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A review of condensates

As part of her thesis, Huan systematically reviewed the rheology and interfacial properties of biomolecular condensates. In addition to summarizing quantitative measurements in the literature, we also tried point out … Read More

An executioner of cell death

In collaboration with Jie Xu’s lab, Yiling studied how a protein called “NINJ1” regulates the rupture of cell plasma membranes. We found that having more NINJ1 drastically reduces the lysis … Read More

Quantifying cell membrane protrusions

Shilong and Zheng wrote a book chapter, detailing the steps to quantify cell membrane protrusions (and the sorting of proteins on them) using simple widefield fluorescence images. Read it here!

Curvature and Mechanosensing

Shilong found that the shape of cell membrane directly regulates the distribution of Piezo1, a widely expressed mechanosensitive ion channel, within a cell. Piezo1 may flatten upon activation and can … Read More

Tension along an axon

Our study on the membrane of neuronal axons is now published on Science Advances! We found that membrane tension propagates at a surprisingly fast speed (20 microns/s!) along the axons of … Read More

Huan’s paper in the news

Huan’s paper on quantifying the surface tension and viscosity of protein condensates has been picked up by a wide range of news outlets, including: EurekAlert!, ScienceDaily, News wise, Phys.org, Neuroscience … Read More