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Aspirating protein droplets

Huan’s paper on using micropipette aspiration to quantify the surface tension and viscosity of liquid protein condensates is now published on the first issue of Biophysical Reports! She showed that the properties of protein condensates are very much different from any common liquids that we are familiar with in everyday life. Micropipette aspiration, a technique that doesn’t work very well on measuring common liquids, was able to accurately quantify droplets of an RNA binding domain of the P granule RNA helicase LAF-1. Plus, both surface tension and viscosity of the droplets are measured in one experiment! Great collaboration with Ben Schuster’s lab and Drago Milovanovic!