Papers
2020
Burrell J. C., Bhatnagar D., Brown D. P., Murthy N. S., Dutton J., Browne K. D., Laimo F. A., Ali Z., Rosen J.M., Kaplan H.M., Kohn j., Cullen D. K. Tyrosine-Derived Polycarbonate Nerve Guidance Tubes Elicit Pro-Regenerative Extracellular Matrix Deposition When Used to Bridge Segmental Nerve Defects in Swine. Journal of Biomed. Mat. Res. Part A (2020)
Sven D. Sommerfeld, N. Sanjeeva Murthy, Jarrod Cohen, Zheng Zhang, James A. Kaduk and Joachim Kohn Structural investigations of polycarbonates whose mechanical and erosion behavior can be controlled by their isomer sequence Macromolecules 53:9878-9889 doi.org/10.1021/acs.macromol.0c01772 (2020)
Carly M. Garrison, Anya Singh-Varma, Alexandra K. Pastino, Joseph A. M. Steele, Joachim Kohn, N. Sanjeeva Murthy and Jean E. Schwarzbauer A multilayered scaffold for regeneration of smooth muscle and connective tissue layers J Biomed Mater Res. 1–12 DOI: 10.1002/jbm.a.37058 (2020)
Shruti Saxena, Wei Chang, Amir Fakhrzadeh, N. Sanjeeva Murthy, Weibo Zhang, Joachim Kohn and Pamela C. Yelick Calcium phosphate enriched synthetic tyrosine-derived polycarbonate – dicalcium phosphate dihydrate polymer scaffolds for enhanced bone regeneration Materialia 9:100616 (2020).
Amish Patel, Mariana R. N. Lima, Hyeon-Yeol Cho, Ki-Bum Lee, N. Sanjeeva Murthy, and Joachim Kohn Disassembly of Nanospheres with a PEG Shell Upon Adsorption onto PEGylated Substrates Langmuir 36:232-241 (2020).
Joseph Molde, Joseph A.M. Steele, Alexandra Pastino, Anisha Mahat, N. Sanjeeva Murthy, and Joachim Kohn. A step toward engineering thick tissues: Distributing Microfibers within 3D Printed Frames Journal of Biomedical Materials Research: Part A108A:581-591 (2020).
Gama AR, Ng ZY, Shanmugarajah K, Mastroianni M, Randolph MA, Lellouch AG, Kohn J, Cetrulo CL.Local Immunosuppression for Vascularized Composite Allografts: Application of Topical FK506-TyroSpheres in a Non-Human Primate Model.J Burn Care Res. 2020 Apr 30:iraa062.
Sonseca A, Sahay R, Stepien K, Bukala J, Wcislek A, McClain A, Sobolewski P, Sui X, Puskas JE, Kohn J, Wagner HD, El Fray M. Architectured helically coiled scaffolds from elastomeric poly(butylene succinate) (PBS) copolyester via wet electrospinning.Mater Sci Eng C Mater Biol Appl. 2020 Mar;108:110505.
Patel A, Lima MRN, Cho HY, Lee KB, Murthy NS, Kohn J.Disassembly of Nanospheres with a PEG Shell upon Adsorption onto PEGylated Substrates.Langmuir. 2020 Jan 14;36(1):232-241.
Molde J, Steele JAM, Pastino AK, Mahat A, Murthy NS, Kohn J.A step toward engineering thick tissues: Distributing microfibers within 3D printed frames.J Biomed Mater Res A. 2020 Mar;108(3):581-591.
2019
Puertas-Bartolomé M, Benito-Garzón L, Fung S, Kohn J, Vázquez-Lasa B, San Román J.Bioadhesive functional hydrogels: Controlled release of catechol species with antioxidant and antiinflammatory behavior.Mater Sci Eng C Mater Biol Appl. 2019 Dec;105:110040.
Fung SL, Wu X, Maceren JP, Mao Y, Kohn J.In Vitro Evaluation of Recombinant Bone Morphogenetic Protein-2 Bioactivity for Regenerative Medicine.Tissue Eng Part C Methods. 2019 Sep;25(9):553-559.
Murthy NS, Wang W, Sommerfeld SD, Vaknin D, Kohn J.Temperature-Activated PEG Surface Segregation Controls the Protein Repellency of Polymers.Langmuir. 2019 Jul 30;35(30):9769-9776.
Sobolewski P, Murthy NS, Kohn J, El Fray M.Adsorption of Fibrinogen and Fibronectin on Elastomeric Poly(butylene succinate) Copolyesters.Langmuir. 2019 Jul 2;35(26):8850-8859.
Mao Y, Hoffman T, Dhall S, Singal A, Sathyamoorthy M, Danilkovitch A, Kohn J.Endogenous viable cells in lyopreserved amnion retain differentiation potential and anti-fibrotic activity in vitro.Acta Biomater. 2019 Aug;94:330-339.
Mao Y, Pierce J, Singh-Varma A, Boyer M, Kohn J, Reems JA.Processed human amniotic fluid retains its antibacterial activity.J Transl Med. 2019 Mar 1;17(1):68.
Merolli A, Mao Y, Voronin G, Steele JAM, Murthy NS, Kohn J.A method to deliver patterned electrical impulses to Schwann cells cultured on an artificial axon.
Neural Regen Res. 2019 Jun;14(6):1052-1059.
Ji S , Dube K , Chesterman JP , Fung SL , Liaw CY , Kohn J , Guvendiren M .Polyester-based ink platform with tunable bioactivity for 3D printing of tissue engineering scaffolds.Biomater Sci. 2019 Jan 29;7(2):560-570.
Mao Y, Block T, Singh-Varma A, Sheldrake A, Leeth R, Griffey S, Kohn J.Extracellular matrix derived from chondrocytes promotes rapid expansion of human primary chondrocytes in vitro with reduced dedifferentiation.Acta Biomater. 2019 Feb;85:75-83.
2018
Grinstaff MW, Kaplan HM, Kohn J.Predoctoral and Postdoctoral Training Pipeline in Translational Biomaterials Research and Regenerative Medicine.ACS Biomater Sci Eng. 2018 Dec 10;4(12):3919-3926.
Merolli A, Louro P, Kohn J.Reciprocal nerve staining (RNS) for the concurrent detection of choline acetyltransferase and myelin basic protein on paraffin-embedded sections.J Neurosci Methods. 2019 Jan 1;311:235-238.
Vega SL, Arvind V, Mishra P, Kohn J, Sanjeeva Murthy N, Moghe PV.Substrate micropatterns produced by polymer demixing regulate focal adhesions, actin anisotropy, and lineage differentiation of stem cells.Acta Biomater. 2018 Aug;76:21-28.
