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Investigating underlying human immunity genes, implicated diseases and their relationship to COVID-19

Abstract Aim: A human immunogenetics variation study was conducted in samples collected from diverse COVID-19 populations. Materials & methods: Whole-genome and whole-exome sequencing (WGS/WES), data processing, analysis and visualization pipeline were applied to identify variants associated with genes of interest. Results: A total of 2886 mutations were found across the entire set of 13 genomes. … Read More

Precision medicine with multi-omics strategies, deep phenotyping, and predictive analysis

Precision medicine is driven by the paradigm shift of empowering clinicians to predict the most appropriate course of action for patients with complex diseases and to improve routine medical and public health practice. Understanding patients’ multi-omics make-up in conjunction with the clinical data will lead to determining predisposition, diagnostic, prognostic and predictive biomarkers and to … Read More

Multi-omics strategies for personalized and predictive medicine: past, current, and future translational opportunities

Precision medicine is driven by the paradigm shift of empowering clinicians to predict the most appropriate course of action for patients with complex diseases and improve routine medical and public health practice. It promotes integrating collective and individualized clinical data with patient specific multi-omics data to develop therapeutic strategies, and knowledgebase for predictive and personalized … Read More

Artificial Intelligence for Personalized and Predictive Genomics Data Analysis.

About this Research Topic This special issue features Artificial Intelligence, Machine Learning, Genomics and Precision Medicine, and invites relevant high-quality original research, systematic review, methods, review, mini review, perspective, case report, data report, policy brief, general commentary, opinion, and editorial article for the transparent peer review and publication. The quest to understand what causes chronic, … Read More