Skip to main content

Publications

  1. Turano, P.S., Akbulut, E., Dewald, H.K., Vasilopoulos, T., Fitzgerald-Bocarsly, P., Herbig, U., and Martinez-Zamudio, R.I. (2025). Age-independent and targetable transcription factor networks regulating CD8(+) T cell senescence in aging humans. Cell Rep 45, 116795. 10.1016/j.celrep.2025.116795.
  2. Turano, P.S., Akbulut, E., Aquino, N.M., Garza-Martinez, L., Singh, S., Yap, G.S., Fitzgerald-Bocarsly, P., Martinez-Zamudio, R.I., and Herbig, U. (2025). Senescent CD8 T Effector Memory Cells are Functionally Impaired, Enriched in Aging and Disease, and a Barrier to Immunotherapy. bioRxiv. 10.64898/2025.12.16.694716.
  3. Marmisolle, I., Chacon, E., Mansilla, S., Ruiz, S., Bresque, M., Martinez, J., Martinez-Zamudio, R.I., Herbig, U., Liu, J., Finkel, T., et al. (2025). Oncogene-induced senescence mitochondrial metabolism and bioenergetics drive the secretory phenotype: further characterization and comparison with other senescence-inducing stimuli. Redox Biol 82, 103606. 10.1016/j.redox.2025.103606.
  4. Vasilopoulos, T., and Martinez-Zamudio, R.I. (2024). Transcription factor network dynamics during the commitment to oncogene-induced senescence. Frontiers in Epigenetics and Epigenomics 2. https://doi.org/10.3389/freae.2024.1423454. 
  5. Martinez-Zamudio, R.I., Stefa, A., Nabuco Leva Ferreira Freitas, J.A., Vasilopoulos, T., Simpson, M., Dore, G., Roux, P.F., Galan, M.A., Chokshi, R.J., Bischof, O., and Herbig, U. (2023). Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars. Cell Genom 3, 100293. 10.1016/j.xgen.2023.100293.
  6. Martinez-Zamudio, R.I., Dewald, H.K., Vasilopoulos, T., Gittens-Williams, L., Fitzgerald-Bocarsly, P., and Herbig, U. (2021). Senescence-associated beta-galactosidase reveals the abundance of senescent CD8+ T cells in aging humans. Aging Cell 20, e13344. 10.1111/acel.13344.
  7. Martinez-Zamudio, R.I., Roux, P.F., de Freitas, J., Robinson, L., Dore, G., Sun, B., Belenki, D., Milanovic, M., Herbig, U., Schmitt, C.A., et al. (2020). AP-1 imprints a reversible transcriptional programme of senescent cells. Nat Cell Biol 22, 842–855. 10.1038/s41556-020-0529-5.
  8. Martínez-Zamudio, R.I., and Herbig, U. (2019). Cell Senescence. In Encyclopedia of Gerontology and Population Aging, D. Gu, and M.E. Dupre, eds. (Springer International Publishing), pp. 1–15. 10.1007/978-3-319-69892-2_38-1.
  9. Martinez-Zamudio, R.I., Robinson, L., Roux, P.F., and Bischof, O. (2017). SnapShot: Cellular Senescence Pathways. Cell 170, 816–816 e811. 10.1016/j.cell.2017.07.049.
  10. Martinez-Zamudio, R.I., Robinson, L., Roux, P.F., and Bischof, O. (2017). SnapShot: Cellular Senescence in Pathophysiology. Cell 170, 1044–1044 e1041. 10.1016/j.cell.2017.08.025.
  11. Bischof, O., and Martinez-Zamudio, R.I. (2015). MicroRNAs and lncRNAs in senescence: A re-view. IUBMB Life 67, 255–267. 10.1002/iub.1373.
  12. Martinez-Zamudio, R.I., and Ha, H.C. (2014). PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia. Brain Behav 4, 552–565. 10.1002/brb3.239.
  13. Martinez-Zamudio, R., and Ha, H.C. (2012). Histone ADP-ribosylation facilitates gene transcription by directly remodeling nucleosomes. Mol Cell Biol 32, 2490–2502. 10.1128/MCB.06667-11.
  14. Martinez-Zamudio, R., and Ha, H.C. (2011). Environmental epigenetics in metal exposure. Epigenetics 6, 820–827. 10.4161/epi.6.7.16250.