Merolli A, Fung S, Murthy NS, Pashuck ET, Mao Y, Wu X, Steele JAM, Martin D, Moghe PV, Bromage T, Kohn J.“Ruffled border” formation on a CaP-free substrate: A first step towards osteoclast-recruiting bone-grafts materials able to re-establish bone turn-over.
J Mater Sci Mater Med. 2018 Mar 21;29(4):38.
Lo MC, Wang S, Singh S, Damodaran VB, Ahmed I, Coffey K, Barker D, Saste K, Kals K, Kaplan HM, Kohn J, Shreiber DI, Zahn JD.Evaluating the in vivo glial response to miniaturized parylene cortical probes coated with an ultra-fast degrading polymer to aid insertion.J Neural Eng. 2018 Jun;15(3):036002.
Pastino A, Steele J, Kohn J.Advancing biomaterials towards biological complexity.Biochem (Lond). 2018 Feb;40(1):16-19.
Murthy NS , Zhang Z , Borsadia S , Kohn J .Nanospheres with a smectic hydrophobic core and an amorphous PEG hydrophilic shell: structural changes and implications for drug delivery.Soft Matter. 2018 Feb 21;14(8):1327-1335.
Mao Y, Singh-Varma A, Hoffman T, Dhall S, Danilkovitch A, Kohn J.The Effect of Cryopreserved Human Placental Tissues on Biofilm Formation of Wound-Associated Pathogens.J Funct Biomater. 2018 Jan 8;9(1):3.
Mao Y, Hoffman T, Wu A, Kohn J.An Innovative Laboratory Procedure to Expand Chondrocytes with Reduced Dedifferentiation.Cartilage. 2018 Apr;9(2):202-211.
Guerrero J, Oliveira H, Aid R, Bareille R, Siadous R, Letourneur D, Mao Y, Kohn J, Amédée J.Influence of the three-dimensional culture of human bone marrow mesenchymal stromal cells within a macroporous polysaccharides scaffold on Pannexin 1 and Pannexin 3.J Tissue Eng Regen Med. 2018 Apr;12(4):e1936-e1949.
Mastroianni M, Ng ZY, Goyal R, Mallard C, Farkash EA, Leonard DA, Albritton A, Shanmugarajah K, Kurtz JM, Sachs DH, Macri LK, Kohn J, Cetrulo CL Jr.Topical Delivery of Immunosuppression to Prolong Xenogeneic and Allogeneic Split-Thickness Skin Graft Survival.Version 2. J Burn Care Res. 2018 Apr 20;39(3):363-373.
2017
Mao Y, Hoffman T, Singh-Varma A, Duan-Arnold Y, Moorman M, Danilkovitch A, Kohn J.Antimicrobial Peptides Secreted From Human Cryopreserved Viable Amniotic Membrane Contribute to its Antibacterial Activity.Sci Rep. 2017 Oct 20;7(1):13722.
Guvendiren M, Fung S, Kohn J, De Maria C, Montemurro F, Vozzi G.The control of stem cell morphology and differentiation using three-dimensional printed scaffold architecture.MRS Commun. 2017 Sep;7(3):383-390.
Martínez-Ibáñez M, Murthy NS, Mao Y, Suay J, Gurruchaga M, Goñi I, Kohn J.Enhancement of plasma protein adsorption and osteogenesis of hMSCs by functionalized siloxane coatings for titanium implants.J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1138-1147.
Mao Y, Hoffman T, Wu A, Goyal R, Kohn J.Cell type-specific extracellular matrix guided the differentiation of human mesenchymal stem cells in 3D polymeric scaffolds.J Mater Sci Mater Med. 2017 Jul;28(7):100.
Kohn-Polster C, Bhatnagar D, Woloszyn DJ, Richtmyer M, Starke A, Springwald AH, Franz S, Schulz-Siegmund M, Kaplan HM, Kohn J, Hacker MC.Dual-Component Gelatinous Peptide/Reactive Oligomer Formulations as Conduit Material and Luminal Filler for Peripheral Nerve Regeneration.Int J Mol Sci. 2017 May 21;18(5):1104.
Bhatnagar D, Bushman JS, Murthy NS, Merolli A, Kaplan HM, Kohn J.Fibrin glue as a stabilization strategy in peripheral nerve repair when using porous nerve guidance conduits.J Mater Sci Mater Med. 2017 May;28(5):79.
Goyal R, Vega ME, Pastino AK, Singh S, Guvendiren M, Kohn J, Murthy NS, Schwarzbauer JE.Development of hybrid scaffolds with natural extracellular matrix deposited within synthetic polymeric fibers.J Biomed Mater Res A. 2017 Aug;105(8):2162-2170.
Merolli A, Mao Y, Kohn J.“A suspended carbon fiber culture to model myelination by human Schwann cells.”J Mater Sci Mater Med. 2017 Apr;28(4):57.
Goyal R, Guvendiren M, Freeman O, Mao Y, Kohn J.“Optimization of Polymer-ECM Composite Scaffolds for Tissue Engineering: Effect of Cells and Culture Conditions on Polymeric Nanofiber Mats.” J Funct Biomater. 2017 Jan 11;8(1):1.
Vega SL, Liu E, Arvind V, Bushman J, Sung HJ, Becker ML, Lelièvre S, Kohn J, Vidi PA, Moghe PV.“High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation.” Exp Cell Res. 2017 Feb 1;351(1):11-23.
2016
Bhatnagar D, Dube K, Damodaran VB, Subramanian G, Aston K, Halperin F, Mao M, Pricer K, Murthy NS, Kohn J.“Effects of Terminal Sterilization on PEG-Based Bioresorbable Polymers Used in Biomedical Applications.” Macromol Mater Eng. 2016 Oct;301(10):1211-1224.
Guvendiren M, Molde J, Soares RM, Kohn J. “Designing Biomaterials for 3D Printing.” ACS Biomater Sci Eng. 2016 Oct 10;2(10):1679-1693.
Salmasi A, Lee GT, Patel N, Goyal R, Dinizo M, Kwon YS, Modi PK, Faiena I, Kim HJ, Lee N, Hannan JL, Kohn J, Kim IY. “Off-Target Effect of Sildenafil on Postsurgical Erectile Dysfunction: Alternate Pathways and Localized Delivery System.”J Sex Med. 2016 Dec;13(12):1834-1843.
Dhaliwal A, Brenner M, Wolujewicz P, Zhang Z, Mao Y, Batish M, Kohn J, Moghe PV.“Profiling stem cell states in three-dimensional biomaterial niches using high content image informatics.” Acta Biomater. 2016 Nov;45:98-109.
Chudecka-Głaz A, Szczeblińska J, Cymbaluk-Płoska A, Kohn J, El Fray M.“New poly(ester-amide) copolymers modified with polyether (PEAE) for anticancer drug encapsulation.” J Microencapsul. 2016 Dec;33(8):702-711.
