In a recent PBS Think Tank with Steve Adubato interview, neurologist Dr. William Hu, offered clarity on one of the most puzzling consequences of the COVID-19 pandemic: persistent “brain fog.” Drawing on his team’s research, Dr. Hu emphasized that while many post-COVID patients experience lingering cognitive difficulties, these symptoms are not indicative of early-onset Alzheimer’s disease, which unfolds over decades rather than weeks or months. Instead, his findings suggest that long COVID may involve a distinct chronic infection-like signature in the nervous system, reflecting ongoing physiological effects even after the initial virus has cleared. Dr. Hu also highlighted the real uncertainty that remains for half of patients whose symptoms persist years later, underscoring the need for continued research and clearer treatment strategies for those affected.