Publications
1: Zhang X, Bandyopadhyay S, Araujo LP, Tong K, Flores J, Laubitz D, Zhao Y, Yap
G, Wang J, Zou Q, Ferraris R, Zhang L, Hu W, Bonder EM, Kiela PR, Coffey R,
Verzi MP, Ivanov II, Gao N. Elevating EGFR-MAPK program by a nonconventional
Cdc42 enhances intestinal epithelial survival and regeneration. JCI Insight.
2020 Aug 20;5(16):135923. doi: 10.1172/jci.insight.135923. PMID: 32686657.
2: Yu S, Balasubramanian I, Laubitz D, Tong K, Bandyopadhyay S, Lin X, Flores J,
Singh R, Liu Y, Macazana C, Zhao Y, Béguet-Crespel F, Patil K, Midura-Kiela MT,
Wang D, Yap GS, Ferraris RP, Wei Z, Bonder EM, Häggblom MM, Zhang L, Douard V,
Verzi MP, Cadwell K, Kiela PR, Gao N. Paneth Cell-Derived Lysozyme Defines the
Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine.
Immunity. 2020 Aug 18;53(2):398-416.e8. doi: 10.1016/j.immuni.2020.07.010.
3: Al-Jawadi A, Patel CR, Shiarella RJ, Romelus E, Auvinen M, Guardia J, Pearce
SC, Kishida K, Yu S, Gao N, Ferraris RP. Cell-Type-Specific, Ketohexokinase-
Dependent Induction by Fructose of Lipogenic Gene Expression in Mouse Small
Intestine. J Nutr. 2020 Jul 1;150(7):1722-1730. doi: 10.1093/jn/nxaa113. PMID:
32386219; PMCID: PMC7330472.
4: Singh R, Balasubramanian I, Zhang L, Gao N. Metaplastic Paneth Cells in
Extra-Intestinal Mucosal Niche Indicate a Link to Microbiome and Inflammation.
Front Physiol. 2020 Mar 31;11:280. doi: 10.3389/fphys.2020.00280. PMID:
32296343; PMCID: PMC7138011.
5: Chen L, Vasoya RP, Toke NH, Parthasarathy A, Luo S, Chiles E, Flores J, Gao
N, Bonder EM, Su X, Verzi MP. HNF4 Regulates Fatty Acid Oxidation and Is
Required for Renewal of Intestinal Stem Cells in Mice. Gastroenterology. 2020
Mar;158(4):985-999.e9. doi: 10.1053/j.gastro.2019.11.031. Epub 2019 Nov 22.
PMID: 31759926; PMCID: PMC7062567.
6: D’Agostino L, Nie Y, Goswami S, Tong K, Yu S, Bandyopadhyay S, Flores J,
Zhang X, Balasubramanian I, Joseph I, Sakamori R, Farrell V, Li Q, Yang CS, Gao
B, Ferraris RP, Yehia G, Bonder EM, Goldenring JR, Verzi MP, Zhang L, Ip YT, Gao
Recycling Endosomes in Mature Epithelia Restrain Tumorigenic Signaling.
Cancer Res. 2019 Aug 15;79(16):4099-4112. doi: 10.1158/0008-5472.CAN-18-4075.
Epub 2019 Jun 25. PMID: 31239271; PMCID: PMC6726494.
7: Ladinsky MS, Araujo LP, Zhang X, Veltri J, Galan-Diez M, Soualhi S, Lee C,
Irie K, Pinker EY, Narushima S, Bandyopadhyay S, Nagayama M, Elhenawy W, Coombes
BK, Ferraris RP, Honda K, Iliev ID, Gao N, Bjorkman PJ, Ivanov II. Endocytosis
of commensal antigens by intestinal epithelial cells regulates mucosal T cell
homeostasis. Science. 2019 Mar 8;363(6431):eaat4042. doi:
10.1126/science.aat4042. PMID: 30846568; PMCID: PMC6708280.