Sun, Y. Chen, X. Ma, Y. Yuan, C. Liu, J. Kohn and J. Qian, “Mitochondria-targeted Hydroxyapatite Nanoparticles for Selective Growth Inhibition of Lung Cancer in Vitro and in Vivo”, ACS App Mat Interfaces, 2016, Oct 5;8(39):25680-25690
Salmasi, N. Patel, G. T. Lee, R. Goyal, M. Dinizo, Y. S. Kwon, P. K. Modi, I. Faiena, J. L. Hannan, J. Kohn and I. Y. Kim, “Challenging the Paradigm of PDE-5 inhibitors use for Post-Surgical Erectile Dysfunction: Alternate Pathways and Localized Delivery System”, Journal of Sexual Medicine, 2016, In Press.
M. Patel, A. R. Merriam, J. Kohn, C. J. Gatt and M. G. P. D. Dunn, “Negative outcomes of PLLA fiber-reinforced scaffolds in an ovine total meniscus replacement model”, Tissue Eng Part A, 2016, Sep;22(17-18):1116-1125
Mao, T. Hoffman, A. Johnson, Y. Duan-Arnold, A. Danilkovitch and J. Kohn, “Human cryopreserved viable amniotic membrane inhibits the growth of bacteria associated with chronic wounds”, Journal of Diabetic Foot Complications, 2016, In Press.
Kohn, J. M. Klemens, C. Kascholke, N. S. Murthy, J. Kohn, M. Brandenburger and M. C. Hacker, “Tubular Conduits from Oligomer-Cross-Linked Hydrogels- Potential Nerve Guidance Materials”, Advanced Healthcare Materials, 2016,4, 1605-1621
Dhaliwal, M. Brenner, P. Wolujewicz, Z. Zhang, Y. Mao, M. Batish, J. Kohn and P. V. Moghe, “Profiling Stem Cells in Three Dimensional Biomaterial Niches using High Content Image Informatics”, Acta Biomat., 2016, Nov;45:98-109.
Chudecka-Glaz, J. Szczeblinska, A. Cymbaluk-Ploska, J. Kohn and M. El Fray, “New poly(ester-amide) copolymers modified with polyether (PEAE) for anticancer drug delivery systems”, J of Microencapsulation, 2016, 1-28.
B. Zhang, Z. Zhang, S. Chen, L. Macri, J. Kohn and P. C. Yelick, “Mandibular jaw bone regeneration using human dental cell-seeded tyrosine-derived polycarbonate scaffolds”, J of Tissue Engineeering, Part A, 2016, 22(13/14), 985-993.
M. Valenzuela, D. Knight and J. Kohn, “Developing a suitable model for water uptake for biodegradable polymers using small training sets”, Intl J of Biomaterials, 2016, 1-11.
Singh, M. C. Lo, V. B. Damodaran, H. M. Kaplan, J. Kohn, J. Zahn and D. Shreiber, “Modeling the insertion mechnanics of flexible neural probes coated with sacrificial polymers for optimizing probe design”, Sensors, 2016, 16, 1-18.
Molde, R. Soares, M. Guvendiren and J. Kohn, “Designing Biomaterials for 3D Printing”, ACS Biomat Sci Engin, 2016.
Macri, A. J. Singer, S. A. McClain, L. Crawford, A. Prasad, J. Kohn and R. A. F. Clark, “Immediate tangential excision accelerates wound closure but does not reduce scarring of mid-dermal porcine burns”, Annals of Burns and Fire Disasters, 2016, 54-61.
Groen, M. Guvendiren, H. Rabitz, W. J. Welsh, J. Kohn and J. de Boer, “Stepping into the omics era: opportunities and challenges for biomaterials science and engineering”, Acta Biomater, 2016, 34, 133-142.
P. Felgueiras, N. S. Murthy, S. D. Sommerfeld, M. M. Bras, V. Migonney and J. Kohn, “Competitive adsorption of plasma proteins using quartz crystal microbalance”, ACS App Mat Interfaces, 2016, 8(21), 13207-13217.
Ezra, J. Bushman, D. Shreiber, M. Schachner and J. Kohn, “Porous and non-porous nerve conduits: The effects of a hydrogel luminal filler with and without a neurite-promoting moeity”, Tissue Eng A, 2016, 22(9-10), 818-826.
Bhatnagar, K. Dube, V. B. Damodaran, G. Subramanian, K. Aston, F. Halperin, M. Mao, K. Pricer, N. S. Murthy and J. Kohn, “Effects of terminal sterilization on PEG-based bioresorbable polymers used in biomedical applications”, Macro Mat Engin, 2016.
Aydin, X. Chu, G. Uppaladadium, D. Devore, R. Goyal, N. S. Murthy, Z. Zhang, J. Kohn and M. Dutt, “Self-Assembly and Critical Aggregation Concentration Measurements of ABA Triblock Copolymers with Varying B Block Types: Model Development, Prediction and Validation”, J. Phys. Chem. B, 2016, 120(15), 3666−3676.
Carlson AL, Bennett NK, Francis NL, Halikere A, Clarke S, Moore JC, Hart RP, Paradiso K, Wernig M, Kohn J, Pang ZP, Moghe PV. Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nature Commuications 2016
Clements BA, Bushman J, Murthy NS, Ezra M, Pastore CM, Kohn J. Design of barrier coatings on kink-resistant peripheral nerve conduits. Journal of Tissue Engineering 2016 (7) 1-14.
2015
Lo MC, Wang S, Singh S, Damodaran VB, Kaplan HM, Kohn J, Shreiber DI, Zahn JD. Coating flexible probes with an ultra fast degrading polymer to aid in tissue insertion. Biomd Microdevices 2015 17:34
Goyal R, Macri L, Kohn J. Formulation Strategy for the Delivery of Cyclosporine A: Comparison of Two Polymeric Nanospheres. Scientific Reports 2015
Vega SL, Dhaliwal A, Arvind V, Patel PJ, Beijer NRM, Boer JD, Murthy NS, Kohn J, Moghe PV. Organizational metrics of interchromatin speckly factor domains: integrative classifier for stem cell adhesion and lineage signaling. 2015 (7) 435-446.
Chen YC, Chen RN, Jhan HJ, Lie DZ, Ho HO, Mao Y, Kohn J, Sheu MT. Development and Characterization of Acellular Extracellular Matrix Scaffolds from Porcine Menisci for Use in Cartilage Tissue Engineering. Tissue Engineering Part C: Methods. 2015 21(9) 971-986.
