucine zipper tumor suppressor 2 expression on proliferation of various cancer cells functions as a tumor suppressor.” Molecular and Cellular Biochemistry, 2011 Jan; 346(1-2): 125-36. PMID: 20890637
Cho HH, Shin KK, Kim YJ, Song JS, Kim J, Bae YC, Kim CD, Jung JS. “NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression.” Journal of Cellular Physiology, 2010 Apr; 223(1): 168-77. PMID: 20049872
Peer-Reviewed Published Abstracts
Kim J, Kumar R, Hathout L, Jabbour S, Deek M. “Comprehensive genomic analysis stratified by KRAS status in patients with pancreatic adenocarcinoma and its prognostic significance.” Int J Radiat Oncol Biol Phys, 2023 (accepted)
Kim J, Kumar R, Hathout L, Jabbour S, Deek M. “The landscape of genetic alterations associated with metachronous metastasis in patients with pancreatic ductal adenocarcinoma and its prognostic significance.” Int J Radiat Oncol Biol Phys, 2023 (accepted)
Kim J, Harris A, Moore D, Jabbour S, Deek M, Pitt H, Saraiya B, Ennis R. “Unplanned hospitalization and subsequent mortality in lung cancer patients undergoing concomitant chemo-/immuno-therapy and radiotherapy: an analysis of over 10,000 patients in a nationwide database.” Int J Radiat Oncol Biol Phys, 2023 (accepted)
Kumar R, Almeldin D, Kim J, Deek M, Jabbour S. “Predictive value of dynamic tumor volume changes in stage III non-small cell lung cancer treated with chemoradiation and consolidative immunotherapy.” Int J Radiat Oncol Biol Phys, 2023 (accepted)
Kumar R, Neibart S, Kim J, Manidanna S, Deek M, Jabbour S. “Predictive value of tumor volume on local control in hepatocellular carcinoma treated with image guided hypofractionated radiation treatment.” Int J Radiat Oncol Biol Phys, 2023 (accepted)
Kim J, Peperdi H, Jabbour S, Deek M. “The landscape of genetic alterations based on TP53 status in patients with pancreatic adenocarcinoma and its prognostic significance.” Int J Radiat Oncol Biol Phys, 2022 Nov, Volume 114.
She C, Kim J, Potez M, James Liu, “Phage display biopanning identifies AMOT regulating cell motility of brain metastatic stem-like cells.” Neuro-Oncology, 2021 Nov, Volume 23.
She C, Potez M, Kim J, James Liu, “Phage display biopanning identifies AMOT regulating cell motility in brain metastasis-initiating cells.” Neuro-Oncology Advances, 2021 Aug, Volume 3. PMCID: PMC8351267
Potez M, Kim J, She C, Chaudhary N, James Liu, “In vivo phage display identifies peptide targeting N-cadherin on glioma stem cells.” Neuro-Oncology, 2020 Nov, Volume 22. PMCID: PMC7651257
Potez M, Snedal S, Kim J, Thorner K, Ramello M, Abate-Daga D, James Liu “Glioblastoma stem cell targeting chimeric antigen receptor T cells modified using phage display isolated peptides.” Neuro-Oncology, 2020 Nov, Volume 22. PMCID: PMC7651385
Kim J, Liu J, “Metastatic brain tumor imaging through targeted peptides isolated via phage display biopanning against brain metastasis-initiating cells.” Neuro-Oncology, 2019 Nov, Volume 21. PMCID: PMC6847290
Kim J, Liu J, “Metastatic brain tumor targeting peptides isolated through phage display biopanning against brain metastasis-initiating cells.” Neuro-Oncology Advances, 2019 Aug, Volume 1. PMCID: PMC7213402
Kim J, Bao S, Rich J, Liu JK “Novel metastatic brain tumor targets isolated through phage display biopanning against brain metastasis-initiating cells.” Neuro-Oncology, 2018 Nov, Volume 20. PMCID: PMC6216512
Kim J, Huang P, Rich J, Liu JK “Visualization of brain tumor by near-infrared fluorescence imaging via tumor-targeting novel peptide identified by phage display.” Neuro-Oncology, 2017 Nov; 19(suppl_6): vi269. PMCID: PMC5692683
Kim J, Rich J, Liu JK “Imaging glioblastoma stem cells with 7-amino acid-length tumor-homing peptide identified by phage display biopanning.” Neuro-Oncology, 2017 Nov; 19(suppl_6): vi89. PMCID: PMC5693155
Kim J, Xie Q, Rich J, Liu JK “Renin-angiotensin system identified by phage display screening is a new therapeutic target for glioblastoma and regulates proliferation of glioblastoma stem cells.” Neuro-Oncology, 2017 Nov; 19(suppl_6): vi230. PMCID: PMC5693162
Kwon YS, Kang S, Wang W, Farber NJ, Radadia K, Lee P, Kim J, Hong JH, Kim IY “Misattribution errors in urologic procedures from the ProPublica Surgeon Scorecard.” Journal of Urology, 2016 Apr; 195(4S): e499-e500.
Kwon YS, Farber NJ, Yu JW, Han CS, Lee P, Kim J, Kim W, Kim, IY “Longitudinal recovery patterns of penile length and the underexplored benefit of long-term phosphodiesterase inhibitor use after radical prostatectomy.” Journal of Urology, 2016 Apr; 195(4S): e1189.
Awards:
2023 ASTRO Annual Meeting Resident Recognition Award (Biology), American Society for
Radiation Oncology
2023 KASTRO Robert Y. Kim MD Annual U.S. Resident/Fellow Research Grant Award, Korean
American Society for Radiation Oncology
2022 RSNA Roentgen Fellow/Resident Research Award, Radiological Society of North America
Hobbies:
Guitar playing, hiking, and LEGO building