8: Lee YS, Kim TY, Kim Y, Lee SH, Kim S, Kang SW, Yang JY, Baek IJ, Sung YH,
Park YY, Hwang SW, O E, Kim KS, Liu S, Kamada N, Gao N, Kweon MN. Microbiota-
Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial
Development. Cell Host Microbe. 2018 Dec 12;24(6):833-846.e6. doi:
10.1016/j.chom.2018.11.002. PMID: 30543778.
9: Yu S, Tong K, Zhao Y, Balasubramanian I, Yap GS, Ferraris RP, Bonder EM,
Verzi MP, Gao N. Paneth Cell Multipotency Induced by Notch Activation following
Injury. Cell Stem Cell. 2018 Jul 5;23(1):46-59.e5. doi: 10.1016/j.stem.2018.05.002.
Epub 2018 Jun 7. PMID: 29887318; PMCID: PMC6035085.
10: Zhang X, Ren J, Wang J, Li S, Zou Q, Gao N. Receptor-mediated endocytosis
generates nanomechanical force reflective of ligand identity and cellular
property. J Cell Physiol. 2018 Aug;233(8):5908-5919. doi: 10.1002/jcp.26400.
Epub 2018 Feb 27. PMID: 29243828; PMCID: PMC7274725.
11: Feng Q, Bonder EM, Engevik AC, Zhang L, Tyska MJ, Goldenring JR, Gao N.
Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in
neonatal enteropathy. J Cell Sci. 2017 Aug 1;130(15):2491-2505. doi:
10.1242/jcs.201897. Epub 2017 Jun 8. Erratum in: J Cell Sci. 2018 Sep
17;131(18): PMID: 28596241; PMCID: PMC5558269.
12: Sun J, Yu S, Zhang X, Capac C, Aligbe O, Daudelin T, Bonder EM, Gao N. A
Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle
assembly and mature ligand export. J Cell Sci. 2017 Jul 1;130(13):2159-2171.
doi: 10.1242/jcs.200634. Epub 2017 May 17. PMID: 28515233; PMCID: PMC5536887.
13: Balasubramanian I, Gao N. From sensing to shaping microbiota: insights into
the role of NOD2 in intestinal homeostasis and progression of Crohn’s disease.
Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G7-G13. doi:
10.1152/ajpgi.00330.2016. Epub 2017 Apr 27. PMID: 28450278; PMCID: PMC5538831.
14: Das S, Yu S, Sakamori R, Vedula P, Feng Q, Flores J, Hoffman A, Fu J,
Stypulkowski E, Rodriguez A, Dobrowolski R, Harada A, Hsu W, Bonder EM, Verzi
MP, Gao N. Rab8a vesicles regulate Wnt ligand delivery and Paneth cell
maturation at the intestinal stem cell niche. Development. 2015 Jun
15;142(12):2147-62. doi: 10.1242/dev.121046. Epub 2015 May 26. PMID: 26015543;
PMCID: PMC4483769.
15: Yu S, Yehia G, Wang J, Stypulkowski E, Sakamori R, Jiang P, Hernandez-
Enriquez B, Tran TS, Bonder EM, Guo W, Gao N. Global ablation of the mouse
Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion.
J Biol Chem. 2014 Nov 14;289(46):32030-43. doi: 10.1074/jbc.M113.538223. Epub
2014 Sep 30. PMID: 25271168; PMCID: PMC4231680.
16: Sakamori R, Yu S, Zhang X, Hoffman A, Sun J, Das S, Vedula P, Li G, Fu J,
Walker F, Yang CS, Yi Z, Hsu W, Yu DH, Shen L, Rodriguez AJ, Taketo MM, Bonder
EM, Verzi MP, Gao N. CDC42 inhibition suppresses progression of incipient
intestinal tumors. Cancer Res. 2014 Oct 1;74(19):5480-92. doi:
10.1158/0008-5472.CAN-14-0267. Epub 2014 Aug 11. PMID: 25113996; PMCID:
PMC4184946.
17: Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard
V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N. TLR sorting by Rab11
endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014
Sep 1;33(17):1882-95. doi: 10.15252/embj.201487888. Epub 2014 Jul 24. PMID:
25063677; PMCID: PMC4195784.