Kaplan HM, Mishra P, Kohn J. The overwhelming use of rat models in nerve regeneration research may compromise designs of nerve guidance conduits for humans. Journal of Materials Science: Materials in Medicine 2015 26:226
2014
Sommerfeld SD, Zhang Z, Costache MC, Vega SL, Kohn J. Enzymatic Surface Erosion of High Tensile Strength Polycarbonates Based on Natural Phenols. Bimacromolecules 2014 15(3) 830-836
Gajowy J, Bolikal D, Kohn J, El Fray M. Synthesis and Characterixation of Fatty Acid/Amino Acid Self-Assemblies. J. Funct. Biomater. 2014 (4) 211-231.
Lewitus DY, Smith KL, Landers J, Neimark AV, Kohn J. Bioactive agarose carbon-nanotube composites are capable of manipulating brain-implant interface. J. Appl. Polym. Sci. 2014 (131) 40297
Ezra M, Bushman J, Shreiber D, Schachner M, Kohn J. Enhanced Femoral Nerve Regeneration After Tubulization with a Tyrosine-Derived Polycarbonate Terpolymer: Effects of Protein Adsorption and Independence of Conduit Porosity. Tissue Engineering Part A. 2014 20(3-4) 518-528.
Cirillo V, Clements BA, Guarino V, Bushman J, Kohn J, Ambrosio L. A comparison of the performance of mono- and bi-component electrospun conduits in a rat sciatic model. Biomaterials 2014 (32) 8970-8982
2013
Phillip E, Murthy NS, Bolikal D, Narayanan P, Kohn J, Lavelle L, Bodnar S, Pricer K. Ethylene oxide’s role as a reactive agent during sterilization: Effects of polymer composition and device architecture. J. Biomed. Mater. Res. Part B. 2013 (101B) 532-540
Lewitus DY, Rios F, Rojas R, Kohn J. Molecular design and evaluation of biodegradable polymers using a statistical approach. J Mater Sci Mater Med 2013 (24) 2529-2535.
2012
Chatterjee K, Kraigsley AM, Bolikal D, Kohn J, Simon CG. Gas-Foamed Scaffold Gradients for Combinatorial Screening in 3D. J. Functer. Biomat. 2012 3(1) 173-182 .
Carlson AL, Florek CA, Kim JJ, Neubauer T, Moore JC, Cohen RI, Kohn J, Grumet M, Moghe PV. Microfibrous substrate geometry as a critical trigger for organization, self-renewal and differentiation of human embryonic stem cells within synthetic 3-dimensional microenvironments. FASEB 2012 (8) 3240-3251
Shpaisman N, Sheihet L, Bushman J, Winters J, Kohn J. One-Step Synthesis of Biodegradable Curcumin-Derived Hydrogels as Potential Soft Tissue Fillers after Breast Cancer Surgery. Biomacromolecules 2012 13(8) 2279-2286.
Kifyole BE, Sheihet L, Zhang Z, Laohoo M, Kohn J, Michniak-Kohn BB. Development of paclitaxel-TyroSpheres for topical skin treatment. Journal of Controlled Release 2012 (1) 18-24.
Valenzuela LM, Zhang G, Flach CR, Murthy NS, Mendelsohn R, Michniak-Kohn B, Kohn J. Multiscale analysis of water uptake and erosion in biodegradable polyarylates. Polymer Degradation and Stability 2012 (3) 410-420
Khan IJ Murthy NS, Kohn J. Hydration-induced Phase Separation in Amphiphilic Polymer Matrices and its Influence on Voclosporin Release. J. Funct, Biomater. 2012 3(4) 745-759.
Kim, J, Magno MHR, Waters H, Doll BA, McBride S, Alvarez P, Darr A, Vasanji A, Kohn J, Hollinger JO. Tissue Engineering Part A. 2012 18(11-12) 1132-1139.
Tovar N, Murthy NS, Kohn J, Gatt C, Dunn M. ACL reconstruction using a novel hybrid scaffold composed of polyarylate fibers and collagen fibers. Journal of Biomedical Materials Research Part A. 2012 (11) 2913-2920.
Cherry JF, Carlson AL, Benarba FL, Sommerfeld SD, Verma D, Loers G, Kohn J, Schachner M, Moghe PV. Oriented, Multimeric Biointerfaces of the L1 Cell Adhesion Molecule: An Approach to Enhance Neuronal and Neural Stem Cell Functions on 2-D and 3-D Polymer Substrates. Biointerphases 2012 (22)
Luk A, Murthy NS, Wang W, Rojas R, Kohn J. Study of nanoscale structures in hydrated biomaterials using small-angle neutron scattering. Acta Biomaterialia 2012 (4) 1459-1468
Sheihet L, Garbuzenko OB, Bushman J, Gounder MK, Minko T, Kohn J. Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: IN Vivo evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor.European Journal of Pharmaceutical Sciences 2012 (3) 320-329
2011
Lewitus, DY, Landers, J, Branch JR, Smith KL, Callegari G, Kohn J, Neimark AV. Biohybrid carbon nanotube/agarose fibers for neural tissue engineering. Advanced Functional Materials 2011 (21) 2624-2632
Joy A, Cohen DM, Luk A, Anim-Danso E, Chen C, Kohn J. Control over Surface Chemistry, Substrate Stuffness and Cell Function in a Novel Terpolymer Methacrylate Library. Langmuir 2011 (5) 1891-1899.
Valenzuela LM, Michniak B, Kohn J. Variability of water uptake studies of biomedical polymers. Jour. Appl. Poly. Sci. 2011 (121) 1311-1320
Batheja, P. Sheihet L, Kohn J, Singer AJ, Michniak-Kohn B. Topical drug delivery by a polymeric nanosphere gel: Formulation optimization and in vitro and in vivo skin distribution studies. Journal of Controlled Release. 2011 (2) 159-167.
Gubskaya AV, Bonates TO, Kholodovych V, Hammer P, Welsh WJ, Langer R, Kohn J. Logical Analysis of Data in Structure-Activity Investigation of Polymeric Gene Delivery. Macromol. Theory Simul. 2011 (20) 275-285.
Murthy NS, Bedoui F, Kifoyle BE, Iovine C, Michniak-Kohn B, Kohn J. Monitoring the viscoelastic properties of skin in liquid environments using quartz crystal microbalance. Journal of Pharmaceutical Sciences 2011 (2) 530-535
2010
Magno MHR, Kim J, Srinivasan A, McBride S, Bolikal D, Darr A, Hollinger JO, Kohn J. Synthesis, degradation and biocompatibility of tyrosine-derived polycarbonate scaffolds. J. Mater. Chem, 2010 (20) 8885-8893
Sung HJ, Luk A, Murthy NS, Lie E, Jois M, Joy A, Bushman J, Moghe PV, Kohn J. Poly(ethylene glycol) as a sensitive regulator of cell survival fate on polymeric biomaterials: the interplay of cell adhesion and pro-oxidant signaling mechanisms. 2010 (6) 5196-5205
Costache AD, Ghosh J, Knight DD, Kohn J. Computational Methods for the Development of Polymeric Biomaterials. Adv. Eng. Mater. 2010 (12) B3-B17.
