“Breaking Speed and Resolution Limitations of High-Speed AFM for Membrane Protein Structure-Function Analysis” Simon Scheuring1,2,* 1 Weill Cornell Medicine, Department of Anesthesiology, 1300 York Avenue, New York, NY-10065, USA. 2 Weill Cornell Medicine, Department of Physiology and Biophysics, 1300 York Avenue, New York, NY-10065, USA High-speed atomic force microscopy (HS-AFM) is a powerful technique that … Read More
Condensate Biology at the Synapse Brain functioning critically relies on neuronal communication that mainly occurs by chemical signaling at the specialized contacts known as synapses. At synapses, messenger molecules are … Read More
Electronic and molecular approaches for neural recording: deciphering the brain in space and time Resolving neuronal activity in space and time is a long-sought capability in neuroscience, which is, however, still … Read More
Single-molecule biophysical approaches to studying the mechanisms of motor proteins Ribosomes are molecular machines made of protein and RNA that translate mRNA into proteins. The biogenesis of new ribosomes is … Read More
LC-MS Metabolomics Reveals the Role of SLC45A4 in GABA de novo Synthesis Affiliations: 1Departments of Medicine, Division of Endocrinology, Robert Wood Johnson Medical School, Rutgers University; 2Metabolomics Shared Resource, Rutgers Cancer Institute … Read More
Modulation of amyloid assembly by chaperone-like proteins Soluble proteins have an inherent propensity to undergo altered protein folding, forming cross-B sheet-rich structures called amyloids. Amyloid fibrils have gained significant attention … Read More