Murthy NS, Wang W, Kohn J. Microphase separation in copolymers of hydrophilic PEG blocks and hydrophobic tyrosine-derived segments using simultaneous SAXS/WAXS/DSC. Polymer 51:3978-3988, 2010
Tovar N, Bourke S, Jaffe M, Murthy NS, Kohn J, Gatt C, Dunn M. A comparison of degradable synthetic polymer fibers for anterior cruciate ligament reconstruction. J Biomed Mater Res Part A 2010; 93,738-747.
Chandra P, Lai K, Joon Sung H, Murthy NS, Kohn J. UV laser-ablated surface textures as potential regulator of cellular response. Biointerphases 5:53-59, 2010
Treiser MD, Yang EH, Gordonov S, Cohen DM, Androulakis IP, Kohn J, Chen CS, Moghe PV. Cytoskeleton-based forecasting of stem cell lineage fates. Proc Natl Acad Sci U S A 2010;107(2):610-5.
Johnson PA, Luk A, Demtchouk A, Patel H, Sung HJ, Treiser MD, Gordonov S, Sheihet L, Bolikal D, Kohn J, Moghe PV. Interplay of anionic charge, poly(ethylene glycol), and iodinated tyrosine incorporation within tyrosine-derived polycarbonates: Effects on vascular smooth muscle cell adhesion, proliferation, and motility. J Biomed Mater Res A 2010;93(2):505-14.
2009
Joy A, Anim-Danso E, Kohn J. Simple, rapid, and highly sensitive detection of diphosgene and triphosgene by spectrophotometric methods. Talanta 2009;80(1):231-5.
Costache AD, Sheihet L, Zaveri K, Knight DD, Kohn J. Polymer-drug interactions in tyrosine-derived triblock copolymer nanospheres: a computational modeling approach. Mol Pharm 2009;6(5):1620-7.
Briggs T, Treiser MD, Holmes PF, Kohn J, Moghe PV, Arinzeh TL. Osteogenic differentiation of human mesenchymal stem cells on poly(ethylene glycol)-variant biomaterials. J Biomed Mater Res A, 2009.
Sung HJ, Roskov KE, Kohn J, Becker ML, Moghe PV. High-content profiling of cell responsiveness to graded substrates based on combinatorially variant polymers. Comb Chem High Throughput Screen 2009;12(7):646-55.
Sit PS, Kohn J. Interrelationship of micromechanics and morphology of fibroblasts adhered on different polymeric surfaces. Acta Biomater 2009;5(8):2823-31.
Liu E, Treiser MD, Patel H, Sung HJ, Roskov KE, Kohn J, Becker ML, Moghe PV. High-content profiling of cell responsiveness to graded substrates based on combinyatorially variant polymers. Comb Chem High Throughput Screen 2009;12(7):646-55.
Sung HJ, Chandra P, Treiser MD, Liu E, Iovine CP, Moghe PV, Kohn J. Synthetic polymeric substrates as potent pro-oxidant versus anti-oxidant regulators of cytoskeletal remodeling and cell apoptosis. J Cell Physiol, 2009;218(3):549-57.
2008
2007
Sheihet L, Piotrowska K, Dubin RA, Kohn J, Devore D. Effect of tyrosine-derived triblock copolymer compositions on nanosphere self-assembly and drug delivery. Biomacromolecules 2007;8(3):998-1003.
Kohn J, Welsh WJ, Knight D. A new approach to the rationale discovery of polymeric biomaterials. Biomaterials 2007;28:4171-4177.
Schut J, Bolikal D, Khan IJ, Pesnell A, Rege A, Rojas R, Sheihet L, Murthy NS, Kohn J. Glass transition temperature prediction of polymers through the mass-per-flexible-bond principle. Polymer 2007;48:6115-6124.
Liu E, Treiser MD, Johnson PA, Patel P, Rege A, Kohn J, Moghe PV. Quantitative biorelevant profiling of material microstructure within 3D porous scaffolds via multiphoton fluorescence microscopy. J. Biomed. Mater. Res. Part B: Appl. Biomater. 2007;82B(2):284-297.
Harris NK, Knight D, Kohn J, Welsh WJ. Biomaterials Informatics. In: Narasimham B, Mallpragada SK, editors. Combinatorial Materials Science 2007.
Gubskaya AV, Kholodovych V, Knight D, Kohn J, Welsh WJ. Prediction of fibrinogen adsorption for biodegradable polymers: Integration of molecular dynamics and surrogate modeling. Polymer 2007;48:5788-5801.
Treiser MD, Liu E, Dubin RA, Sung H-J, Kohn J, Moghe PV. Profiling cell-biomaterial interactions via cell-based fluororeporter imaging. BioTechniques 2007;43(3):361-368.
2006
Weber N, Pesnell A, Bolikal D, Zeltinger J, Kohn J. Viscoelastic properties of fibrinogen adsorbed to the surface of biomaterials used in blood-contacting medical devices. Langmuir 2006;23(6):3298-3304.
Sousa A, Sengonul M, Latour R, Kohn J, Libera M. Selective protein adsorption on a phase-separated solvent-cast polymer blend. Langmuir 2006;22(14):6286-6292.
Sousa A, Schut J, Kohn J, Libera M. Nanoscale morphological changes during hydrolytic degradation and erosion of a bioresorbable polymer. Macromolecules 2006;39(21):7306-7312.
Meechaisue C, Dubin R, Supaphol P, Hoven VP, Kohn J. Electrospun mat of tyrosine-derived polycarbonate fibers for potential use as a tissue scaffolding material. J. Biomater. Sci. Polym. Ed. 2006;17(9):1039-1056.
Auguste DT, Armes SP, Brzezinska KR, Deming TJ, Kohn J, Prud’homme RK. pH triggered release of protective poly(ethylene glycol)-b-polycation copolymers from liposomes. Biomaterials 2006;27:2599-2608.
Bailey LO, Becker ML, Stephens JS, Nathan D. Gallant, Mahoney CM, Washburn NR, Rege A, Kohn J, Amis EJ. Cellular response to phase-separated blends of tyrosine-derived polycarbonates. J. Biomed. Mat. Res. 2006;76(3):491-502.
Bae YH, Johnson PA, Florek CA, Kohn J, Moghe PV. Minute changes in composition of polymer substrates produce amplified differences in cell adhesion and motility via optimal ligand conditioning. Acta Biomaterialia 2006;2(5):473-482.
2005
Weber N, Wendel HP, Kohn J. Formation of viscoelastic protein layers on polymeric surfaces relevant to platelet adhesion. J. Biomed. Mater. Res. (Part A) 2005;72A(4):420-427.
Smith JR, Kholodovych V, Knight D, Welsh WJ, Kohn J. QSAR models for the analysis of bioresponse data from combinatorial libraries of polymers. QSAR Comb. Sci. 2005;24:99-113.
Smith JR, Kholodovych V, Knight D, Kohn J, Welsh WJ. Predicting fibrinogen adsorption to polymeric surfaces in silico: a combined method approach. Polymer 2005;46(12):4296-4306.
Sheihet L, Dubin RA, Devore D, Kohn J. Hydrophobic drug delivery by self-assembling triblock copolymer-derived nanospheres. Biomacromolecules 2005;6:2726-2731.
Abramson SD, Alexe G, Hammer PL, Kohn J. A computational approach to predicting cell growth on polymeric biomaterials. J. Biomed. Mat. Res 2005;73A(1):116-124.
Kohn J, Zeltinger J. Degradable, drug-eluting stents: A new frontier for the treatment of coronary artery disease. Future Drugs: Expert Review of Medical Devices 2005;2(6):667-671.
2004
Smith JR, Seyda A, Weber N, Knight D, Abramson S, Kohn J. Integration of combinatorial synthesis, rapid screening, and computational modeling in biomaterials development. Macromol. Rapid Commun. 2004;25:127–140.
Nardin C, Bolikal D, Kohn J. Nontoxic block copolymer nanospheres: Design and characterization. Langmuir 2004;20((26)):11721-5.
Kohn J. New approaches to biomaterials design. Nature Materials 2004;3:745-747.
Fang JB, Sanghi R, Kohn J, Goldman AS. Tantalum pentachloride as a coupling agent for stereohindered amide bond formation. Inorg. Chim. Acta 2004;357:2415-2426.
Weber N, Bolikal D, Bourke SL, Kohn J. Small changes in the polymer structure influence the adsorption behavior of fibrinogen on polymer surfaces: Validation of a new rapid screening technique. J. Biomed. Mater. Res. 2004;68(A):496-503.
Sousa A, Aitouchen A, Kohn J, Libera M. Quantitative EELS imaging of phase-separated morphology in poly(DTE carbonate)-poly(caprolactone) thin-film blends. Microsc. Microanal. 2004;10(Supplement S02):1426-1427.
Smith JR, Knight D, Kohn J, Rasheed K, Weber N, Kholodovych V, Welsh WJ. Using surrogate modeling in the prediction of fibrinogen adsorption onto polymer surfaces. J. Chem. Inf. Comput. Sci. 2004;44:1088-1097.
Kholodovych V, Smith JR, Knight D, Abramson S, Kohn J, Welsh WJ. Accurate Predictions of Cellular Response using QSPR: A Feasibility Test of Rational Design of Polymeric Biomaterials. Polymer 2004;45:7367-7379.
Hoven VP, Poopattanapong A, Kohn J. Acid-containing tyrosine-derived polycarbonates: Wettability and surface reactivity. Macromol. Symp. 2004;216(1):87-97.
Bourke SL, Kohn J, Dunn MG. Preliminary development of a novel resorbable synthetic polymer fiber scaffold for anterior cruciate ligament reconstruction. Tissue Engineering 2004;10(1):43-52.
Zeltinger J, Schmid E, Brandom D, Bolikal D, Pesnell A, Kohn J. Advances in the development of coronary stents. Biomaterials Forum (Official Newsletter of the Society for Biomaterials) 2004;26(1):8-24.
Bourke SL, Kohn J, Dunn MG. Preliminary development of a novel resorbable synthetic polymer fiber scaffold for anterior cruciate ligament reconstruction. Tissue Engineering 2004;10(1):43-52.
Sharma RI, Kohn J, Moghe PV. Poly(ethylene glycol) enhances cell motility on protein-based poly(ethylene glycol)-polycarbonate substrates: A mechanism for cell-guided ligand remodeling. J. Biomed. Mater. Res., Part A 2004;69A(1):114-123.
2003
Bourke SL, Kohn J. Polymers derived from the amino acid L-tyrosine: Polycarbonates, polyarylates and copolymers with poly(ethylene glycol). Adv. Drug Del. Rev. 2003;55(4):447-466.
Bourke SL, Al-Khalili M, Briggs T, Michniak BB, Kohn J, Poole-Warren LA. A photo-crosslinked poly(vinyl alcohol) hydrogel growth factor release vehicle for wound healing applications. AAPS PharmSci. 2003;5 article 33(4):article 33.
Auguste DT, Prud’homme RK, Ahl PL, Meers P, Kohn J. Association of hydrophobically modified poly(ethylene glycol) with fusogenic liposomes. Biochim. Biophys. Acta 2003;1616:184-195.
2002
Yang B-S, Lal J, Mihailescu M, Monkenbusch M, Richter D, Huang JS, Kohn J, Russel WB, Prud’homme RK. Neutron spin-echo study of dynamics of hydrophobically modified polymer-doped surfactant bilayers. Langmuir 2002;18:6-13.
Schachter DM, Kohn J. A synthetic polymer matrix for the delayed or pulsatile release of water-soluble peptides. J. Control. Rel. 2002;78:143-153.
Perez-Luna VH, Kohn J, Graham DJ, Ratner BD. Poly(desaminotyrosyl-tyrosine carbonate ethyl ester) studied by XPS.Surf. Sci. Spectra 2002;9:6-11.
d’Acunzo F, Kohn J. Alternating multiblock amphiphilic copolymers of PEG and tyrosine-derived diphenols. I. Synthesis and characterization. Macromolecules 2002;35:9360-9365.
d’Acunzo F, Le TQ, Kohn J. Alternating multiblock amphiphilic copolymers of PEG and tyrosine-derived diphenols. II. Self-assembly in aqueous solution and at hydrophobic surfaces. Macromolecules 2002;35:9366-9371.
Jaffe M, Pai V, Ophir Z, Wu J, Kohn J. Process-structure-property relationships of erodable polymeric biomaterials, I: Poly(desaminotyrosyl arylates). Pol. Adv. Tech. 2002;13:926-937.
2001
Yang B-S, Lal J, Kohn J, Huang JS, Russel WB, Prud’homme RK. Interaction of surfactant lamellar phase and a strictly alternating comb-graft amphiphilic polymer based on PEG. Langmuir 2001;17(21):6692-6698.
Hwang ML, Prud’homme RK, Kohn J, Thomas JL. Stabilization of phosphatidylserine/phosphatidylethanolamine liposomes with hydrophilic polymers having multiple “Sticky Feet”. Langmuir 2001;17(25):7713-7716.
Suarez N, Brocchini S, Kohn J. Study of relaxation mechanisms in structurally related biomaterials by thermally stimulated depolarization currents. Polymer 2001;42(21):8671-8680.
Ryan PL, Foty RA, Kohn J, Steinberg M. Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity. Proc. Natl. Acad. Sci. 2001;98(8):4323-4327.
2000
Tangpasuthadol V, Pendharkar SM, Kohn J. Hydrolytic degradation of tyrosine-derived polycarbonates, a class of new biomaterials. Part I: Study of model compounds. Biomaterials 2000;21:2371-2378.
Tangpasuthadol V, Pendharkar SM, Peterson RC, Kohn J. Hydrolytic degradation of tyrosine-derived polycarbonates, a class of new biomaterials. Part II: 3-yr study of polymeric devices. Biomaterials 2000;21:2379-2387.
Belu AM, Brocchini S, Kohn J, Ratner BD. Characterization of combinatorially designed polyarylates by time-of-flight secondary ion mass spectrometry. Rapid Commun. Mass Spectrom. 2000;14:564-571.
Tziampazis E, Kohn J, Moghe PV. PEG-variant biomaterials as selectively adhesive protein templates: Model surfaces for controlled cell adhesion and migration. Biomaterials 2000;21:511-520.
Hooper KA, Nickolas TL, Yurkow EJ, Kohn J, Laskin DL. Characterization of the inflammatory response to biomaterials using a rodent air pouch. J. Biomed. Mater. Res. 2000;50:365-374.
1999
Yu C, Mielewczyk SS, Breslauer KJ, Kohn J. Tyrosine-PEG-derived poly(ether carbonate)s as new biomaterials. Part II: Study of inverse temperature transitions. Biomaterials 1999;20(3):265-272.
Yu C, Kohn J. Tyrosine-PEG-derived poly(ether carbonate)s as new biomaterials. Part I: Synthesis and Evaluation. Biomaterials 1999;20(3):253-264.
Heitz C, Prud’homme RK, Kohn J. A new, strictly alternating, comb-like amphiphilic polymer based on PEG: Part 2: Associative behavior of a high molecular weight sample and interaction with SDS. Macromolecules 1999;32(20):6658 – 6667.
Heitz C, Pendharkar S, Prud’homme RK, Kohn J. A new, strictly alternating, comb-like amphiphilic polymer based on PEG: Part 1: Synthesis and associative behavior of a low molecular weight sample. Macromolecules 1999;32(20):6652 – 6657.
Puma M, Suarez N, Kohn J. Conductivity and high-temperature relaxation of tyrosine-derived polyarylates measured with thermal stimulated currents. J. Polym. Sci. Part B: Polym. Phys. 1999;37:3504-3511.
James K, Levene H, Parsons JR, Kohn J. Small changes in polymer chemistry have a large effect on the bone-implant interface: Evaluation of a series of degradable tyrosine-derived polycarbonates in bone defects. Biomaterials 1999;20(23/24):2203-2212.
1998
Brocchini S, James K, Tangpasuthadol V, Kohn J. Structure-property correlations in a combinatorial library of degradable biomaterials. J. Biomed. Mater. Res. 1998;42:66-75.
Suarez N, Brocchini S, Kohn J. The study of water uptake in degradable polymers by thermally stimulated depolarization currents. Biomaterials 1998;19:2347-2356.
Lhommeau C, Levene H, Abramson S, Kohn J. Preparation of highly interconnected porous, tyrosine-derived polycarbonate scaffolds. Tissue Engineering 1998;4(4):468.
Hooper KA, Macon ND, Kohn J. Comparative histological evaluation of new tyrosine-derived polymers and poly(L-lactic acid) as a function of polymer degradation. J. Biomed. Mater. Res. 1998;41(3):443-454.
1997
Poiani GJ, Kemnitzer JE, Fox JD, Tozzi CA, Kohn J, Riley DJ. Polymeric carrier of proline analogue with antifibrotic effect in pulmonary vascular remodeling. Amer. J. Respir. Crit. Care Med. 1997;155(4):1384-1390.
Hooper KA, Cox JD, Kohn J. Comparison of the effect of ethylene oxide and γ-irradiation on selected tyrosine-derived polycarbonates and poly(L-lactic acid). J. Appl. Polym. Sci. 1997;63(11):1499-1510.
Greco MJ, Kemnitzer JE, Fox JD, Jin K. Choe, Kohn J, Riley DJ, Poiani GJ. Polymer of proline analogue with sustained antifibrotic activity in lung fibrosis. Amer. J. Respir. Crit. Care Med. 1997;155(4):1391-1397. –
Brocchini S, James K, Tangpasuthadol V, Kohn J. A combinatorial approach for polymer design. J. Amer. Chem. Soc. 1997;119(19):4553-4554.
Tangpasuthadol V, Shefer A, Yu C, Zhou J, Kohn J. Thermal properties and enthalpy relaxations of tyrosine-derived polyarylates. J. Appl. Polym. Sci. 1997;63(11):1441-1448.
Suarez N, Laredo E, Bello A, Kohn J. Molecular relaxation mechanisms of tyrosine-derived polycarbonates by thermally stimulated depolarization currents. J. Appl. Polym. Sci. 1997;63(11):1457-1466.
Ramanujachary KV, Tong X, Lu Y, Kohn J, Greenblatt M. Lithium ionic conductivity in poly(ether urethanes) derived from poly(ethylene glycol) and lysine ethyl ester. J. Appl. Polym. Sci. 1997;63(11):1449-1456.
Perez-Luna VH, Hooper KA, Kohn J, Ratner BD. Surface characterization of tyrosine-derived polycarbonates. J. Appl. Polym. Sci. 1997;63(11):1467-1479.
Hooper KA, Cox JD, Kohn J. Comparison of the effect of ethylene oxide and γ-irradiation on selected tyrosine-derived polycarbonates and poly(L-lactic acid). J. Appl. Polym. Sci. 1997;63(11):1499-1510.
1996
James K, Kohn J. New biomaterials for tissue engineering. MRS Bulletin 1996;21(11):22-26.
Tangpasuthadol V, Shefer A, Hooper KA, Kohn J. Thermal properties and physical aging behavior of tyrosine-derived polycarbonates. Biomaterials 1996;17(4):463-468.
Kohn J. Tissue engineering: An overview. MRS Bulletin 1996;21(11):18-19.
James K, Kohn J. Applications of pseudo-poly(amino acid) biomaterials. Trends Polym. Sci. 1996;4(12):394-397.
Choueka J, Charvet JL, Koval KJ, Alexander H, James KS, Hooper KA, Kohn J. Canine bone response to tyrosine-derived polycarbonates and poly(L-lactic acid). J. Biomed. Mater. Res. 1996;31:35-41.
1995
Hooper KA, Kohn J. Diphenolic monomers derived from the natural amino acid α-L-tyrosine: An evaluation of peptide coupling techniques. J. Bioact. Compat. Polym. 1995;10(4):327-340.
Gomez MA, Marco C, Fatou JMG, Suarez N, Laredo E, Bello A. Relaxations in liquid crystalline poly(tetraethylene oxide terephthaloyl-bis-4-oxybenzoate). J. Polym. Sci., Part B: Polym. Phys. 1995;33(8):1259-1267.
Ertel SI, Kohn J, Zimmerman MC, Parsons JR. Evaluation of poly(DTH carbonate), a tyrosine-derived degradable polymer, for orthopaedic applications. J. Biomed. Mater. Res. 1995;29(11):1337-1348.
1994
Vyavahare N, Kohn J. Photocrosslinked hydrogels based on copolymers of poly(ethylene glycol) and lysine. J. Polym. Sci. Part A: Polym. Chem. 1994;32(7):1271-1281.
Poiani GJ, Riley DJ, Fox JD, Kemnitzer JE, Gean KF, Kohn J. Conjugates of cis-4-hydroxy-L-proline and poly(PEG-Lys), a water-soluble poly(ether urethane): Synthesis and evaluation of antifibrotic effects in vitro and in vivo. Bioconj. Chem. 1994;5:621-630.
Parkinson GN, Fan P, Wu Y, Kohn J, Baum J, Berman HM. Crystal structure and NMR conformation of a cyclic pseudotetrapeptide containing urethane backbone linkages. Biopolymers 1994;34:403-414.
Nathan A, Zalipsky S, Kohn J. Strategies for covalent attachment of doxorubicin to poly(PEG-Lys), a new water-soluble poly(ether urethane). J. Bioact. Compat. Polym. 1994;9:239-251. Strategies for covalent attachment of doxorubicin to poly(PEG-Lys), a new water-soluble poly(ether urethane).
Nathan A, Kohn J. Amino acid derived polymers. In: Shalaby SW, editor. Designed to Degrade Biomedical Polymers. New York, NY: Hanser Publishers; 1994. p 117-151.
Fiordeliso J, Bron S, Kohn J. Design, synthesis, and preliminary characterization of tyrosine-containing polyarylates: New biomaterials for medical applications. J. Biomater. Sci. (Polym. Ed.) 1994;5(6):497-510.
Ertel SI, Kohn J. Evaluation of a series of tyrosine-derived polycarbonates for biomaterial applications. J. Biomed. Mater. Res. 1994;28:919-930.
Stemberger A, Alt E, Schmidmaier G, Kohn J, Blümel G. Blood compatible biomaterials through resorbable anticoagulant drugs with coatings. Ann. Hematol. 1994;68(supplement II):A48.
1993
Vyavahare N, Scott NA, Hanson SR, Kohn J. In vitro and in vivo evaluation of the site-specific administration of D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone (PPACK): A powerful thrombin inhibitor. J. Control. Rel. 1993;27:165-173.
Poiani GJ, Gean KF, Fox JD, Kohn J, Riley DJ. Antifibrotic effect of a proline analogue delivered in liposomes to cells in culture. Amino Acids 1993;4:237-248.
Nathan A, Zalipsky S, Ertel SI, Agathos SN, Yarmush ML, Kohn J. Copolymers of lysine and polyethylene glycol: A new family of functionalized drug-carriers. Bioconj. Chem. 1993;4:54-62.
Kohn J. Design, synthesis, and possible applications of pseudo-poly(amino acids). Trends Polym. Sci. 1993;1(7):206-212.
1992
Silver FH, Marks M, Kato YP, Li C, Pulapura S, Kohn J. Tissue compatibility of tyrosine derived polycarbonates and polyiminocarbonates: An initial evaluation. J. Long-Term Effects Med. Implants 1992;1(4):329-346.
Nathan A, Bolikal D, Vyavahare N, Zalipsky S, Kohn J. Hydrogels based on water-soluble poly(ether urethanes) derived from L-lysine and poly(ethylene glycol). Macromolecules 1992;25:4476-4484.
Pulapura S, Kohn J. Trends in the development of bioresorbable polymers for medical applications. J. Biomater. Appl. 1992;6:216-250.
Pulapura S, Kohn J. Tyrosine derived polycarbonates: Backbone modified, “pseudo”-poly(amino acids) designed for biomedical applications. Biopolymers 1992;32:411-417.
Joshi K, Bao J, Goldman AS, Kohn J. Acylation reactions mediated by tantalum carboxylates. J. Am. Chem. Soc. 1992;114:6649-6652.
Gelbin ME, Kohn J. Synthesis and polymerization of N-Z-L-serine-β-lactone and N-protected serine hydroxybenzotriazole active esters. J. Am. Chem. Soc. 1992;114:3962-3965.
1991
Kohn J. The use of natural metabolites in the design of non-toxic polymers for medical applications. Polymer News 1991;16(11):325-332.
Wu Y, Kohn J. New macrocyclic pseudopeptides containing urethane backbone linkages. J. Am. Chem. Soc. 1991;113:687-688.
Li C, Kohn J. Macromolecular backbone rearrangements: A new approach to the synthesis of N-phenyl-substituted polyurethanes. Macromolecules 1991;24:2302-2308.
Kohn J. Pseudo-poly(amino acids). Drug News and Perspectives 1991;4(5):289-294.
1990
Pulapura S, Li C, Kohn J. Structure-property relationships for the design of polyiminocarbonates. Biomaterials 1990;11:666-678.
Zhou QX, Kohn J. Preparation of poly(L-serine ester): A structural analogue of conventional poly(L-serine). Macromolecules 1990;23:3399-3406.
Recht J, Cohen BI, Goldman AS, Kohn J. High oxidation state transition metal carboxylates as acylating agents. Tetrahed. Lett. 1990;31(50):7281-7284.
Kohn J. Current trends in the development of synthetic materials for medical applications. Pharm. Technol. 1990;14(10):32-41.
1989
Li C, Kohn J. Synthesis of poly(iminocarbonates): Degradable polymers with potential applications as disposable plastics and as biomaterials. Macromolecules 1989;22(5):2029-2036.
1987
Kohn J, Langer R. Polymerization reactions involving the side chains of α-L-amino acids. J. Am. Chem. Soc. 1987;109:817-820.
1986
Kohn J, Langer R. Poly(iminocarbonates) as potential biomaterials. Biomaterials 1986;7:176-181.
Kohn J, Albert EC, Wilchek M, Langer R. Identification and colorimetric determination of organic cyanates in nanomolar quantities. Anal. Chem. 1986;58:3184-3188.